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Dr. O’Day short talk on immune checkpoint inhibition / Advanced melanoma

Forums General Melanoma Community Dr. O’Day short talk on immune checkpoint inhibition / Advanced melanoma

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      BrianP
      Participant

        Thanks Chris.  I thought his figures sounded pretty close.  Hope your treatment is going well.

        BrianP
        Participant

          Thanks Chris.  I thought his figures sounded pretty close.  Hope your treatment is going well.

          BrianP
          Participant

            Thanks Chris.  I thought his figures sounded pretty close.  Hope your treatment is going well.

              tcell
              Participant

                Hi Brian,

                good to read from you. My therapy seems to be going ok. I saw a specialist on complementary medicine this week who had all kinds of ideas what we could try but we decided we were going to wait for the first scans in May. Started to take vitamin D and K.

                What are you doing apart from your therapy like diet or alternative methods?

                How is your trial going?

                BrianP
                Participant

                  Boy Chris. That is the 64,000 dollar question (or should I say 64,000 euro question). I have made some significant changes to my life style since my stage III diagnosis in 2011. Having said that I really can't claim that I've found the key to it all since I obviously progressed to stage IV and have had some recent setbacks but I guess I'm still here so maybe I"m not doing everything wrong.

                  I read a book early on that had a pretty big influence on me. It's a book call "Anti-Cancer, A New way of Life" by David Servan Schreiber. I thought it was a great book, especially for anyone just starting this battle. I also watched a documentary called Forks Over Knifes which also had a big influence on my eating habits. I haven't gone totally vegetarian but only have chicken or fish a few times a week and most everything else is fruits, vegetables, and nuts. Dairy intake has been reduced (mostly by not drinking milk anymore). I've tried to cut out as much sugar as possible. That was tough in the beginning because I did have a pretty big sweet tooth but I hardly miss the sugar anymore. I do a smoothie of fruits, vegetables, and greek yogurt just about every day. I also have 2 cups of green tea just about everyday. I exercise about 5 – 6 times a week. My goal is to get my heart rate up to around the 140 bpm range for at least 45 minutes. I had a eye opening experience last year on how exercise can impact your WBC production so I really put a big value on exercise.

                  The supplement plan is where I've had the most difficulty coming up with a plan I am confident in. Over the course of the last couple years for the majority of the time of taken curcumin, D3, COQ10, and resvertrol. Those are all pretty standard cancer fighting supplements. For some time I was taking some supplements by a brand named "Enriching Gifts". This product line was recommended to me by a naturopath and I was taking some of their multi-purpose vitamins, plant enzymes, and sterol max (another plant derivative). The founder of that line is real big on enzymes which I think Europe is a lot further along than we are in that field. Just recently I had a phone consult with a Dr. from San Francisco. I have a lot of respect for this particular Dr. and he gave me three recommendations for supplements: Melatonin, NAC, and resvertrol. I'll probably be starting the melatonin and NAC very soon. I havn't heard of vitamin K before. I'll have to look that one up.

                  You probably weren't expecting that long of an answer. I'm doing pretty good on my trial right now. I recently posted here about some encouraging results as of late: 

                  http://www.melanoma.org/find-support/patient-community/mpip-melanoma-patients-information-page/tumors-no-fdg-uptake-pet

                  Brian

                   

                  Mat
                  Participant

                    Just echoing Brian's recommendation of Anti-Cancer, which covers much more ground than diet.  I'd also recommend "Not the Last Goodbye" by the same author.  To the extent that folks are looking for assistance with their mindset, these are great books.  (Disclosure: Unfortunately, the author did not survive his (brain) cancer, but he enjoyed a lengthy (10 year) remission.) 

                    Mat
                    Participant

                      Just echoing Brian's recommendation of Anti-Cancer, which covers much more ground than diet.  I'd also recommend "Not the Last Goodbye" by the same author.  To the extent that folks are looking for assistance with their mindset, these are great books.  (Disclosure: Unfortunately, the author did not survive his (brain) cancer, but he enjoyed a lengthy (10 year) remission.) 

                      tcell
                      Participant

                        I thought he lived for 20 years after his diagnosis! 

