› Forums › General Melanoma Community › Help with pathology report
- This topic has 18 replies, 4 voices, and was last updated 9 years, 6 months ago by
Janner.
- Post
- Replies
-
-
- September 23, 2016 at 11:01 pm
Yes if you post it here there might be people who can help.
Julie
-
- September 24, 2016 at 12:01 am
Here is what came back from my biopsy on the pathology report. Any that can give me some information from it I would greatly appreciate it.
– Diagnosis:
-A. Skin, left upper arm, shave biopsy:
– Malignant melanoma, superficial spreading type, with the following features:
– Approximate Breslow thickness: At least 0.50cm
– Clark's level: At least IV
– Ulceration: Not identified
– Mitoses: None identified
– Lymphocytic infiltrate: Non-brisk
– Rregression: Patchy dermal fibrosis and mild chronic inflammation compatible with partial regression
– Lymphovascular invasion: Not identified
– Perineural invasion: Not identified
– Satellitosis: Not Identified
– Melanoma in siut: Present
– Margins: Involved
Sections show skin with an atypical melanocytic proliferation located both at the dermoepidermal junction and within the dermis. Junctional melanocytes are arranged in variably sized nests as well as a prominent single cell growth pattern. MART-1/tyrosinase immunostain is performed and there are areas of confluent growth as well as pagetoid spread. Similarly atypical melanocytes are present within the dermis and are associated with patchy fibrosis and chronic inflammation. There is also a separate population of melanocytes within the dermis that appears fairly bland which is consistant with antecedent nevus. The invasive component is present at the deep inked margin. Therefore, the above Breslow thickness and Clark's level are estimations. Appropriate re-excision and clinical follow-up are recommended.
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 4:31 pm
I would ask about a sentinel node biopsy BEFORE your wide excision appointment. This procedure can only be done prior to the wide excision. The test may not be accurate when done after the excision. Lymph nodes are usually tested when the melanoma is over 1mm but since you do not know your full depth, it makes sense to ask the question now and not wish you had done that procedure later.
-
- September 24, 2016 at 4:31 pm
I would ask about a sentinel node biopsy BEFORE your wide excision appointment. This procedure can only be done prior to the wide excision. The test may not be accurate when done after the excision. Lymph nodes are usually tested when the melanoma is over 1mm but since you do not know your full depth, it makes sense to ask the question now and not wish you had done that procedure later.
-
- September 24, 2016 at 4:31 pm
I would ask about a sentinel node biopsy BEFORE your wide excision appointment. This procedure can only be done prior to the wide excision. The test may not be accurate when done after the excision. Lymph nodes are usually tested when the melanoma is over 1mm but since you do not know your full depth, it makes sense to ask the question now and not wish you had done that procedure later.
-
- September 24, 2016 at 5:45 am
Hi,
From my understanding..
They have identified a superficial spreading melanoma.
It was a shave biopsy and the whole of it has not been removed so from the bit sent to the lab they can only estimate the clarks level and breslow thickness.
No ulceration that is good
It has features that indicate it may have regressed. is your immune system has attacked it and made some of the melanoma e!ement go away.
No satellites ie smaller in transit lesions around the main.. But given not the whole removed . this is to be expected.
The melanoma needs to be fully surgically removed from your arm with clear margins .
If you go to cancer research UK type in melanoma and breslow and Clark's level there is more detail to get your head around.
The big messages are. There is still some melanoma that needs removing surgically in order to leave a clear margin.
Some of the form refers to features you might see in a larger tissue sample and because this is small and needs complete excision it does not tell you a lot.
So you need to get it removed and you may be advised to have a sentinel lymph node biopsy done at the same time to check for spreadvia the lymphatics. Because it was a shave biopsy it will be difficult to add the two bits of depth together to get an accurate measure of the maximum thickness.
Good luck..posting now before out of charge
-
- September 24, 2016 at 12:01 am
Here is what came back from my biopsy on the pathology report. Any that can give me some information from it I would greatly appreciate it.
– Diagnosis:
-A. Skin, left upper arm, shave biopsy:
– Malignant melanoma, superficial spreading type, with the following features:
– Approximate Breslow thickness: At least 0.50cm
– Clark's level: At least IV
– Ulceration: Not identified
– Mitoses: None identified
– Lymphocytic infiltrate: Non-brisk
– Rregression: Patchy dermal fibrosis and mild chronic inflammation compatible with partial regression
– Lymphovascular invasion: Not identified
– Perineural invasion: Not identified
– Satellitosis: Not Identified
– Melanoma in siut: Present
– Margins: Involved
Sections show skin with an atypical melanocytic proliferation located both at the dermoepidermal junction and within the dermis. Junctional melanocytes are arranged in variably sized nests as well as a prominent single cell growth pattern. MART-1/tyrosinase immunostain is performed and there are areas of confluent growth as well as pagetoid spread. Similarly atypical melanocytes are present within the dermis and are associated with patchy fibrosis and chronic inflammation. There is also a separate population of melanocytes within the dermis that appears fairly bland which is consistant with antecedent nevus. The invasive component is present at the deep inked margin. Therefore, the above Breslow thickness and Clark's level are estimations. Appropriate re-excision and clinical follow-up are recommended.
-
- September 24, 2016 at 12:01 am
Here is what came back from my biopsy on the pathology report. Any that can give me some information from it I would greatly appreciate it.
– Diagnosis:
-A. Skin, left upper arm, shave biopsy:
– Malignant melanoma, superficial spreading type, with the following features:
– Approximate Breslow thickness: At least 0.50cm
– Clark's level: At least IV
– Ulceration: Not identified
– Mitoses: None identified
– Lymphocytic infiltrate: Non-brisk
– Rregression: Patchy dermal fibrosis and mild chronic inflammation compatible with partial regression
– Lymphovascular invasion: Not identified
– Perineural invasion: Not identified
– Satellitosis: Not Identified
– Melanoma in siut: Present
– Margins: Involved
Sections show skin with an atypical melanocytic proliferation located both at the dermoepidermal junction and within the dermis. Junctional melanocytes are arranged in variably sized nests as well as a prominent single cell growth pattern. MART-1/tyrosinase immunostain is performed and there are areas of confluent growth as well as pagetoid spread. Similarly atypical melanocytes are present within the dermis and are associated with patchy fibrosis and chronic inflammation. There is also a separate population of melanocytes within the dermis that appears fairly bland which is consistant with antecedent nevus. The invasive component is present at the deep inked margin. Therefore, the above Breslow thickness and Clark's level are estimations. Appropriate re-excision and clinical follow-up are recommended.
-
- September 23, 2016 at 11:01 pm
Yes if you post it here there might be people who can help.
Julie
-
- September 23, 2016 at 11:01 pm
Yes if you post it here there might be people who can help.
Julie
-
- You must be logged in to reply to this topic.