Help With Path Report/Prognosis
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Help With Path Report/Prognosis

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  • Post
    • April 30, 2013 at 10:14 am
    JC
    Participant

    "Severely atypical compound melanocytic proliferation consistent with at least melanoma in-situ arising in association with a compound dysplastic nevus with features suggestive of partial regression and with foci suspicious for early invasive melanoma extending to a depth of approximately 0.30 mm.  The differential diagnosis would include melanoma in-situ arising within a compound dysplastic nevus that either has been irritated or undergone partial regression or a early superficially invasive melanoma arising within a compound dysplastic nevus with regression.  I favor early

    "Severely atypical compound melanocytic proliferation consistent with at least melanoma in-situ arising in association with a compound dysplastic nevus with features suggestive of partial regression and with foci suspicious for early invasive melanoma extending to a depth of approximately 0.30 mm.  The differential diagnosis would include melanoma in-situ arising within a compound dysplastic nevus that either has been irritated or undergone partial regression or a early superficially invasive melanoma arising within a compound dysplastic nevus with regression.  I favor early invasive melanoma because some of the melanocytes within the papillary dermis demonstrate similar cytologic atypia to the ones seen in the epidermis.  The atypical melanocytes extend to a depth of approximately 0.30 mm.  The stage would be pT1a.  The melanocytic proliferation appears narrowly excised in planes of section.  A re-excision as clinically indicated is recommended."  Also goes on to say, "Dermal mitoses are not identified."  There is a lot of vocabulary here I don't understand what it all means, but I know melanoma is serious.

Viewing 8 reply threads
  • Replies
      • April 30, 2013 at 1:18 pm
      MichaelFL
      Participant

      My pathology was similar to yours except I had a 1 mitosis. My depth was also .30 mm.

      You are classified as stage 1a. Your melanoma depth (called Breslow depth) is .30 mm.

      Dermal mitosis is merely the rate of cell division. Not identified is a good thing as it means no cells were dividing in the area viewed under the microscope. Some would call that 0 mitosis.

       "A re-excision as clinically indicated" is standard protocol to verify clear margins.

      Your prognosis is excellent!

       

      • April 30, 2013 at 1:18 pm
      MichaelFL
      Participant

      My pathology was similar to yours except I had a 1 mitosis. My depth was also .30 mm.

      You are classified as stage 1a. Your melanoma depth (called Breslow depth) is .30 mm.

      Dermal mitosis is merely the rate of cell division. Not identified is a good thing as it means no cells were dividing in the area viewed under the microscope. Some would call that 0 mitosis.

       "A re-excision as clinically indicated" is standard protocol to verify clear margins.

      Your prognosis is excellent!

       

      • April 30, 2013 at 1:18 pm
      MichaelFL
      Participant

      My pathology was similar to yours except I had a 1 mitosis. My depth was also .30 mm.

      You are classified as stage 1a. Your melanoma depth (called Breslow depth) is .30 mm.

      Dermal mitosis is merely the rate of cell division. Not identified is a good thing as it means no cells were dividing in the area viewed under the microscope. Some would call that 0 mitosis.

       "A re-excision as clinically indicated" is standard protocol to verify clear margins.

      Your prognosis is excellent!

       

      • April 30, 2013 at 1:31 pm
      JC
      Participant

      So, after the re-excision, I just go about business as usual, no further medical stuff with this?

      • April 30, 2013 at 1:31 pm
      JC
      Participant

      So, after the re-excision, I just go about business as usual, no further medical stuff with this?

      • April 30, 2013 at 1:31 pm
      JC
      Participant

      So, after the re-excision, I just go about business as usual, no further medical stuff with this?

        • April 30, 2013 at 1:42 pm
        Janner
        Participant

        Surgery to get the margins is the next step.  After that, you continue to watch for any moles that change, watch this scar area for any pigment regrowth, see your derm periodically and practice sun safety.  This is a very low risk lesion, but it isn't a no risk lesion.  But in general, the surgery takes care of these very early lesions and there is no treatment or "further medical stuff" once you have the WLE (wide local excision).