                        tcell
                        Participant

                          I thought he lived for 20 years after his diagnosis! 

                          tcell
                          Participant

                            I thought he lived for 20 years after his diagnosis! 

                            Mat
                            Participant

                              Just echoing Brian's recommendation of Anti-Cancer, which covers much more ground than diet.  I'd also recommend "Not the Last Goodbye" by the same author.  To the extent that folks are looking for assistance with their mindset, these are great books.  (Disclosure: Unfortunately, the author did not survive his (brain) cancer, but he enjoyed a lengthy (10 year) remission.) 

                              tcell
                              Participant

                                Hi Brian,

                                First of all I am very happy for you that the treatment with those 2 promising meds seems to do a good job for you. Keeping fingers crossed for a long lasting reponse!

                                thanks for your long answer on nutrition. I have read that book and I agree that it is a very good source of information. So I guess we are pretty much on the same diet. The only thing that I could not get through to is to have a smoothie. I was recommended to do that but it just seems strange to me…a few months ago I had a cold beer, now I am having green cabbage??? BTW I am now also using barley grass powder which kind of does the same as green vegetables, worh the advantage that it is easier to cover your daily needs than eating a pound of cabbage:

                                http://www.purehealingfoods.com/barleyGrassInfo.php

                                you can either use the powder to mix a few teaspoons into your soup or smoothie or also get it in capsules.

                                Otherwise I am also using vitamin d3, and vitamin K.

                                and one glass of red wine per day, one piece of dark chocolate are probably the most fun parts of my healthy diet.

                                and then, sometimes there are those days where I just throw a steak on the BBQ and have a cold beer with it, just because I need to feel that I am alive having fun!

                                happy easter!

                                Take care,

                                C

                                tcell
                                Participant

                                  Hi Brian,

                                  First of all I am very happy for you that the treatment with those 2 promising meds seems to do a good job for you. Keeping fingers crossed for a long lasting reponse!

                                  thanks for your long answer on nutrition. I have read that book and I agree that it is a very good source of information. So I guess we are pretty much on the same diet. The only thing that I could not get through to is to have a smoothie. I was recommended to do that but it just seems strange to me…a few months ago I had a cold beer, now I am having green cabbage??? BTW I am now also using barley grass powder which kind of does the same as green vegetables, worh the advantage that it is easier to cover your daily needs than eating a pound of cabbage:

                                  http://www.purehealingfoods.com/barleyGrassInfo.php

                                  you can either use the powder to mix a few teaspoons into your soup or smoothie or also get it in capsules.

                                  Otherwise I am also using vitamin d3, and vitamin K.

                                  and one glass of red wine per day, one piece of dark chocolate are probably the most fun parts of my healthy diet.

                                  and then, sometimes there are those days where I just throw a steak on the BBQ and have a cold beer with it, just because I need to feel that I am alive having fun!

                                  happy easter!

                                  Take care,

                                  C

                                  BrianP
                                  Participant

                                    Awesome Chris.  For a while I was juicing wheatgrass.  My Dad was actually growing it and I was juicing and drinking it. Eventually had to cry uncle.  It just tasted so bad I couldn't keep up the routine.  I have taken wheatgrass powder pills which are much easier to swallow.  Probably similar to your barley grass powder.

                                    BrianP
                                    Participant

                                      Awesome Chris.  For a while I was juicing wheatgrass.  My Dad was actually growing it and I was juicing and drinking it. Eventually had to cry uncle.  It just tasted so bad I couldn't keep up the routine.  I have taken wheatgrass powder pills which are much easier to swallow.  Probably similar to your barley grass powder.

                                      BrianP
                                      Participant

                                        Awesome Chris.  For a while I was juicing wheatgrass.  My Dad was actually growing it and I was juicing and drinking it. Eventually had to cry uncle.  It just tasted so bad I couldn't keep up the routine.  I have taken wheatgrass powder pills which are much easier to swallow.  Probably similar to your barley grass powder.

                                        tcell
                                        Participant

                                          Hi Brian,

                                          First of all I am very happy for you that the treatment with those 2 promising meds seems to do a good job for you. Keeping fingers crossed for a long lasting reponse!

