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Good News PD-1
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Good News PD-1

› Forums › General Melanoma Community › Good News PD-1

  • Post
    • January 8, 2014 at 12:27 pm
    Lisa – Aust
    Participant

      Hi Everyone,

      Just wanted to share our good news and give others hope. My husband Craig started the Merck PD1 trial in Oct 2013 after prolonged success on the BRAF inhibitor trial. The one lymph node in his abdominal region flared up again, so he had to stop the BRAF trial. He had his first set of scans last week since starting the PD1 trial, and the results today were excellent. He had an 80% reduction in the size of his tumour. Although his tumour wasnt very big to begin with, the results are so encouraging, and it is such a relief that he is responding. This drug seems to be doing wonderful things, I hope everyone can have similar positive results.

      We are a couple of relieved Aussies tonight.

      Good luck to everyone fighting

      Lisa

      x

    Viewing 14 reply threads
    • Replies
        • January 8, 2014 at 2:32 pm
        Brendan
        Participant

          Great news, Lisa.  Thanks for sharing.  I fly to Florida on Friday for my second PD1 infusion.  Hopefully my wife and I will be celbrating soon as well.

          Brendan

            • January 8, 2014 at 6:50 pm
            Maureen038
            Participant

              That's such wonderful news Lisa!! Congratulations!

              • January 8, 2014 at 6:50 pm
              Maureen038
              Participant

                That's such wonderful news Lisa!! Congratulations!

                • January 8, 2014 at 6:50 pm
                Maureen038
                Participant

                  That's such wonderful news Lisa!! Congratulations!

                  • January 9, 2014 at 1:26 am
                  Lisa – Aust
                  Participant

                    Thanks Brendan, I have everything crossed for you!

                    All the best

                    • January 9, 2014 at 1:26 am
                    Lisa – Aust
                    Participant

                      Thanks Brendan, I have everything crossed for you!

                      All the best

                      • January 9, 2014 at 1:26 am
                      Lisa – Aust
                      Participant

                        Thanks Brendan, I have everything crossed for you!

                        All the best

                      • January 8, 2014 at 2:32 pm
                      Brendan
                      Participant

                        Great news, Lisa.  Thanks for sharing.  I fly to Florida on Friday for my second PD1 infusion.  Hopefully my wife and I will be celbrating soon as well.

                        Brendan

                        • January 8, 2014 at 2:32 pm
                        Brendan
                        Participant

                          Great news, Lisa.  Thanks for sharing.  I fly to Florida on Friday for my second PD1 infusion.  Hopefully my wife and I will be celbrating soon as well.

                          Brendan

                          • January 8, 2014 at 8:04 pm
                          Globetrotter
                          Participant

                            thanks for sharing this fantastic news with us, Lisa …  hope the anti-pd1 medication will keep doing wonderful things for Craig!!

                            • January 8, 2014 at 8:04 pm
                            Globetrotter
                            Participant

                              thanks for sharing this fantastic news with us, Lisa …  hope the anti-pd1 medication will keep doing wonderful things for Craig!!

                                • January 8, 2014 at 10:59 pm
                                sofistef
                                Participant
                                  It’s so good to see all these responses to pd1 treatment, this gives us hope.thanks for sharing.

                                  Dana

                                  • January 8, 2014 at 10:59 pm
                                  sofistef
                                  Participant
                                    It’s so good to see all these responses to pd1 treatment, this gives us hope.thanks for sharing.

                                    Dana

                                    • January 8, 2014 at 10:59 pm
                                    sofistef
                                    Participant
                                      It’s so good to see all these responses to pd1 treatment, this gives us hope.thanks for sharing.

                                      Dana

                                      • January 9, 2014 at 1:27 am
                                      Lisa – Aust
                                      Participant

                                        Thanks so much 🙂

                                        x

                                        • January 9, 2014 at 1:27 am
                                        Lisa – Aust
                                        Participant

                                          Thanks so much 🙂

                                          x

                                          • January 9, 2014 at 1:27 am
                                          Lisa – Aust
                                          Participant

                                            Thanks so much 🙂

                                            x

                                            • January 9, 2014 at 1:30 am
                                            Lisa – Aust
                                            Participant

                                              Thanks!

