Anti-PD1 after Ipi
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Anti-PD1 after Ipi

› Forums › General Melanoma Community › Anti-PD1 after Ipi

  • Post
    • February 7, 2014 at 1:47 pm
    POW
    Participant

    I have read a couple of anecdotal reports of patients who failed ipi then getting anti-PD1 and having success– even shrinking bone mets. I know that there was a clinical trial a year or so ago specifically designed to see the effect of anti-PD1 in patients who had failed or progressed on ipi. Any one know how it worked out?

Viewing 8 reply threads
  • Replies
      • February 7, 2014 at 4:19 pm
      JerryfromFauq
      Participant

      Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

       

        • February 8, 2014 at 6:04 pm
        Pink
        Participant

        I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

        • February 8, 2014 at 6:04 pm
        Pink
        Participant

        I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

        • February 8, 2014 at 6:04 pm
        Pink
        Participant

        I am having treatment at Moffitt with SRS for small brain mets and Ipi for the systemic ones. They have mentioned PD1 if this did not work so I would say the trial is still going on.

        • February 15, 2014 at 5:39 pm
        Michelem
        Participant

        My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

        • February 15, 2014 at 5:39 pm
        Michelem
        Participant

        My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

        • February 15, 2014 at 5:39 pm
        Michelem
        Participant

        My husband started ipi this week. We were told that the PD-1 trial is very promising but that it is closed. I saw another thread here on that topic – a person who was very much hoping for PD-1 but could not get into the trial.  Are these trials totally centralized? Or could it be that the SF trial is closed but PD-1 trials elsewhere are open?

      • February 7, 2014 at 4:19 pm
      JerryfromFauq
      Participant

      Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

       

      • February 7, 2014 at 4:19 pm
      JerryfromFauq
      Participant

      Last I heard it is still underway.  I know that as of last month Dr Weber was still taking people in on it.

       

      • February 11, 2014 at 3:46 am
      Hstevens0072
      Participant

      I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

      • February 11, 2014 at 3:46 am
      Hstevens0072
      Participant

      I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

      • February 11, 2014 at 3:46 am
      Hstevens0072
      Participant

      I progressed on Ipi then started MK3475 last June – all tumors except one are gone and the one remaing is 82% smaller.  No side effects except for a non-itchy rash 🙂

      • February 12, 2014 at 6:35 am
      benp
      Participant

      You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

      • February 12, 2014 at 6:35 am
      benp
      Participant

      You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

      • February 12, 2014 at 6:35 am
      benp
      Participant

      You can add my anecdotal report to the list – I failed Ipi, just had my week 39 infusion of MK-3475, all looking pretty good. I had initial regression, and now stable disease.

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