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Anti-PD1 after Ipi
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Anti-PD1 after Ipi

› Forums › General Melanoma Community › Anti-PD1 after Ipi

  • Post
    • February 7, 2014 at 1:47 pm
    POW
    Participant

      I have read a couple of anecdotal reports of patients who failed ipi then getting anti-PD1 and having success– even shrinking bone mets. I know that there was a clinical trial a year or so ago specifically designed to see the effect of anti-PD1 in patients who had failed or progressed on ipi. Any one know how it worked out?

    Viewing 8 reply threads
    • Replies
        • February 7, 2014 at 4:19 pm
        JerryfromFauq
        Participant

          Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

           

            • February 8, 2014 at 6:04 pm
            Pink
            Participant

              I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

              • February 8, 2014 at 6:04 pm
              Pink
              Participant

                I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

                • February 8, 2014 at 6:04 pm
                Pink
                Participant

                  I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

                  • February 15, 2014 at 5:39 pm
                  Michelem
                  Participant

                    My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

                    • February 15, 2014 at 5:39 pm
                    Michelem
                    Participant

                      My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

                      • February 15, 2014 at 5:39 pm
                      Michelem
                      Participant

                        My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

                      • February 7, 2014 at 4:19 pm
                      JerryfromFauq
                      Participant

                        Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

                         

                        • February 7, 2014 at 4:19 pm
                        JerryfromFauq
                        Participant

                          Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

                           

                          • February 11, 2014 at 3:46 am
                          Hstevens0072
                          Participant

                            I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

                            • February 11, 2014 at 3:46 am
                            Hstevens0072
                            Participant

                              I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

                              • February 11, 2014 at 3:46 am
                              Hstevens0072
                              Participant

                                I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

                                • February 12, 2014 at 6:35 am
                                benp
                                Participant

                                  You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

                                  • February 12, 2014 at 6:35 am
                                  benp
                                  Participant

                                    You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

                                    • February 12, 2014 at 6:35 am
                                    benp
                                    Participant

                                      You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

                                  Viewing 8 reply threads
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