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Brain mets have shrunk after Cyberknife radiation and Braf/Mek

Forums General Melanoma Community Brain mets have shrunk after Cyberknife radiation and Braf/Mek

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      Hi all,

      I thought I would share some good news…I had my first brain MRI two months after CyberKnife radiation and re-starting Braf/Mek in October. My brain mets have shrunk 1/3-1/4 and some of the smaller ones (I have 8) are barely detectable. The swelling of my brain has gone down and the mid-line shift caused by the mets has started to right itself. My radiation oncologist put me on “surveillance” with another brain MRI in March 2022. I go back next Wednesday for routine CT scans and see my medical oncologist; we’ll see what he wants to do next regarding medication.

      Definitely the best news I could have ever hoped for and an unexpected early Christmas gift! I will still continue Braf/Mek and possibly add immunotherapy once I get off Dex (currently on 1mg), but for a first follow-up, I’ll certainly take it!

      Wishing everyone a very Merry Christmas and best wishes for effective treatments and good news! Melanoma sucks but we are fighters!!

      Much love,


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          Well done Jenn. Great result.
            Great news Jen!!! Merry Christmas.
              Thank you both! CT scans of the rest of my body were all clear, so I am just continuing to fight these pesky brain mets!

              Many wishes for a happy New Year to everyone!

                Great news!!
                  Jen, wonderful news! Happy New Year to you.
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