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Expanded Access Program MK-3475 – mayo status
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Expanded Access Program MK-3475 – mayo status

› Forums › General Melanoma Community › Expanded Access Program MK-3475 – mayo status

  • Post
    • May 23, 2014 at 5:14 pm
    arthurjedi007
    Participant

      Here's the scoop from my experience at Mayo for Merck's EAP of their MK-3475 PD1.

      Took about a week for them to do the paper work.

      They were told it would take about a week to get the medicine but they got it within a day or two.

      Had to have a little over a week washout period for the Taf/Mek combo.

      The dosage is 2 mg per kg of your weight. Administered by iv over 30 minutes every 3 weeks.

      Merck has allocated 4500 slots. 100 have been allocated to Mayo and they have filled 42 of them.

      If this trial becomes available closer to home they can transfer you.

      Here's the trial number if you are interested: NCT02083484

      I started it last Wednesday.

    Viewing 29 reply threads
    • Replies
        • May 23, 2014 at 8:33 pm
        POW
        Participant

          Whoo hoo, Artie! You made it! Congratulations! You are one tough, determined bugger, aren't you?!

          I will be praying and praying that the MK-3475 kicks mel's butt for you. You sure have earned a success. Is Mayo your closest facility or are you hoping that the EAP comes to some place closer to you?

          • May 23, 2014 at 8:33 pm
          POW
          Participant

            Whoo hoo, Artie! You made it! Congratulations! You are one tough, determined bugger, aren't you?!

            I will be praying and praying that the MK-3475 kicks mel's butt for you. You sure have earned a success. Is Mayo your closest facility or are you hoping that the EAP comes to some place closer to you?

            • May 23, 2014 at 8:33 pm
            POW
            Participant

              Whoo hoo, Artie! You made it! Congratulations! You are one tough, determined bugger, aren't you?!

              I will be praying and praying that the MK-3475 kicks mel's butt for you. You sure have earned a success. Is Mayo your closest facility or are you hoping that the EAP comes to some place closer to you?

              • May 23, 2014 at 9:05 pm
              Tina D
              Participant

                This is super great news.. also, I am sure the details will be incredibly helpful for those needing the EAP for PD1.

                So glad you were able to get access and get started so quickly!

                Tina

                • May 23, 2014 at 9:05 pm
                Tina D
                Participant

                  This is super great news.. also, I am sure the details will be incredibly helpful for those needing the EAP for PD1.

                  So glad you were able to get access and get started so quickly!

                  Tina

                  • May 23, 2014 at 9:05 pm
                  Tina D
                  Participant

                    This is super great news.. also, I am sure the details will be incredibly helpful for those needing the EAP for PD1.

                    So glad you were able to get access and get started so quickly!

                    Tina

                    • May 23, 2014 at 9:34 pm
                    evleye
                    Participant

                      Sending positive thoughts for success with this trial and no side effects (well very little anyway)!!

                      • May 23, 2014 at 9:34 pm
                      evleye
                      Participant

                        Sending positive thoughts for success with this trial and no side effects (well very little anyway)!!

                        • May 23, 2014 at 9:34 pm
                        evleye
                        Participant

                          Sending positive thoughts for success with this trial and no side effects (well very little anyway)!!

                            • May 23, 2014 at 11:18 pm
                            tschmith
                            Participant

                              Prayng that it works for you, Artie!  You are a real fighter and your posts have inspired me when I'm feeling down in the dumps.  Best wishes to you!

                              Terrie

                              • May 23, 2014 at 11:18 pm
                              tschmith
                              Participant

                                Prayng that it works for you, Artie!  You are a real fighter and your posts have inspired me when I'm feeling down in the dumps.  Best wishes to you!

                                Terrie

                                • May 23, 2014 at 11:18 pm
                                tschmith
                                Participant

                                  Prayng that it works for you, Artie!  You are a real fighter and your posts have inspired me when I'm feeling down in the dumps.  Best wishes to you!

