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Abraxane and Avastin

Forums General Melanoma Community Abraxane and Avastin

  • Post
    cheryl brodersen
    Participant

    My husband, Steve,  has had 3 treatments, a week break, and starts the next three treatments next week…and then the scan.

    Anyone have any experiences with this combo? He has been pretty sick, but his doctor said that is to be expected after the 18 rounds of DTIC he went through last year (in 14 months). He was certainly never this ill and unable to do anything. The Neulasta seems to have kicked in and he's back to being up and around.

    I would love to hear anything about the A/A treatment, good or bad.

    Thanks,

    Cheryl, wife of Steve, Stg. IV

    My husband, Steve,  has had 3 treatments, a week break, and starts the next three treatments next week…and then the scan.

    Anyone have any experiences with this combo? He has been pretty sick, but his doctor said that is to be expected after the 18 rounds of DTIC he went through last year (in 14 months). He was certainly never this ill and unable to do anything. The Neulasta seems to have kicked in and he's back to being up and around.

    I would love to hear anything about the A/A treatment, good or bad.

    Thanks,

    Cheryl, wife of Steve, Stg. IV

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  • Replies
      AndyD
      Participant

      He Cheryl, I just found your post today. I'm on a similar treatment (Avastin and Taxotere). Taxotere is also called docetaxel which sounds like it might be a similar family of drugs to your abraxane which is also called paclitaxel. I've only had 1 treatment so far and haven't been too sick yet. I expect to lose my hair next week. I'm already tired and weak from previous ipi and cancer progression so I might not be feeling the full effects.

      From what I've found with google research, it seems like the combos have maybe a 50% chance at tumor reduction, then a small chance at progression free survival.

      Hope to hear if your hub is responding.

       

      Andy, stage IV

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      AndyD
      Participant

      He Cheryl, I just found your post today. I'm on a similar treatment (Avastin and Taxotere). Taxotere is also called docetaxel which sounds like it might be a similar family of drugs to your abraxane which is also called paclitaxel. I've only had 1 treatment so far and haven't been too sick yet. I expect to lose my hair next week. I'm already tired and weak from previous ipi and cancer progression so I might not be feeling the full effects.

      From what I've found with google research, it seems like the combos have maybe a 50% chance at tumor reduction, then a small chance at progression free survival.

      Hope to hear if your hub is responding.

       

      Andy, stage IV

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      deirgey
      Participant

      hi Cheryl,

        My father is taking the A/A combo as well.  He started about 4 to 5 weeks ago.  He has had a nausea and is pretty tired.  He will get another scan in 3 weeks.  Seems like they started their treatments about the same time.  My father is with Arizona Cancer Center as well but with a different doctor.  Keep us updated on your husbands progress and I will do the same.  Will be thinking of your family in these next few weeks.

       

      Deidre Grief, father stage IV

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      deirgey
      Participant

      hi Cheryl,

        My father is taking the A/A combo as well.  He started about 4 to 5 weeks ago.  He has had a nausea and is pretty tired.  He will get another scan in 3 weeks.  Seems like they started their treatments about the same time.  My father is with Arizona Cancer Center as well but with a different doctor.  Keep us updated on your husbands progress and I will do the same.  Will be thinking of your family in these next few weeks.

       

      Deidre Grief, father stage IV

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      hope4cure1
      Participant

      My husband just had his 5th treatment of avastin/abraxane/carboplatin.  He gets tired maybe the 3rd day after each treatment, but has rebounded fairly quickly each time.  He had a week off after treatment 4, and that helped.  He lost his hair week 3.  He also started getting the metallic taste about the same time.  The first night each time, he has said he has indigestion.  He snow skiied the weekend right before treatment, and was able to ski all day 2 days in a row.  During his week off of treatment, he went skiing, and felt a lot more out of breath.  He did manage to ski half a day.  We are going skiing again this weekend, and next, so it will be interesting to see what his strength will be now. His doctor did say that he is tolerating treatment uncommonly well.   Of course, the real question is if this treatment is helping.  I will keep you all in my prayers, and will be anxious to hear good news from everyone!

      Another Cheryl :)

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      hope4cure1
      Participant

      My husband just had his 5th treatment of avastin/abraxane/carboplatin.  He gets tired maybe the 3rd day after each treatment, but has rebounded fairly quickly each time.  He had a week off after treatment 4, and that helped.  He lost his hair week 3.  He also started getting the metallic taste about the same time.  The first night each time, he has said he has indigestion.  He snow skiied the weekend right before treatment, and was able to ski all day 2 days in a row.  During his week off of treatment, he went skiing, and felt a lot more out of breath.  He did manage to ski half a day.  We are going skiing again this weekend, and next, so it will be interesting to see what his strength will be now. His doctor did say that he is tolerating treatment uncommonly well.   Of course, the real question is if this treatment is helping.  I will keep you all in my prayers, and will be anxious to hear good news from everyone!

      Another Cheryl :)

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      EuniceB
      Participant

      Wednesday a board of cancer specialists recommended the narcotic Avastin shouldn't be authorized by the FDA for the treatment of cancer. The drug is ineffective and has serious side effects, the panel determined. The Food and Drug Administration will make a last decision in July. The proof is here: A panel recommends disapproving breast cancer drug

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      EuniceB
      Participant

      Wednesday a board of cancer specialists recommended the narcotic Avastin shouldn't be authorized by the FDA for the treatment of cancer. The drug is ineffective and has serious side effects, the panel determined. The Food and Drug Administration will make a last decision in July. The proof is here: A panel recommends disapproving breast cancer drug

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      shellebrownies
      Participant

      My husband is 1/2 through his 2nd round of carboplatin/abraxane. He has had a great response from the combo, but has had some delayed nausea/vomiting about 4 days after  that took 4 days to resolve. Now he feels great.

      Best of luck to Steve. I hope his side effects get better soon!

      Michelle, wife of Don

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      shellebrownies
      Participant

      My husband is 1/2 through his 2nd round of carboplatin/abraxane. He has had a great response from the combo, but has had some delayed nausea/vomiting about 4 days after  that took 4 days to resolve. Now he feels great.

      Best of luck to Steve. I hope his side effects get better soon!

      Michelle, wife of Don

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