                                          thanks for your long answer on nutrition. I have read that book and I agree that it is a very good source of information. So I guess we are pretty much on the same diet. The only thing that I could not get through to is to have a smoothie. I was recommended to do that but it just seems strange to me…a few months ago I had a cold beer, now I am having green cabbage??? BTW I am now also using barley grass powder which kind of does the same as green vegetables, worh the advantage that it is easier to cover your daily needs than eating a pound of cabbage:

                                          http://www.purehealingfoods.com/barleyGrassInfo.php

                                          you can either use the powder to mix a few teaspoons into your soup or smoothie or also get it in capsules.

                                          Otherwise I am also using vitamin d3, and vitamin K.

                                          and one glass of red wine per day, one piece of dark chocolate are probably the most fun parts of my healthy diet.

                                          and then, sometimes there are those days where I just throw a steak on the BBQ and have a cold beer with it, just because I need to feel that I am alive having fun!

                                          happy easter!

                                          Take care,

                                          C

                                          BrianP
                                          Participant

                                            Boy Chris. That is the 64,000 dollar question (or should I say 64,000 euro question). I have made some significant changes to my life style since my stage III diagnosis in 2011. Having said that I really can't claim that I've found the key to it all since I obviously progressed to stage IV and have had some recent setbacks but I guess I'm still here so maybe I"m not doing everything wrong.

                                            I read a book early on that had a pretty big influence on me. It's a book call "Anti-Cancer, A New way of Life" by David Servan Schreiber. I thought it was a great book, especially for anyone just starting this battle. I also watched a documentary called Forks Over Knifes which also had a big influence on my eating habits. I haven't gone totally vegetarian but only have chicken or fish a few times a week and most everything else is fruits, vegetables, and nuts. Dairy intake has been reduced (mostly by not drinking milk anymore). I've tried to cut out as much sugar as possible. That was tough in the beginning because I did have a pretty big sweet tooth but I hardly miss the sugar anymore. I do a smoothie of fruits, vegetables, and greek yogurt just about every day. I also have 2 cups of green tea just about everyday. I exercise about 5 – 6 times a week. My goal is to get my heart rate up to around the 140 bpm range for at least 45 minutes. I had a eye opening experience last year on how exercise can impact your WBC production so I really put a big value on exercise.

                                            The supplement plan is where I've had the most difficulty coming up with a plan I am confident in. Over the course of the last couple years for the majority of the time of taken curcumin, D3, COQ10, and resvertrol. Those are all pretty standard cancer fighting supplements. For some time I was taking some supplements by a brand named "Enriching Gifts". This product line was recommended to me by a naturopath and I was taking some of their multi-purpose vitamins, plant enzymes, and sterol max (another plant derivative). The founder of that line is real big on enzymes which I think Europe is a lot further along than we are in that field. Just recently I had a phone consult with a Dr. from San Francisco. I have a lot of respect for this particular Dr. and he gave me three recommendations for supplements: Melatonin, NAC, and resvertrol. I'll probably be starting the melatonin and NAC very soon. I havn't heard of vitamin K before. I'll have to look that one up.

                                            You probably weren't expecting that long of an answer. I'm doing pretty good on my trial right now. I recently posted here about some encouraging results as of late: 

                                            http://www.melanoma.org/find-support/patient-community/mpip-melanoma-patients-information-page/tumors-no-fdg-uptake-pet

                                            Brian

                                             

                                            BrianP
                                            Participant

                                              Boy Chris. That is the 64,000 dollar question (or should I say 64,000 euro question). I have made some significant changes to my life style since my stage III diagnosis in 2011. Having said that I really can't claim that I've found the key to it all since I obviously progressed to stage IV and have had some recent setbacks but I guess I'm still here so maybe I"m not doing everything wrong.

