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brain MRI and SRS
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brain MRI and SRS

› Forums › General Melanoma Community › brain MRI and SRS

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    • January 6, 2014 at 2:35 pm
    Pink
    Participant

      tomorriow going for another brain scan then Wed. meet with radiologist and neurp at Moffit. Initial MRI showed 3 small mets to brain. i am also going to start Ipi as soon as insurance approves it. if SRS does not work can they do it again  and does IPI cross the blood brain barrier.

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        • January 7, 2014 at 1:23 am
        Bubbles
        Participant

          Getting SRS is state of the art treatment for brain mets.  Especially when it is followed by ipi or an anti-PD1 product.  More and more studies are demonstrating the abscopal effect that occurs in the brain (and some studies are beginning to note that effect in the body as well) when radiation is followed by one of these drugs.  As to your question:  NO.  Ipi does not cross the blood brain barrier.  BUT…much more importantly, the cells (T-cells) that ipi triggers to fight melanoma DO!!!!!!!!!!!!!!!!  For more information about the latest and best treatments for melanoma brain mets from ASCO….you can check out my blog post on June 2.  Wishing you the very best.  Celeste

            • January 7, 2014 at 2:12 am
            Pink
            Participant

              Thanks for the info, I was looking at Pd1 but have to try Ipi first. My doctor says she is almost certain that it will be approved this year. I have Dr Kuchikar now but she is leaving so I may have Weber

              • January 7, 2014 at 3:40 am
              Bubbles
              Participant

                I was in an anti-PD1 trial with Dr. Weber at Moffit for 2 1/2 years.  I follow-up next with him in March.  He's a good guy and a brilliant MD.  Best of luck.  C

                • January 7, 2014 at 3:40 am
                Bubbles
                Participant

                  I was in an anti-PD1 trial with Dr. Weber at Moffit for 2 1/2 years.  I follow-up next with him in March.  He's a good guy and a brilliant MD.  Best of luck.  C

                  • January 7, 2014 at 3:40 am
                  Bubbles
                  Participant

                    I was in an anti-PD1 trial with Dr. Weber at Moffit for 2 1/2 years.  I follow-up next with him in March.  He's a good guy and a brilliant MD.  Best of luck.  C

                    • January 7, 2014 at 2:12 am
                    Pink
                    Participant

                      Thanks for the info, I was looking at Pd1 but have to try Ipi first. My doctor says she is almost certain that it will be approved this year. I have Dr Kuchikar now but she is leaving so I may have Weber

                      • January 7, 2014 at 2:12 am
                      Pink
                      Participant

                        Thanks for the info, I was looking at Pd1 but have to try Ipi first. My doctor says she is almost certain that it will be approved this year. I have Dr Kuchikar now but she is leaving so I may have Weber

                      • January 7, 2014 at 1:23 am
                      Bubbles
                      Participant

                        Getting SRS is state of the art treatment for brain mets.  Especially when it is followed by ipi or an anti-PD1 product.  More and more studies are demonstrating the abscopal effect that occurs in the brain (and some studies are beginning to note that effect in the body as well) when radiation is followed by one of these drugs.  As to your question:  NO.  Ipi does not cross the blood brain barrier.  BUT…much more importantly, the cells (T-cells) that ipi triggers to fight melanoma DO!!!!!!!!!!!!!!!!  For more information about the latest and best treatments for melanoma brain mets from ASCO….you can check out my blog post on June 2.  Wishing you the very best.  Celeste

                        • January 7, 2014 at 1:23 am
                        Bubbles
                        Participant

                          Getting SRS is state of the art treatment for brain mets.  Especially when it is followed by ipi or an anti-PD1 product.  More and more studies are demonstrating the abscopal effect that occurs in the brain (and some studies are beginning to note that effect in the body as well) when radiation is followed by one of these drugs.  As to your question:  NO.  Ipi does not cross the blood brain barrier.  BUT…much more importantly, the cells (T-cells) that ipi triggers to fight melanoma DO!!!!!!!!!!!!!!!!  For more information about the latest and best treatments for melanoma brain mets from ASCO….you can check out my blog post on June 2.  Wishing you the very best.  Celeste

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