Could this be lung metastasis

As you know, melanoma is of the devil and can do most anything… However, “ground glass” appearance is a term often used by radiologists to describe pneumonitis – which is literally inflammation of the lungs. It is not a term used to categorize tumors. Pneumonitis and wheeze/dry cough are fairly common side effects of immunotherapy. Not sure if you experienced any of that when you were on therapy. I did and that is how my lungs were often described though I was post melanoma lung mets which were removed surgically before I started immunotherapy. Pneumonitis can be caused by many things – irritation from drugs, colds, flu, covid, pollution, asthma, etc. If there are no symptoms, then no treatment may be needed. If nagging cough or wheeze are present then inhalers like those used for asthma patients can be very helpful. If extreme, steroids and other drugs may be needed. Also, in the words of the Wizard, Dr. Weber, regarding immunotherapy – “This stuff is weird!” My last dose of immunotherapy was in June of 2013 and I still have occasional flares of the same joint pain I experienced then, flares of rashes, and pretty consistent dry mouth. So…all that to say, try not to worry too much and I think it is good that they are planning to do a follow up scan in 3 months.

For what it’s worth – celeste

It’s good news that your report didn’t mention melanoma, but it’s understandable that the presence of GGOs has you concerned. It’s important to keep in mind that GGOs can be caused by many different things, and not all of them are serious.

Since you mentioned that you are 5 years post ipi/nivi treatment and NED, it’s possible that the GGOs are related to the immunotherapy you received. It’s not uncommon for immunotherapy to cause inflammation in the lungs, which can appear as GGOs on a CT scan. However, it’s also possible that the GGOs are unrelated to your previous treatment.

The fact that your doctor has scheduled a repeat scan in 3 months suggests that they are monitoring the situation closely. This is a good sign, as it indicates that your doctor is taking a proactive approach to your care.

While waiting for your follow-up scan, it’s important to try to manage your worry as best you can. Focus on taking good care of yourself, both physically and emotionally. Make sure to get plenty of rest, eat a healthy diet, and stay active. Consider talking to a trusted friend or family member about your concerns, or seeking support from a mental health professional if you feel that would be helpful.

Remember that while waiting for test results can be difficult, worrying won’t change the outcome. Try to stay positive and take things one day at a time.