                                              • January 9, 2014 at 1:30 am
                                              Lisa – Aust
                                              Participant

                                                Thanks!

                                                • January 9, 2014 at 1:30 am
                                                Lisa – Aust
                                                Participant

                                                  Thanks!

                                                • January 8, 2014 at 8:04 pm
                                                Globetrotter
                                                Participant

                                                  thanks for sharing this fantastic news with us, Lisa …  hope the anti-pd1 medication will keep doing wonderful things for Craig!!

                                                  • January 8, 2014 at 11:53 pm
                                                  benp
                                                  Participant

                                                    Happy to hear that Lisa – I know how hard it is to get on MK3475 in Australia – fortunately I'm part of a trial at Westmead (Sydney). Just had 24 week scans, all looking relatively good!

                                                     

                                                    Ben.

                                                    • January 8, 2014 at 11:53 pm
                                                    benp
                                                    Participant

                                                      Happy to hear that Lisa – I know how hard it is to get on MK3475 in Australia – fortunately I'm part of a trial at Westmead (Sydney). Just had 24 week scans, all looking relatively good!

                                                       

                                                      Ben.

                                                      • January 8, 2014 at 11:53 pm
                                                      benp
                                                      Participant

                                                        Happy to hear that Lisa – I know how hard it is to get on MK3475 in Australia – fortunately I'm part of a trial at Westmead (Sydney). Just had 24 week scans, all looking relatively good!

                                                         

                                                        Ben.

                                                          • January 9, 2014 at 1:30 am
                                                          Lisa – Aust
                                                          Participant

                                                            Hi Ben,

                                                            So great to hear your news. How are you tolerating the drug? Yep, Craig has been extraordinarily lucky on many fronts. We are over in Perth and he was first in WA on the B-RAF trial, and he was also first in WA on the PD-1 trial! We had to wait about 9 weeksfor it to start, which was a bit of a tense wait, but absolutely worth it. He has timed things pretty well!

                                                            Hopefully many can have access to this drug sooner than later.

                                                            Good luck 

                                                            • January 9, 2014 at 1:30 am
                                                            Lisa – Aust
                                                            Participant

                                                              Hi Ben,

                                                              So great to hear your news. How are you tolerating the drug? Yep, Craig has been extraordinarily lucky on many fronts. We are over in Perth and he was first in WA on the B-RAF trial, and he was also first in WA on the PD-1 trial! We had to wait about 9 weeksfor it to start, which was a bit of a tense wait, but absolutely worth it. He has timed things pretty well!

                                                              Hopefully many can have access to this drug sooner than later.

                                                              Good luck 

                                                              • January 9, 2014 at 7:28 am
                                                              deardad
                                                              Participant

                                                                Lisa thats wonderful news…so happy to hear that things are going well for Craig.

                                                                BENP great to hear that the trial is working for you too.

                                                                Always in my thoughts.

                                                                Nahmi from Melbourne

                                                                • January 9, 2014 at 7:28 am
                                                                deardad
                                                                Participant

                                                                  Lisa thats wonderful news…so happy to hear that things are going well for Craig.

                                                                  BENP great to hear that the trial is working for you too.

                                                                  Always in my thoughts.

                                                                  Nahmi from Melbourne

                                                                  • January 10, 2014 at 5:00 am
                                                                  Lisa – Aust
                                                                  Participant

                                                                    Thanks Nahmi – I hope you are going ok x

                                                                    • January 10, 2014 at 5:00 am
                                                                    Lisa – Aust
                                                                    Participant

                                                                      Thanks Nahmi – I hope you are going ok x

                                                                      • January 10, 2014 at 5:00 am
                                                                      Lisa – Aust
                                                                      Participant

                                                                        Thanks Nahmi – I hope you are going ok x

                                                                        • January 9, 2014 at 7:28 am
                                                                        deardad
                                                                        Participant

                                                                          Lisa thats wonderful news…so happy to hear that things are going well for Craig.

                                                                          BENP great to hear that the trial is working for you too.

                                                                          Always in my thoughts.

