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Anti-PD1 trials

Forums General Melanoma Community Anti-PD1 trials

  • Post
    dian in spokane
    Participant

      can anyone tell me where they are doing anti pd1 trials? I'm willing to travel some, but I'd prefer something on the western side of the US.

       

      thanks,

       

      dian in spokane

      can anyone tell me where they are doing anti pd1 trials? I'm willing to travel some, but I'd prefer something on the western side of the US.

       

      thanks,

       

      dian in spokane

    Viewing 8 reply threads
    • Replies
        killmel
        Participant

          Hi Dian,

           

          There are many pd1 trials around the USA. Depending upon what is going on with you then you might qualify for a trial:

          Do you have measurable disease is a basic criteria  : 1 CM or more.

          Past treatment is also consideration: usually you have to wait 4 weeks  since your last treatment

          PD1 trials have been requiring a  fresh biopsy- can you provide a biopsy, fresh if needed.

          I suggest that you look for trials that you meet the criteria & then worry about the location.

          Good Luck

          killmel
          Participant

            Hi Dian,

             

            There are many pd1 trials around the USA. Depending upon what is going on with you then you might qualify for a trial:

            Do you have measurable disease is a basic criteria  : 1 CM or more.

            Past treatment is also consideration: usually you have to wait 4 weeks  since your last treatment

            PD1 trials have been requiring a  fresh biopsy- can you provide a biopsy, fresh if needed.

            I suggest that you look for trials that you meet the criteria & then worry about the location.

            Good Luck

            killmel
            Participant

              Hi Dian,

               

              There are many pd1 trials around the USA. Depending upon what is going on with you then you might qualify for a trial:

              Do you have measurable disease is a basic criteria  : 1 CM or more.

              Past treatment is also consideration: usually you have to wait 4 weeks  since your last treatment

              PD1 trials have been requiring a  fresh biopsy- can you provide a biopsy, fresh if needed.

              I suggest that you look for trials that you meet the criteria & then worry about the location.

              Good Luck

                dian in spokane
                Participant

                  thanks anonymous!

                  I was frustrated in my search but actually found the trial I was looking for and have been talking to the trial nurse. But for a short time, I thought there was NO anti pd 1 trial at SCCA (in seattle) so I was kind of hoping I'd see a little feedback on some other western clinics, so I could continue my search.  I've moved on.

                   

                  But.. I remember 8 yrs ago on this board, a query like that would have gotten a half a dozen responses in a 24 hour period.

                  thanks for piping up!

                   

                  Dian

                  dian in spokane
                  Participant

                    thanks anonymous!

                    I was frustrated in my search but actually found the trial I was looking for and have been talking to the trial nurse. But for a short time, I thought there was NO anti pd 1 trial at SCCA (in seattle) so I was kind of hoping I'd see a little feedback on some other western clinics, so I could continue my search.  I've moved on.

                     

                    But.. I remember 8 yrs ago on this board, a query like that would have gotten a half a dozen responses in a 24 hour period.

                    thanks for piping up!

                     

                    Dian

                    dian in spokane
                    Participant

                      thanks anonymous!

                      I was frustrated in my search but actually found the trial I was looking for and have been talking to the trial nurse. But for a short time, I thought there was NO anti pd 1 trial at SCCA (in seattle) so I was kind of hoping I'd see a little feedback on some other western clinics, so I could continue my search.  I've moved on.

                       

                      But.. I remember 8 yrs ago on this board, a query like that would have gotten a half a dozen responses in a 24 hour period.

                      thanks for piping up!

                       

                      Dian

                    killmel
                    Participant

                      Dian,

                       

                      Did you complete your radiation??? What was your response to radiation..any shrinkage?? What is the size of your tumor in your lungs now???

                       

                      A

                        dian in spokane
                        Participant

                          gosh, I guess I forgot to actually post my results.

                           

                          The SRS worked well on the small tumor I had in my lung, but a couple more spots are now involved. A second tumor in my right lung has arrived, and a long, slow changing spot in my lower left lobe that could be a tumor or a lymph node.

                           

                          So it's looking like time for systemic treatment.

                          I am kind of leaning toward IL 2. guess I will post abut that sometime today.

                           

                          So..the old tumor gone, just a nasty radiation footprint on my lung. New  tumor, 1.4 I forgot to take a copy of my report home, so I forget the SUV.. not that high yet, but.. zero to 4. something between scans.

                          dian in spokane
                          Participant

                            gosh, I guess I forgot to actually post my results.

                             

                            The SRS worked well on the small tumor I had in my lung, but a couple more spots are now involved. A second tumor in my right lung has arrived, and a long, slow changing spot in my lower left lobe that could be a tumor or a lymph node.

                             

                            So it's looking like time for systemic treatment.

                            I am kind of leaning toward IL 2. guess I will post abut that sometime today.

                             

                            So..the old tumor gone, just a nasty radiation footprint on my lung. New  tumor, 1.4 I forgot to take a copy of my report home, so I forget the SUV.. not that high yet, but.. zero to 4. something between scans.

                            dian in spokane
                            Participant

                              gosh, I guess I forgot to actually post my results.

