Auto immune disease and immuno therapy
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Auto immune disease and immuno therapy

› Forums › General Melanoma Community › Auto immune disease and immuno therapy

  • Post
    • October 29, 2016 at 3:37 pm
    SOLE
    Participant

    Can the former prevent the latter?

Viewing 8 reply threads
  • Replies
      • October 29, 2016 at 5:07 pm
      cancersnewnormal
      Participant
      • October 29, 2016 at 5:07 pm
      cancersnewnormal
      Participant
        • October 29, 2016 at 5:17 pm
        jpg
        Participant

        In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

        • October 29, 2016 at 5:17 pm
        jpg
        Participant

        In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

        • October 29, 2016 at 5:44 pm
        cancersnewnormal
        Participant

        That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

        • October 29, 2016 at 5:44 pm
        cancersnewnormal
        Participant

        That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

        • October 29, 2016 at 5:44 pm
        cancersnewnormal
        Participant

        That is quite true. More and more immunotherapy patients are cropping up with autoimmune issues. My joints are currently screaming at me. From what I understand, patients with pre-existing autoimmune disease are not accepted into most of the current immunotherapy trials, however it does not exclude them from receiving currently approved drugs. That said, I would strongly recommend an oncologist specializing in melanoma if you are a patient with autoimmune issues.

        • October 29, 2016 at 5:17 pm
        jpg
        Participant

        In fact it can cause the other,  immunotherapy can cause auto immune disease or make it worse.  there is a good discussion of it on http://www.melanomaforum.org, look for MarySue's posts.

      • October 29, 2016 at 5:07 pm
      cancersnewnormal
      Participant
      • October 29, 2016 at 6:30 pm
      Bubbles
      Participant

      Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

      However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

      c

      • October 29, 2016 at 6:30 pm
      Bubbles
      Participant

      Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

      However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

      c

      • October 29, 2016 at 6:30 pm
      Bubbles
      Participant

      Since we know that immunotherapy, of all sorts, can actually produce serious immune related side effects….for a long time folks with pre-existing immunologic disease were not allowed participation in trials, or were withheld from treatment, with those therapies.  Prior immune related disease is still a very important aspect to consider and should be carefully evaluated with an oncologist….ie not taken lightly….when considering immunotherapy as a treatment for melanoma.

      However, we are learning that some patients with a pre-existing immuological disease process can achieve success with immunotherapy.

      http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2016/04/anti-pd1-success-in-melanoma-despite.html

      c

      • October 29, 2016 at 6:56 pm
      SOLE
      Participant

      Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

      • October 29, 2016 at 6:56 pm
      SOLE
      Participant

      Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

      • October 29, 2016 at 6:56 pm
      SOLE
      Participant

      Thank you for your answers. I ask because I have to find out about my agglutinate platelet condition that lowers my apparent count to 40,000-60,000. My oncologist was maybe thinking of a immune disease called ITP (i think…). I will be investigating this in the coming weeks. Needless to say, it is another source of stress knowing that cancer cells already aggreagate the platelets to form tumours

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