                                                                          Nahmi from Melbourne

                                                                          • January 9, 2014 at 1:30 am
                                                                          Lisa – Aust
                                                                          Participant

                                                                            Hi Ben,

                                                                            So great to hear your news. How are you tolerating the drug? Yep, Craig has been extraordinarily lucky on many fronts. We are over in Perth and he was first in WA on the B-RAF trial, and he was also first in WA on the PD-1 trial! We had to wait about 9 weeksfor it to start, which was a bit of a tense wait, but absolutely worth it. He has timed things pretty well!

                                                                            Hopefully many can have access to this drug sooner than later.

                                                                            Good luck 

                                                                          • January 9, 2014 at 1:19 pm
                                                                          Tina D
                                                                          Participant

                                                                            WOW!! 80% is awesome! Congratulations on this wonderful response 🙂

                                                                            Thanks for sharing, too… a little encouragement is always nice right before scans 🙂

                                                                            Heading for third PD1 scans this weekend…

                                                                            Tina

                                                                            • January 9, 2014 at 1:19 pm
                                                                            Tina D
                                                                            Participant

                                                                              WOW!! 80% is awesome! Congratulations on this wonderful response 🙂

                                                                              Thanks for sharing, too… a little encouragement is always nice right before scans 🙂

                                                                              Heading for third PD1 scans this weekend…

                                                                              Tina

                                                                              • January 9, 2014 at 1:19 pm
                                                                              Tina D
                                                                              Participant

                                                                                WOW!! 80% is awesome! Congratulations on this wonderful response 🙂

                                                                                Thanks for sharing, too… a little encouragement is always nice right before scans 🙂

                                                                                Heading for third PD1 scans this weekend…

                                                                                Tina

                                                                                  • January 10, 2014 at 1:16 am
                                                                                  UrsulaZ
                                                                                  Participant

                                                                                    Lisa, that's amazing. Congratuations to both of you!!!!

                                                                                    Is he tolerating it without too many side effects? 

                                                                                    -Ursula

                                                                                    • January 10, 2014 at 1:16 am
                                                                                    UrsulaZ
                                                                                    Participant

                                                                                      Lisa, that's amazing. Congratuations to both of you!!!!

                                                                                      Is he tolerating it without too many side effects? 

                                                                                      -Ursula

                                                                                      • January 10, 2014 at 1:16 am
                                                                                      UrsulaZ
                                                                                      Participant

                                                                                        Lisa, that's amazing. Congratuations to both of you!!!!

                                                                                        Is he tolerating it without too many side effects? 

                                                                                        -Ursula

                                                                                        • January 10, 2014 at 5:12 am
                                                                                        Lisa – Aust
                                                                                        Participant

                                                                                          Hi Ursula,

                                                                                          Thanks, it was a lovely result to get after the extreme anxiety we had going into the scan! This was probably the worst we have felt.

                                                                                          Yes, he is tolerating it very well. He is quite a 'stoic' type of guy when it comes to how he feels physically. He is either 'fine' or really sick – no middle ground! So often he will say he's ok, but I can see he is more tired than usual and will need to have a nap. But for the most part its life as usual in terms of work, uni, exercise etc. He did have a reaction to the 2nd or 3rd infusion – had the rigors immediately after. But we both had a stomach bug the day before and were pretty ill – so I think that contributed. They give him some pre-meds now to prevent that happening again.

                                                                                          I see from your latest blog post that you continue to have a good response too! That is just fantastic. Its nice to have some breathing room hey.

                                                                                          Are you experiencing many side effects?

                                                                                          Lisa x

                                                                                          • January 10, 2014 at 5:12 am
                                                                                          Lisa – Aust
                                                                                          Participant

                                                                                            Hi Ursula,

                                                                                            Thanks, it was a lovely result to get after the extreme anxiety we had going into the scan! This was probably the worst we have felt.

                                                                                            Yes, he is tolerating it very well. He is quite a 'stoic' type of guy when it comes to how he feels physically. He is either 'fine' or really sick – no middle ground! So often he will say he's ok, but I can see he is more tired than usual and will need to have a nap. But for the most part its life as usual in terms of work, uni, exercise etc. He did have a reaction to the 2nd or 3rd infusion – had the rigors immediately after. But we both had a stomach bug the day before and were pretty ill – so I think that contributed. They give him some pre-meds now to prevent that happening again.

