› Forums › General Melanoma Community › BRAF/MEK Trial – Mental/Psych problems?
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- December 13, 2011 at 12:22 am
My father is 85, Stage IV and last year was able to do the Yervoy trial on a Compassionate Use grant. Due to the severe abdominal issues, and his being stuck in a wheelchair due to a spinal surgery, he had drop out after only two tretments. Luckily, it worked for a while, he was cancer-free for nearly a year. It came back and he has been on the BRAF/MEK trial for six weeks or so. Lately his mental status took a dive, wasn't even able to sleep, very agitated and completely confused/wacked out. They thought it might be a calcium issue but now they feel
My father is 85, Stage IV and last year was able to do the Yervoy trial on a Compassionate Use grant. Due to the severe abdominal issues, and his being stuck in a wheelchair due to a spinal surgery, he had drop out after only two tretments. Luckily, it worked for a while, he was cancer-free for nearly a year. It came back and he has been on the BRAF/MEK trial for six weeks or so. Lately his mental status took a dive, wasn't even able to sleep, very agitated and completely confused/wacked out. They thought it might be a calcium issue but now they feel it is low phosphorus and he is going to have to stop the BRAF/MEK treatment. Has anyone heard or had any experience with a dementia from the medication? I'm hoping the treatments he was able to have may work, as before, for at least a number of months if not longer. But I am curious to see if anyone else had similar experience or symptoms. Also interested to hear if anyone stopped treatment early and still had any positive outcome. Good luck to you all and thanks for any light anyone might be able to shine on this for me.
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