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GSK Mek Great Scans!

Forums General Melanoma Community GSK Mek Great Scans!

  • Post
    sharmon
    Participant

      Hi  An update on Brent,  He has been on the trial since Feb.  He is feeling good and is still working with a Local derm on antibiotics and creams to help with the really really bad rash.  The derm here in Bradenton Fl  was instrumental in producing a cream that is being tested in a trial in CA for inhibitors induced rash.  He is really looking better each day. 

      Anyway overall 30 percent reduction and no new mets.  

      Hi  An update on Brent,  He has been on the trial since Feb.  He is feeling good and is still working with a Local derm on antibiotics and creams to help with the really really bad rash.  The derm here in Bradenton Fl  was instrumental in producing a cream that is being tested in a trial in CA for inhibitors induced rash.  He is really looking better each day. 

      Anyway overall 30 percent reduction and no new mets.  

      The week before his scans and the week after the scans  we moved out of our house and into a motorhome.  We are going to travel for 2 months.  He was tired but it was doable for him.

      We are Blessed.

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    • Replies
        emilypen
        Participant

          Awesome, such good news. My  hubby starts the GSK Mek inhibitor in 2 weeks and it's good to hear that its working out there.

          Have a great trip.

           

          Emily

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          killmel
          Participant

            Hi Sharmon,

             

            Great news….hope he continues to do well.

            Can you tell us more about the cream. I live in CA with my sister & she also has a terrible rash from inhibitors.

            Where can she get the cream. Where/who has the trial on the cream? Any info would be sincerely appreciated.

             

            Wish continue success with treatment.

             

             

             

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              sharmon
              Participant

                Hi, 

                The cream that is working for him is mupirocin and the antibiotic is dicoxacillin 250 mg  It is one Capsule 2 times a day.

                I will more time to locate the trial information.  I found it looking up dicoxacillin clinical trials for mek inhibitors.

                 

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                sharmon
                Participant

                  Hi ,  Brent also soaks his face and scalp by submerging in warm salt water.  Derm recommended.

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                  sharmon
                  Participant

                    Hi ,  Brent also soaks his face and scalp by submerging in warm salt water.  Derm recommended.

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                  Lori CO
                  Participant

                    Love to see this!! Thanks for posting. Have a great trip.

                    Lori

                    Stage IV

                    Grand Junction, CO

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                    Lori CO
                    Participant

                      Love to see this!! Thanks for posting. Have a great trip.

                      Lori

                      Stage IV

                      Grand Junction, CO

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                      King
                      Participant

                        This is wonderful news, Sharon!!!!  Reduction…yeah!  I'm so happy that the travel will be happening.

                        Stay Strong
                        Kathie

                        Stage IV 7/05 Liver mets

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                        King
                        Participant

                          This is wonderful news, Sharon!!!!  Reduction…yeah!  I'm so happy that the travel will be happening.

                          Stay Strong
                          Kathie

                          Stage IV 7/05 Liver mets

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                          Rocklove
                          Participant

                            It's so good to hear good news Sharon. I hope You and Brent have a wonderful time together the next few months traveling. Please keep us updated as so many of us are praying for You two.

                            Rocky

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                            Rocklove
                            Participant

                              It's so good to hear good news Sharon. I hope You and Brent have a wonderful time together the next few months traveling. Please keep us updated as so many of us are praying for You two.

                              Rocky

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                              triciad
                              Participant

                                Congratulations!  Here's to continued success!  Enjoy your travels.

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                                triciad
                                Participant

                                  Congratulations!  Here's to continued success!  Enjoy your travels.

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                                  Nurse Pat
                                  Participant

                                    What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

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                                    Nurse Pat
                                    Participant

                                      What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

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                                        PeterS
                                        Participant

                                          Hi,

                                          I am fortunate that my rash is mild (nothing like Jonah's post on http://www.groinstrong.com 

                                          The whole time of the course I am prescribed Doxycycline (2x100mg).  Recently I got Pyridoxine (vit B6) (3x50mg).

                                          Every day I put on Diprobase all over the body  (sometimes twice a day for the parts with rash).  

                                          The hydrocortisone 1% cream didn't have much effect on me.  Now trying Clindamycin although such a small stick for that much surface is time consuming.

                                          About 3 weeks ago I had a rash on my scalp and got Elocon.  That stuff did wonders and cleared up the problem in a few days.  It dries out the skin, so I had to put Diprobase on the days I was treating it with Elocon.  Now that the problem is resolved, I now use Oilatum scalp shampoo and haven't had issues since.

                                          After working in the garden, I had cracked skin on two fingers which had bled.  Even though it was healing, the protocol seems to stipulate that I had to be taken off the drug for a week.  It was also unfortunate that I had two mouth ulcers which I was successfully treating with Bonjela.  It was unfortunate but they have to stick to the rules.  I now cream up my hands with Neutrogena cream almost every time after I wash them, and twice a day I use Corsodyl mouth wash.  The bottom of my feet and heels tend to get dry so I treat it with Scholl Cracked Heel Repair Cream if it starts to get worse, or otherwise with the regular Diprobase.

                                          Just to complete the list, I also use the Oilatum shower gel on my face especially as it is easier to make sure my ears are all greased up.

                                          Peter

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                                          PeterS
                                          Participant

                                            Hi,

                                            I am fortunate that my rash is mild (nothing like Jonah's post on http://www.groinstrong.com 

                                            The whole time of the course I am prescribed Doxycycline (2x100mg).  Recently I got Pyridoxine (vit B6) (3x50mg).

                                            Every day I put on Diprobase all over the body  (sometimes twice a day for the parts with rash).  

                                            The hydrocortisone 1% cream didn't have much effect on me.  Now trying Clindamycin although such a small stick for that much surface is time consuming.

                                            About 3 weeks ago I had a rash on my scalp and got Elocon.  That stuff did wonders and cleared up the problem in a few days.  It dries out the skin, so I had to put Diprobase on the days I was treating it with Elocon.  Now that the problem is resolved, I now use Oilatum scalp shampoo and haven't had issues since.

                                            After working in the garden, I had cracked skin on two fingers which had bled.  Even though it was healing, the protocol seems to stipulate that I had to be taken off the drug for a week.  It was also unfortunate that I had two mouth ulcers which I was successfully treating with Bonjela.  It was unfortunate but they have to stick to the rules.  I now cream up my hands with Neutrogena cream almost every time after I wash them, and twice a day I use Corsodyl mouth wash.  The bottom of my feet and heels tend to get dry so I treat it with Scholl Cracked Heel Repair Cream if it starts to get worse, or otherwise with the regular Diprobase.

                                            Just to complete the list, I also use the Oilatum shower gel on my face especially as it is easier to make sure my ears are all greased up.

                                            Peter

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                                          Nurse Pat
                                          Participant

                                            What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

                                            Loading spinner
                                            Nurse Pat
                                            Participant

                                              What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

                                              Loading spinner
                                              Nurse Pat
                                              Participant

                                                What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

                                                Loading spinner
                                                Nurse Pat
                                                Participant

                                                  What type of premedications do you take prior to taking the GSK1120212?  Do you take it everyday?   I hear the rash is the worst, but others say leg pains (arthralgias).

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