                                  Terrie

                                • May 24, 2014 at 12:44 am
                                Bubbles
                                Participant

                                  Congrats, Artie!  Wishing you my best!  Celeste

                                  • May 24, 2014 at 12:44 am
                                  Bubbles
                                  Participant

                                    Congrats, Artie!  Wishing you my best!  Celeste

                                    • May 24, 2014 at 12:44 am
                                    Bubbles
                                    Participant

                                      Congrats, Artie!  Wishing you my best!  Celeste

                                      • May 24, 2014 at 10:03 am
                                      Mat
                                      Participant

                                        Great news Artie!

                                        • May 24, 2014 at 10:03 am
                                        Mat
                                        Participant

                                          Great news Artie!

                                          • May 24, 2014 at 10:03 am
                                          Mat
                                          Participant

                                            Great news Artie!

                                            • May 24, 2014 at 3:55 pm
                                            BrianP
                                            Participant

                                              Great news Artie!  Way to persevere.

                                              Brian

                                              • May 24, 2014 at 3:55 pm
                                              BrianP
                                              Participant

                                                Great news Artie!  Way to persevere.

                                                Brian

                                                • May 24, 2014 at 3:55 pm
                                                BrianP
                                                Participant

                                                  Great news Artie!  Way to persevere.

                                                  Brian

                                                  • May 24, 2014 at 6:35 pm
                                                  arthurjedi007
                                                  Participant

                                                    Thank you all for well everything. I couldn't have made it this far without the support and information I have found here.

                                                    Yes Mayo is about 1000 miles round trip for us. But mom packed lots of food and dad made sure the car was checked out so we did fine. If I don't have at least a bananna or something every couple hours I get weak so mom likes to make sure there is plenty to eat. There was also an old country buffet resteraunt up there so I ate really good. There is no direct flight so I added it up and it would take about the same amount of time to fly and mom preferred to drive.

                                                    When I was at Siteman here in Saint Louis almost 4 weeks ago they said they had started the paperwork and should have it here within a month. I doubt they will be that fast but maybe and I assume eventually it will be here. They prefer BMS so they might concentrate their time on it's EAP instead. I dunno. I'm supposed to go to Siteman this Tuesday if Mayo says it is ok to continue with the Xgeva shot so I should learn more. That will be easier if it was here but it was a nice trip to Mayo. That Kalar Grand hotel was nice there and right across the street.

                                                     

                                                    • May 24, 2014 at 6:35 pm
                                                    arthurjedi007
                                                    Participant

                                                      Thank you all for well everything. I couldn't have made it this far without the support and information I have found here.

                                                      Yes Mayo is about 1000 miles round trip for us. But mom packed lots of food and dad made sure the car was checked out so we did fine. If I don't have at least a bananna or something every couple hours I get weak so mom likes to make sure there is plenty to eat. There was also an old country buffet resteraunt up there so I ate really good. There is no direct flight so I added it up and it would take about the same amount of time to fly and mom preferred to drive.

                                                      When I was at Siteman here in Saint Louis almost 4 weeks ago they said they had started the paperwork and should have it here within a month. I doubt they will be that fast but maybe and I assume eventually it will be here. They prefer BMS so they might concentrate their time on it's EAP instead. I dunno. I'm supposed to go to Siteman this Tuesday if Mayo says it is ok to continue with the Xgeva shot so I should learn more. That will be easier if it was here but it was a nice trip to Mayo. That Kalar Grand hotel was nice there and right across the street.

                                                       

                                                        • May 25, 2014 at 12:50 am
                                                        BrianP
                                                        Participant

                                                          1000 miles!  That's a pretty good haul.  My treatments are a little over 600 miles round trip and I thought that was long.  But it's like I always say to people that comment on it, "It's a small price to pay for the gift of hope."

                                                          • May 25, 2014 at 12:50 am
                                                          BrianP
                                                          Participant

                                                            1000 miles!  That's a pretty good haul.  My treatments are a little over 600 miles round trip and I thought that was long.  But it's like I always say to people that comment on it, "It's a small price to pay for the gift of hope."

                                                            • May 25, 2014 at 12:50 am
                                                            BrianP
                                                            Participant

                                                              1000 miles!  That's a pretty good haul.  My treatments are a little over 600 miles round trip and I thought that was long.  But it's like I always say to people that comment on it, "It's a small price to pay for the gift of hope."

