Mitosis
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Mitosis

› Forums › General Melanoma Community › Mitosis

  • Post
    • November 1, 2013 at 1:21 pm
    SBeattie
    Participant

    just curious if any of you smart, wonderful folk know if one is 'locked in' with mitotic rate of initial lesion…can it slow down, or speed up in subsequent lesions/metastasis? Haven't seen anything in the lit/research I've perused over the last 2  + yrs…however, I know it is a prognostic indicator of recurrence…thanks very much

Viewing 5 reply threads
  • Replies
      • November 1, 2013 at 2:11 pm
      sharon0803
      Participant

      Great question!  I too wondered about this.

       

        • November 1, 2013 at 2:57 pm
        DebbieH
        Participant

        I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

        DebbieH, stage 3C, NED 12+ years after interferon and no scans

        • November 1, 2013 at 3:08 pm
        SBeattie
        Participant

        thank you…!

        • November 1, 2013 at 3:08 pm
        SBeattie
        Participant

        thank you…!

        • November 1, 2013 at 3:08 pm
        SBeattie
        Participant

        thank you…!

        • November 1, 2013 at 2:57 pm
        DebbieH
        Participant

        I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

        DebbieH, stage 3C, NED 12+ years after interferon and no scans

        • November 1, 2013 at 2:57 pm
        DebbieH
        Participant

        I wouldn't worry too much about it.  I've seen people with high mitotic rates with no recurrence and I've seen others with very low ones (like mine at less than 1) come back. 

        DebbieH, stage 3C, NED 12+ years after interferon and no scans

      • November 1, 2013 at 2:11 pm
      sharon0803
      Participant

      Great question!  I too wondered about this.

       

      • November 1, 2013 at 2:11 pm
      sharon0803
      Participant

      Great question!  I too wondered about this.

       

      • November 1, 2013 at 6:18 pm
      Janner
      Participant

      Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

        • November 1, 2013 at 8:16 pm
        SBeattie
        Participant

        Thank you!

        • November 1, 2013 at 8:16 pm
        SBeattie
        Participant

        Thank you!

        • November 1, 2013 at 8:16 pm
        SBeattie
        Participant

        Thank you!

      • November 1, 2013 at 6:18 pm
      Janner
      Participant

      Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

      • November 1, 2013 at 6:18 pm
      Janner
      Participant

      Mitosis (in some circles) is still a bit controversial because if something is invasive, it implies that some mitosis exists.  In addition, it really depends what sample of tissue you look at.  Right now, it's only used in staging to distinguish between stage IA and stage IB.  It's really a newer prognostic factor and depth, to date, is still THE most important prognostic factor.   

Viewing 5 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.