                                                                                            I see from your latest blog post that you continue to have a good response too! That is just fantastic. Its nice to have some breathing room hey.

                                                                                            Are you experiencing many side effects?

                                                                                            Lisa x

                                                                                            • January 10, 2014 at 5:12 am
                                                                                            Lisa – Aust
                                                                                            Participant

                                                                                              Hi Ursula,

                                                                                              Thanks, it was a lovely result to get after the extreme anxiety we had going into the scan! This was probably the worst we have felt.

                                                                                              Yes, he is tolerating it very well. He is quite a 'stoic' type of guy when it comes to how he feels physically. He is either 'fine' or really sick – no middle ground! So often he will say he's ok, but I can see he is more tired than usual and will need to have a nap. But for the most part its life as usual in terms of work, uni, exercise etc. He did have a reaction to the 2nd or 3rd infusion – had the rigors immediately after. But we both had a stomach bug the day before and were pretty ill – so I think that contributed. They give him some pre-meds now to prevent that happening again.

                                                                                              I see from your latest blog post that you continue to have a good response too! That is just fantastic. Its nice to have some breathing room hey.

                                                                                              Are you experiencing many side effects?

                                                                                              Lisa x

                                                                                              • January 10, 2014 at 5:03 am
                                                                                              Lisa – Aust
                                                                                              Participant

                                                                                                Hi Tina,

                                                                                                Thanks – I know what you mean. The night before the results I was trawling the net for positive stories to calm myself. Hope this news helps a few.

                                                                                                All the best for your scan – I will be thinking of you.

                                                                                                Let us know how you go

                                                                                                x

                                                                                                • January 10, 2014 at 5:13 am
                                                                                                Lisa – Aust
                                                                                                Participant

                                                                                                  THANK YOU to everyone for your kind replies. I have tried to thank each of you, but it doesnt seem to be flowing right!

                                                                                                  Cheers 

                                                                                                  • January 10, 2014 at 5:13 am
                                                                                                  Lisa – Aust
                                                                                                  Participant

                                                                                                    THANK YOU to everyone for your kind replies. I have tried to thank each of you, but it doesnt seem to be flowing right!

                                                                                                    Cheers 

                                                                                                    • January 10, 2014 at 5:13 am
                                                                                                    Lisa – Aust
                                                                                                    Participant

                                                                                                      THANK YOU to everyone for your kind replies. I have tried to thank each of you, but it doesnt seem to be flowing right!

                                                                                                      Cheers 

                                                                                                      • January 10, 2014 at 5:03 am
                                                                                                      Lisa – Aust
                                                                                                      Participant

                                                                                                        Hi Tina,

                                                                                                        Thanks – I know what you mean. The night before the results I was trawling the net for positive stories to calm myself. Hope this news helps a few.

                                                                                                        All the best for your scan – I will be thinking of you.

                                                                                                        Let us know how you go

                                                                                                        x

                                                                                                        • January 10, 2014 at 5:03 am
                                                                                                        Lisa – Aust
                                                                                                        Participant

                                                                                                          Hi Tina,

                                                                                                          Thanks – I know what you mean. The night before the results I was trawling the net for positive stories to calm myself. Hope this news helps a few.

                                                                                                          All the best for your scan – I will be thinking of you.

                                                                                                          Let us know how you go

                                                                                                          x

                                                                                                        • January 11, 2014 at 4:31 am
                                                                                                        Jahendry12
                                                                                                        Participant

                                                                                                          Awesome News Lisa!!!!  So so happy for you and your husband. Please keep us posted. 

                                                                                                          • January 11, 2014 at 4:31 am
                                                                                                          Jahendry12
                                                                                                          Participant

                                                                                                            Awesome News Lisa!!!!  So so happy for you and your husband. Please keep us posted. 

                                                                                                            • January 11, 2014 at 4:31 am
                                                                                                            Jahendry12
                                                                                                            Participant

                                                                                                              Awesome News Lisa!!!!  So so happy for you and your husband. Please keep us posted. 

                                                                                                          Viewing 14 reply threads
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