                                                            • May 24, 2014 at 6:35 pm
                                                            arthurjedi007
                                                            Participant

                                                              Thank you all for well everything. I couldn't have made it this far without the support and information I have found here.

                                                              Yes Mayo is about 1000 miles round trip for us. But mom packed lots of food and dad made sure the car was checked out so we did fine. If I don't have at least a bananna or something every couple hours I get weak so mom likes to make sure there is plenty to eat. There was also an old country buffet resteraunt up there so I ate really good. There is no direct flight so I added it up and it would take about the same amount of time to fly and mom preferred to drive.

                                                              When I was at Siteman here in Saint Louis almost 4 weeks ago they said they had started the paperwork and should have it here within a month. I doubt they will be that fast but maybe and I assume eventually it will be here. They prefer BMS so they might concentrate their time on it's EAP instead. I dunno. I'm supposed to go to Siteman this Tuesday if Mayo says it is ok to continue with the Xgeva shot so I should learn more. That will be easier if it was here but it was a nice trip to Mayo. That Kalar Grand hotel was nice there and right across the street.

                                                               

                                                              • May 25, 2014 at 1:39 am
                                                              POW
                                                              Participant

                                                                Artie, did you see the recent post about the "Corporate Angel Network"? Brian, you too. They offer free rides on corporate jets to cancer patients. Why don't you give them a call? Here's the link http://www.corpangelnetwork.org/about/index.html Even if they can only take you once in a while it would probably be a welcome change from such long drives.

                                                                • May 25, 2014 at 1:39 am
                                                                POW
                                                                Participant

                                                                  Artie, did you see the recent post about the "Corporate Angel Network"? Brian, you too. They offer free rides on corporate jets to cancer patients. Why don't you give them a call? Here's the link http://www.corpangelnetwork.org/about/index.html Even if they can only take you once in a while it would probably be a welcome change from such long drives.

                                                                  • May 25, 2014 at 1:39 am
                                                                  POW
                                                                  Participant

                                                                    Artie, did you see the recent post about the "Corporate Angel Network"? Brian, you too. They offer free rides on corporate jets to cancer patients. Why don't you give them a call? Here's the link http://www.corpangelnetwork.org/about/index.html Even if they can only take you once in a while it would probably be a welcome change from such long drives.

                                                                    • May 25, 2014 at 1:51 am
                                                                    shanemcdonald99
                                                                    Participant

                                                                      Thats great to hear Artie !

                                                                      I wish you the best and may you respond well to the trial !

                                                                       

                                                                      blessings

                                                                      Shane

                                                                      • May 25, 2014 at 1:51 am
                                                                      shanemcdonald99
                                                                      Participant

                                                                        Thats great to hear Artie !

                                                                        I wish you the best and may you respond well to the trial !

                                                                         

                                                                        blessings

                                                                        Shane

                                                                        • May 25, 2014 at 1:51 am
                                                                        shanemcdonald99
                                                                        Participant

                                                                          Thats great to hear Artie !

                                                                          I wish you the best and may you respond well to the trial !

                                                                           

                                                                          blessings

                                                                          Shane

                                                                          • May 26, 2014 at 2:27 pm
                                                                          LuckyMan51
                                                                          Participant

                                                                            Congratulations Artie, Been following your posts and am very impressed in your analysis and decision making. You are extremely tenacious in your attack on this disease and are inspirational as far as an individual making their own good luck. Wishing you all the best and look forward to the post when you inform us of your NED status. 

                                                                            • May 26, 2014 at 2:27 pm
                                                                            LuckyMan51
                                                                            Participant

                                                                              Congratulations Artie, Been following your posts and am very impressed in your analysis and decision making. You are extremely tenacious in your attack on this disease and are inspirational as far as an individual making their own good luck. Wishing you all the best and look forward to the post when you inform us of your NED status. 

                                                                              • May 26, 2014 at 2:27 pm
                                                                              LuckyMan51
                                                                              Participant

                                                                                Congratulations Artie, Been following your posts and am very impressed in your analysis and decision making. You are extremely tenacious in your attack on this disease and are inspirational as far as an individual making their own good luck. Wishing you all the best and look forward to the post when you inform us of your NED status. 

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