                               

                              The SRS worked well on the small tumor I had in my lung, but a couple more spots are now involved. A second tumor in my right lung has arrived, and a long, slow changing spot in my lower left lobe that could be a tumor or a lymph node.

                               

                              So it's looking like time for systemic treatment.

                              I am kind of leaning toward IL 2. guess I will post abut that sometime today.

                               

                              So..the old tumor gone, just a nasty radiation footprint on my lung. New  tumor, 1.4 I forgot to take a copy of my report home, so I forget the SUV.. not that high yet, but.. zero to 4. something between scans.

                              killmel
                              Participant

                                Here are IL melanoma  trials at SCCA.  It is my understanding that you can have IL2 treatment & you do NOT have to be in a trial. IL2 is a FDA approved treatment, as well as, Yervoy/Ipilimumab. It might be better for you to not have to deal with clinical trial protocol & all the rules of the clinical trial.Plus your doctor has more freedom to treat you.

                                 

                                IL-2 "SELECT" for Advanced Melanoma
                                The High-Dose Aldesleukin (IL-2) "SELECT" Trial: A Prospective Tissue Collection Protocol to Investigate Predictive Models of Response to High-Dose IL-2 Treatments in Patients With Advance Melanoma
                                 
                                L-21/Ipilimumab Combination for Melanoma

                                A Phase I Dose Escalation Study of BMS-982470 (Recombinant Interleukin 21, rIL-21) in Combination With Ipilimumab in Subjects With Unresectable Stage III or Stage IV Melanoma
                                killmel
                                Participant

                                  Here are IL melanoma  trials at SCCA.  It is my understanding that you can have IL2 treatment & you do NOT have to be in a trial. IL2 is a FDA approved treatment, as well as, Yervoy/Ipilimumab. It might be better for you to not have to deal with clinical trial protocol & all the rules of the clinical trial.Plus your doctor has more freedom to treat you.

                                   

                                  IL-2 "SELECT" for Advanced Melanoma
                                  The High-Dose Aldesleukin (IL-2) "SELECT" Trial: A Prospective Tissue Collection Protocol to Investigate Predictive Models of Response to High-Dose IL-2 Treatments in Patients With Advance Melanoma
                                   
                                  L-21/Ipilimumab Combination for Melanoma

                                  A Phase I Dose Escalation Study of BMS-982470 (Recombinant Interleukin 21, rIL-21) in Combination With Ipilimumab in Subjects With Unresectable Stage III or Stage IV Melanoma
                                  Cooper
                                  Participant

                                    Check over at http://www.melanomaforum.org   they have lists of the PD1 trials or you can email for a specific location

                                    Cooper
                                    Participant

                                      Check over at http://www.melanomaforum.org   they have lists of the PD1 trials or you can email for a specific location

                                      Cooper
                                      Participant

                                        Check over at http://www.melanomaforum.org   they have lists of the PD1 trials or you can email for a specific location

                                        killmel
                                        Participant

                                          Here are IL melanoma  trials at SCCA.  It is my understanding that you can have IL2 treatment & you do NOT have to be in a trial. IL2 is a FDA approved treatment, as well as, Yervoy/Ipilimumab. It might be better for you to not have to deal with clinical trial protocol & all the rules of the clinical trial.Plus your doctor has more freedom to treat you.

                                           

                                          IL-2 "SELECT" for Advanced Melanoma
                                          The High-Dose Aldesleukin (IL-2) "SELECT" Trial: A Prospective Tissue Collection Protocol to Investigate Predictive Models of Response to High-Dose IL-2 Treatments in Patients With Advance Melanoma
                                           
                                          L-21/Ipilimumab Combination for Melanoma

                                          A Phase I Dose Escalation Study of BMS-982470 (Recombinant Interleukin 21, rIL-21) in Combination With Ipilimumab in Subjects With Unresectable Stage III or Stage IV Melanoma
                                        killmel
                                        Participant

                                          Dian,

                                           

                                          Did you complete your radiation??? What was your response to radiation..any shrinkage?? What is the size of your tumor in your lungs now???

                                           

                                          A

                                          killmel
                                          Participant

                                            Dian,

                                             

                                            Did you complete your radiation??? What was your response to radiation..any shrinkage?? What is the size of your tumor in your lungs now???

                                             

                                            A

                                            Napa K
                                            Participant

                                              Hi Diane-

                                              Regarding anti-PD1, have you tried contacting Angeles Clinic, Los Angeles (Dr. Hamid) or California Pacific Medical Clinic in San Francisco (Dr. Minor)? I have heard of multiple people getting on trial recently at these sites.

                                              Napa K
                                              Participant

                                                Hi Diane-

                                                Regarding anti-PD1, have you tried contacting Angeles Clinic, Los Angeles (Dr. Hamid) or California Pacific Medical Clinic in San Francisco (Dr. Minor)? I have heard of multiple people getting on trial recently at these sites.

                                                Napa K
                                                Participant

                                                  Hi Diane-

                                                  Regarding anti-PD1, have you tried contacting Angeles Clinic, Los Angeles (Dr. Hamid) or California Pacific Medical Clinic in San Francisco (Dr. Minor)? I have heard of multiple people getting on trial recently at these sites.

                                              Viewing 8 reply threads
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