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Buttocks pain turns out to be tumor in spine
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Buttocks pain turns out to be tumor in spine

› Forums › General Melanoma Community › Buttocks pain turns out to be tumor in spine

  • Post
    • November 23, 2011 at 3:55 pm
    SStamps
    Participant
      My husband and I are sitting outside of Dallas waiting on Dr to call us back to tell us to go home or back to Houston for radiation or surgery. Mickey’s brain MRI was ok no new tumors and the ones left are shrinking ct of abdomen no new tumors and the ones left are shrinking. They added the spine MRI because of pain he is having. His 4th ipi was 9-23-11 pain started about one and half weeks later. How come ipi wouldn’t be working on spine tumor?
      Samantha

      My husband and I are sitting outside of Dallas waiting on Dr to call us back to tell us to go home or back to Houston for radiation or surgery. Mickey’s brain MRI was ok no new tumors and the ones left are shrinking ct of abdomen no new tumors and the ones left are shrinking. They added the spine MRI because of pain he is having. His 4th ipi was 9-23-11 pain started about one and half weeks later. How come ipi wouldn’t be working on spine tumor?
      Samantha

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    • Replies
        • November 24, 2011 at 1:04 am
        shellebrownies
        Participant

          If it is actually on the spinal cord (and not on the bone) then it could be because of the blood/brain barrier. I'm not sure how much study there has been on how well ipi is able to cross this. (Blood/brain barrier, which I believe also protects the spinal cord, has to do with medicines having a difficult time crossing through the protective barriers to treat those areas directly.)

          If the ipi is working on all of his other mets, then they might be able to treat the spinal met with something known to work well across the blood/brain barrier. (A chemo drug called Temodar comes to mind, but certainly there could be others…)

          If it's a tumor on the bone of the spine, then perhaps he is only a partial responder to the ipi and the treatment isn't working as well with the osseous disease. (That happened to my husband when he was on chemo…it shrank all of his mets except for the bone ones.)

          I wish you the best of luck with this; hopefully they will come up with a secondary treatment they can use to deal with it.

          Michelle, wife of Don

          • November 24, 2011 at 1:04 am
          shellebrownies
          Participant

            If it is actually on the spinal cord (and not on the bone) then it could be because of the blood/brain barrier. I'm not sure how much study there has been on how well ipi is able to cross this. (Blood/brain barrier, which I believe also protects the spinal cord, has to do with medicines having a difficult time crossing through the protective barriers to treat those areas directly.)

            If the ipi is working on all of his other mets, then they might be able to treat the spinal met with something known to work well across the blood/brain barrier. (A chemo drug called Temodar comes to mind, but certainly there could be others…)

            If it's a tumor on the bone of the spine, then perhaps he is only a partial responder to the ipi and the treatment isn't working as well with the osseous disease. (That happened to my husband when he was on chemo…it shrank all of his mets except for the bone ones.)

            I wish you the best of luck with this; hopefully they will come up with a secondary treatment they can use to deal with it.

            Michelle, wife of Don

            • November 24, 2011 at 1:04 am
            shellebrownies
            Participant

              If it is actually on the spinal cord (and not on the bone) then it could be because of the blood/brain barrier. I'm not sure how much study there has been on how well ipi is able to cross this. (Blood/brain barrier, which I believe also protects the spinal cord, has to do with medicines having a difficult time crossing through the protective barriers to treat those areas directly.)

              If the ipi is working on all of his other mets, then they might be able to treat the spinal met with something known to work well across the blood/brain barrier. (A chemo drug called Temodar comes to mind, but certainly there could be others…)

              If it's a tumor on the bone of the spine, then perhaps he is only a partial responder to the ipi and the treatment isn't working as well with the osseous disease. (That happened to my husband when he was on chemo…it shrank all of his mets except for the bone ones.)

              I wish you the best of luck with this; hopefully they will come up with a secondary treatment they can use to deal with it.

              Michelle, wife of Don

          Viewing 2 reply threads
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