                                              I read a book early on that had a pretty big influence on me. It's a book call "Anti-Cancer, A New way of Life" by David Servan Schreiber. I thought it was a great book, especially for anyone just starting this battle. I also watched a documentary called Forks Over Knifes which also had a big influence on my eating habits. I haven't gone totally vegetarian but only have chicken or fish a few times a week and most everything else is fruits, vegetables, and nuts. Dairy intake has been reduced (mostly by not drinking milk anymore). I've tried to cut out as much sugar as possible. That was tough in the beginning because I did have a pretty big sweet tooth but I hardly miss the sugar anymore. I do a smoothie of fruits, vegetables, and greek yogurt just about every day. I also have 2 cups of green tea just about everyday. I exercise about 5 – 6 times a week. My goal is to get my heart rate up to around the 140 bpm range for at least 45 minutes. I had a eye opening experience last year on how exercise can impact your WBC production so I really put a big value on exercise.

                                              The supplement plan is where I've had the most difficulty coming up with a plan I am confident in. Over the course of the last couple years for the majority of the time of taken curcumin, D3, COQ10, and resvertrol. Those are all pretty standard cancer fighting supplements. For some time I was taking some supplements by a brand named "Enriching Gifts". This product line was recommended to me by a naturopath and I was taking some of their multi-purpose vitamins, plant enzymes, and sterol max (another plant derivative). The founder of that line is real big on enzymes which I think Europe is a lot further along than we are in that field. Just recently I had a phone consult with a Dr. from San Francisco. I have a lot of respect for this particular Dr. and he gave me three recommendations for supplements: Melatonin, NAC, and resvertrol. I'll probably be starting the melatonin and NAC very soon. I havn't heard of vitamin K before. I'll have to look that one up.

                                              You probably weren't expecting that long of an answer. I'm doing pretty good on my trial right now. I recently posted here about some encouraging results as of late: 

                                              http://www.melanoma.org/find-support/patient-community/mpip-melanoma-patients-information-page/tumors-no-fdg-uptake-pet

                                              Brian

                                               

                                              tcell
                                              Participant

                                                Hi Brian,

                                                good to read from you. My therapy seems to be going ok. I saw a specialist on complementary medicine this week who had all kinds of ideas what we could try but we decided we were going to wait for the first scans in May. Started to take vitamin D and K.

                                                What are you doing apart from your therapy like diet or alternative methods?

                                                How is your trial going?

                                                tcell
                                                Participant

                                                  Hi Brian,

                                                  good to read from you. My therapy seems to be going ok. I saw a specialist on complementary medicine this week who had all kinds of ideas what we could try but we decided we were going to wait for the first scans in May. Started to take vitamin D and K.

                                                  What are you doing apart from your therapy like diet or alternative methods?

                                                  How is your trial going?

                                                  pigs_sty
                                                  Participant
                                                    Hi Chris, what treatment did you end up going for if you don’t mind me asking. I can’t remeremember sorry, its good to hear from other people in england.
                                                    tcell
                                                    Participant

                                                      Hi,

                                                      I am currently on the GSK BRAF / MEK inhibitor for 10 weeks and doing fine so far. Latest bllod results came back ok.

                                                      Sorry fo the confusion but I am not in England but in Austria being treated at the Vienna University hospital by a specialized group.

                                                      Ho wis it going for you?

                                                      tcell
                                                      Participant

                                                        Hi,

                                                        I am currently on the GSK BRAF / MEK inhibitor for 10 weeks and doing fine so far. Latest bllod results came back ok.

                                                        Sorry fo the confusion but I am not in England but in Austria being treated at the Vienna University hospital by a specialized group.

                                                        Ho wis it going for you?

                                                        tcell
                                                        Participant

                                                          Hi,

                                                          I am currently on the GSK BRAF / MEK inhibitor for 10 weeks and doing fine so far. Latest bllod results came back ok.

                                                          Sorry fo the confusion but I am not in England but in Austria being treated at the Vienna University hospital by a specialized group.

                                                          Ho wis it going for you?

                                                          pigs_sty
                                                          Participant
                                                            Hi Chris, what treatment did you end up going for if you don’t mind me asking. I can’t remeremember sorry, its good to hear from other people in england.
                                                            pigs_sty
                                                            Participant
                                                              Hi Chris, what treatment did you end up going for if you don’t mind me asking. I can’t remeremember sorry, its good to hear from other people in england.
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