        Best wishes,

        Janner

        • April 30, 2013 at 1:42 pm
        Janner
        Participant

        Surgery to get the margins is the next step.  After that, you continue to watch for any moles that change, watch this scar area for any pigment regrowth, see your derm periodically and practice sun safety.  This is a very low risk lesion, but it isn't a no risk lesion.  But in general, the surgery takes care of these very early lesions and there is no treatment or "further medical stuff" once you have the WLE (wide local excision).

        Best wishes,

        Janner

        • April 30, 2013 at 1:42 pm
        Janner
        Participant

        Surgery to get the margins is the next step.  After that, you continue to watch for any moles that change, watch this scar area for any pigment regrowth, see your derm periodically and practice sun safety.  This is a very low risk lesion, but it isn't a no risk lesion.  But in general, the surgery takes care of these very early lesions and there is no treatment or "further medical stuff" once you have the WLE (wide local excision).

        Best wishes,

        Janner

        • April 30, 2013 at 7:11 pm
        MichaelFL
        Participant

        Not quite, after what is called the WLE is performed (wide local excision) they will verify clear margins. Then you will most likely have a discussion with your derm and continue to see them on a 6 month interval.

        You should always check your moles yourself monthly for change too.

        As I said, your prognosis is excellent! Pat yourself on the back for catching this as early as you did. Early detection is the key!

         

         

        • April 30, 2013 at 7:11 pm
        MichaelFL
        Participant

        Not quite, after what is called the WLE is performed (wide local excision) they will verify clear margins. Then you will most likely have a discussion with your derm and continue to see them on a 6 month interval.

        You should always check your moles yourself monthly for change too.

        As I said, your prognosis is excellent! Pat yourself on the back for catching this as early as you did. Early detection is the key!

         

         

        • April 30, 2013 at 7:11 pm
        MichaelFL
        Participant

        Not quite, after what is called the WLE is performed (wide local excision) they will verify clear margins. Then you will most likely have a discussion with your derm and continue to see them on a 6 month interval.

        You should always check your moles yourself monthly for change too.

        As I said, your prognosis is excellent! Pat yourself on the back for catching this as early as you did. Early detection is the key!

         

         

      • April 30, 2013 at 1:52 pm
      JC
      Participant

      Thank you.  What kind of risk are we talking about here?

      • April 30, 2013 at 1:52 pm
      JC
      Participant

      Thank you.  What kind of risk are we talking about here?

      • April 30, 2013 at 1:52 pm
      JC
      Participant

      Thank you.  What kind of risk are we talking about here?

        • April 30, 2013 at 2:20 pm
        Janner
        Participant

        Melanoma has the ability to metastasize.  The survival rate for a stage IA lesion is not 100% although it is in the very high 90's.  There are no treatments for early stage melanoma beyond surgery.  So go about and live life as normal, but pay attention to your body and what is normal for you, then if anything unusual shows up, get it checked out. 

        Best wishes,

        Janner

        Stage 1B since 1992

        • April 30, 2013 at 2:20 pm
        Janner
        Participant

        Melanoma has the ability to metastasize.  The survival rate for a stage IA lesion is not 100% although it is in the very high 90's.  There are no treatments for early stage melanoma beyond surgery.  So go about and live life as normal, but pay attention to your body and what is normal for you, then if anything unusual shows up, get it checked out. 

        Best wishes,

        Janner

        Stage 1B since 1992

        • April 30, 2013 at 2:20 pm
        Janner
        Participant

        Melanoma has the ability to metastasize.  The survival rate for a stage IA lesion is not 100% although it is in the very high 90's.  There are no treatments for early stage melanoma beyond surgery.  So go about and live life as normal, but pay attention to your body and what is normal for you, then if anything unusual shows up, get it checked out. 

        Best wishes,

        Janner

        Stage 1B since 1992

        • May 29, 2013 at 11:45 am
        JC
        Participant

        I feel like not doing anything except the wide excision is just like rolling the dice and hoping it doesn't come up metastatic.  There's nothing more that can be done except just hoping you get lucky?

        • May 29, 2013 at 11:45 am
        JC
        Participant

        I feel like not doing anything except the wide excision is just like rolling the dice and hoping it doesn't come up metastatic.  There's nothing more that can be done except just hoping you get lucky?

        • May 29, 2013 at 11:45 am
        JC
        Participant

        I feel like not doing anything except the wide excision is just like rolling the dice and hoping it doesn't come up metastatic.  There's nothing more that can be done except just hoping you get lucky?

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