The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Abraxane and Avastin

Forums General Melanoma Community Abraxane and Avastin

  • Post
    cheryl brodersen
    Participant

      My husband, Steve,  has had 3 treatments, a week break, and starts the next three treatments next week…and then the scan.

      Anyone have any experiences with this combo? He has been pretty sick, but his doctor said that is to be expected after the 18 rounds of DTIC he went through last year (in 14 months). He was certainly never this ill and unable to do anything. The Neulasta seems to have kicked in and he's back to being up and around.

      I would love to hear anything about the A/A treatment, good or bad.

      Thanks,

      Cheryl, wife of Steve, Stg. IV

      My husband, Steve,  has had 3 treatments, a week break, and starts the next three treatments next week…and then the scan.

      Anyone have any experiences with this combo? He has been pretty sick, but his doctor said that is to be expected after the 18 rounds of DTIC he went through last year (in 14 months). He was certainly never this ill and unable to do anything. The Neulasta seems to have kicked in and he's back to being up and around.

      I would love to hear anything about the A/A treatment, good or bad.

      Thanks,

      Cheryl, wife of Steve, Stg. IV

    Viewing 9 reply threads
    • Replies
        AndyD
        Participant

          He Cheryl, I just found your post today. I'm on a similar treatment (Avastin and Taxotere). Taxotere is also called docetaxel which sounds like it might be a similar family of drugs to your abraxane which is also called paclitaxel. I've only had 1 treatment so far and haven't been too sick yet. I expect to lose my hair next week. I'm already tired and weak from previous ipi and cancer progression so I might not be feeling the full effects.

          From what I've found with google research, it seems like the combos have maybe a 50% chance at tumor reduction, then a small chance at progression free survival.

          Hope to hear if your hub is responding.

           

          Andy, stage IV

          AndyD
          Participant

            He Cheryl, I just found your post today. I'm on a similar treatment (Avastin and Taxotere). Taxotere is also called docetaxel which sounds like it might be a similar family of drugs to your abraxane which is also called paclitaxel. I've only had 1 treatment so far and haven't been too sick yet. I expect to lose my hair next week. I'm already tired and weak from previous ipi and cancer progression so I might not be feeling the full effects.

            From what I've found with google research, it seems like the combos have maybe a 50% chance at tumor reduction, then a small chance at progression free survival.

            Hope to hear if your hub is responding.

             

            Andy, stage IV

            deirgey
            Participant

              hi Cheryl,

                My father is taking the A/A combo as well.  He started about 4 to 5 weeks ago.  He has had a nausea and is pretty tired.  He will get another scan in 3 weeks.  Seems like they started their treatments about the same time.  My father is with Arizona Cancer Center as well but with a different doctor.  Keep us updated on your husbands progress and I will do the same.  Will be thinking of your family in these next few weeks.

               

              Deidre Grief, father stage IV

              deirgey
              Participant

                hi Cheryl,

                  My father is taking the A/A combo as well.  He started about 4 to 5 weeks ago.  He has had a nausea and is pretty tired.  He will get another scan in 3 weeks.  Seems like they started their treatments about the same time.  My father is with Arizona Cancer Center as well but with a different doctor.  Keep us updated on your husbands progress and I will do the same.  Will be thinking of your family in these next few weeks.

                 

                Deidre Grief, father stage IV

                hope4cure1
                Participant

                  My husband just had his 5th treatment of avastin/abraxane/carboplatin.  He gets tired maybe the 3rd day after each treatment, but has rebounded fairly quickly each time.  He had a week off after treatment 4, and that helped.  He lost his hair week 3.  He also started getting the metallic taste about the same time.  The first night each time, he has said he has indigestion.  He snow skiied the weekend right before treatment, and was able to ski all day 2 days in a row.  During his week off of treatment, he went skiing, and felt a lot more out of breath.  He did manage to ski half a day.  We are going skiing again this weekend, and next, so it will be interesting to see what his strength will be now. His doctor did say that he is tolerating treatment uncommonly well.   Of course, the real question is if this treatment is helping.  I will keep you all in my prayers, and will be anxious to hear good news from everyone!

                  Another Cheryl 🙂

                  hope4cure1
                  Participant

                    My husband just had his 5th treatment of avastin/abraxane/carboplatin.  He gets tired maybe the 3rd day after each treatment, but has rebounded fairly quickly each time.  He had a week off after treatment 4, and that helped.  He lost his hair week 3.  He also started getting the metallic taste about the same time.  The first night each time, he has said he has indigestion.  He snow skiied the weekend right before treatment, and was able to ski all day 2 days in a row.  During his week off of treatment, he went skiing, and felt a lot more out of breath.  He did manage to ski half a day.  We are going skiing again this weekend, and next, so it will be interesting to see what his strength will be now. His doctor did say that he is tolerating treatment uncommonly well.   Of course, the real question is if this treatment is helping.  I will keep you all in my prayers, and will be anxious to hear good news from everyone!

                    Another Cheryl 🙂

                    EuniceB
                    Participant

                      Wednesday a board of cancer specialists recommended the narcotic Avastin shouldn't be authorized by the FDA for the treatment of cancer. The drug is ineffective and has serious side effects, the panel determined. The Food and Drug Administration will make a last decision in July. The proof is here: A panel recommends disapproving breast cancer drug

                      EuniceB
                      Participant

                        Wednesday a board of cancer specialists recommended the narcotic Avastin shouldn't be authorized by the FDA for the treatment of cancer. The drug is ineffective and has serious side effects, the panel determined. The Food and Drug Administration will make a last decision in July. The proof is here: A panel recommends disapproving breast cancer drug

                        shellebrownies
                        Participant

                          My husband is 1/2 through his 2nd round of carboplatin/abraxane. He has had a great response from the combo, but has had some delayed nausea/vomiting about 4 days after  that took 4 days to resolve. Now he feels great.

                          Best of luck to Steve. I hope his side effects get better soon!

                          Michelle, wife of Don

                          shellebrownies
                          Participant

                            My husband is 1/2 through his 2nd round of carboplatin/abraxane. He has had a great response from the combo, but has had some delayed nausea/vomiting about 4 days after  that took 4 days to resolve. Now he feels great.

                            Best of luck to Steve. I hope his side effects get better soon!

                            Michelle, wife of Don

                        Viewing 9 reply threads
                        • You must be logged in to reply to this topic.
                        About the MRF Patient Forum

                        The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                        The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.