Quick rundown… 2004 Mole left ankle biopsy Melanoma 1.05 mm, Clark’s level IV, neg ulceration , miotic rate 2/mm2. I had a wide Excision and negative sentinel lymph node biopsy.
Jan 2011 new nodular lesion left shin area, melanoma
March 2011 wide excision and skin flap
Sept 2011 2 nodular looking lesions left shin area
Dec 2011 ILP MDAnderson with Melphalan and Dactamycian (I know I spelled that wrong sorry) not very successful .
May 2012 2 more lesions ..revealed dermal s100-positive spindle cell proliferation similar to the one seen in previous biopsy.
Dec 2012 Clinical Trial ILP with Temozolomide .. Unsuccessful, removed from trial and proceeded with 5 wide excisions and skin graft Feb 2013
March 2013 1month later finished skin graft on shin and had reexcision on 2 areas where the margins were not clear and skin graft on ankle where I found Sub Q?
May 2013 found new suspicious lesion left calf .. Referred to medical oncology at MDA
They had been talking about treatment with Zelboraf since I am BRAF positive, but I thought I understood it to be used as a last resort type of thing, and that people become resist to it after a short period of time. So far all my scans up until now are clear. So would another treatment be better before Z ?
I sure would appreciate any advice you have. It’s late and I’m tired and worried so I hope I haven’t confused anyone too much. Thanks ahead of time.
Dee
