Anybody on E7080, especially in Australia?
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Anybody on E7080, especially in Australia?

› Forums › General Melanoma Community › Anybody on E7080, especially in Australia?

  • Post
    • October 1, 2012 at 2:15 pm
    SharonAust
    Participant

    Hello from Sydney Australia,

    My friend has Stage IV unresectable melanoma (still confined to lymph). She has been on vemurafenib (Zelboraf) and had an unusually bad experience with side effects. She's been offered a place on trial of E7080, but is nervous to go on another clinical trial.

    Any info on side effects from E7080, especially compared to Zelboraf?

    Hello from Sydney Australia,

    My friend has Stage IV unresectable melanoma (still confined to lymph). She has been on vemurafenib (Zelboraf) and had an unusually bad experience with side effects. She's been offered a place on trial of E7080, but is nervous to go on another clinical trial.

    Any info on side effects from E7080, especially compared to Zelboraf?

Viewing 5 reply threads
  • Replies
      • October 2, 2012 at 12:33 pm
      FormerCaregiver
      Participant

      Unfortunately, the big problem locally is that there is a serious lack stage IV
      treatment options. New clinical trials seem to be very limited in number, so it is good
      that your friend has the chance to try E7080. For more info see:
      http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

      Hope this helps

      Frank from Australia

        • October 3, 2012 at 12:27 pm
        SharonAust
        Participant

        Hi Frank,

        Thanks for the info, much appreciated and best regards,

        Sharon

        • October 3, 2012 at 12:27 pm
        SharonAust
        Participant

        Hi Frank,

        Thanks for the info, much appreciated and best regards,

        Sharon

        • October 3, 2012 at 12:27 pm
        SharonAust
        Participant

        Hi Frank,

        Thanks for the info, much appreciated and best regards,

        Sharon

      • October 2, 2012 at 12:33 pm
      FormerCaregiver
      Participant

      Unfortunately, the big problem locally is that there is a serious lack stage IV
      treatment options. New clinical trials seem to be very limited in number, so it is good
      that your friend has the chance to try E7080. For more info see:
      http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

      Hope this helps

      Frank from Australia

      • October 2, 2012 at 12:33 pm
      FormerCaregiver
      Participant

      Unfortunately, the big problem locally is that there is a serious lack stage IV
      treatment options. New clinical trials seem to be very limited in number, so it is good
      that your friend has the chance to try E7080. For more info see:
      http://www.nature.com/bjc/journal/v106/n10/full/bjc2012154a.html

      Hope this helps

      Frank from Australia

      • October 2, 2012 at 2:34 pm
      Lisa – Aust
      Participant

      Hi Sharon,

      I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

      I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

      Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

      Good luck

      Lisa

        • October 3, 2012 at 12:29 pm
        SharonAust
        Participant

        Dear Lisa,

        Thanks so much for the information and good wishes, much appreciated

        Sharon

        • October 3, 2012 at 12:29 pm
        SharonAust
        Participant

        Dear Lisa,

        Thanks so much for the information and good wishes, much appreciated

        Sharon

        • October 3, 2012 at 12:29 pm
        SharonAust
        Participant

        Dear Lisa,

        Thanks so much for the information and good wishes, much appreciated

        Sharon

      • October 2, 2012 at 2:34 pm
      Lisa – Aust
      Participant

      Hi Sharon,

      I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

      I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

      Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

      Good luck

      Lisa

      • October 2, 2012 at 2:34 pm
      Lisa – Aust
      Participant

      Hi Sharon,

      I am over in Perth and I know a few of the people who have stopped responding to the Braf inhibitor (GSK) have been offered the E7080 trial as the next option. A friend of ours, who was quite sick and has since passed, didnt have any major side effects at all. She actually stabilised on the drug (maybe some slight progression), but she was then taken off and given ipi, which she didnt have any luck with either, unfortunately. Another lady is still on the trial, but I havent seen her since she started, so unsure about her side effects.

      I think I vaguely recall someone on the board having some luck with it, but I may be wrong.

      Sorry to hear your friend had a hard time with Braf, and I hope she has some success with her next treatment.

      Good luck

      Lisa

Viewing 5 reply threads
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