IPI and abdominal pain
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

IPI and abdominal pain

› Forums › General Melanoma Community › IPI and abdominal pain

  • Post
    • August 16, 2011 at 2:47 am
    mclaus23
    Participant

    Hi All,

     

    My dad, Stage IV mel with mets in the adrenal glands, began ipi 5 days ago. He is in extreme abdominal pain and had night sweats last night. Dr says this is an indication the ipi is working. Has anyone here had  this experience?

    He also said the tumor on his groin is slightly inflamed and sensitive to touch.

     

    Thanks in advance for your input!

    Maggie

    Hi All,

     

    My dad, Stage IV mel with mets in the adrenal glands, began ipi 5 days ago. He is in extreme abdominal pain and had night sweats last night. Dr says this is an indication the ipi is working. Has anyone here had  this experience?

    He also said the tumor on his groin is slightly inflamed and sensitive to touch.

     

    Thanks in advance for your input!

    Maggie

Viewing 5 reply threads
  • Replies
      • August 16, 2011 at 11:40 am
      Lisa13
      Participant

      Hi Maggie,

      That is definately a quick response!  I just started ipi as well 6 days ago and have experienced nothing. My Dr. said I shouldn't feel any side effects this early, but everyone is different.  I really hope this is a good indication that the ipi is working for your Dad. 

      Best of luck!

      Lisa

      • August 16, 2011 at 11:40 am
      Lisa13
      Participant

      Hi Maggie,

      That is definately a quick response!  I just started ipi as well 6 days ago and have experienced nothing. My Dr. said I shouldn't feel any side effects this early, but everyone is different.  I really hope this is a good indication that the ipi is working for your Dad. 

      Best of luck!

      Lisa

      • August 16, 2011 at 2:56 pm
      KatyWI
      Participant

      Abdominal pain can be a side effect of ipi and can indicate colitis.  There does appear to be an association between occurence of side effects and response.  Regardless, "extreme" abdominal pain still needs to be addressed.  Is the doctor doing anything about his pain?

      KatyWI

      • August 16, 2011 at 2:56 pm
      KatyWI
      Participant

      Abdominal pain can be a side effect of ipi and can indicate colitis.  There does appear to be an association between occurence of side effects and response.  Regardless, "extreme" abdominal pain still needs to be addressed.  Is the doctor doing anything about his pain?

      KatyWI

      • August 16, 2011 at 11:15 pm
      Dynasysman
      Participant

      Hi Maggie —

      A week into IPI therapy, I began to experience a fairly strong rash on my forearms.  The next day, we excised a tumor from my neck.  Pathology showed strongly increased lymphocyte presence and only a small area of focal activity (I think that means my white cells were killing the tumor).

      From what I understand, tumors responding to ipi can swell for a while as the white cells arrive to fight the melanoma.  His results may actually be quite encouraging.

      Best of luck and wishes of success for him, and for you.

      • August 16, 2011 at 11:15 pm
      Dynasysman
      Participant

      Hi Maggie —

      A week into IPI therapy, I began to experience a fairly strong rash on my forearms.  The next day, we excised a tumor from my neck.  Pathology showed strongly increased lymphocyte presence and only a small area of focal activity (I think that means my white cells were killing the tumor).

      From what I understand, tumors responding to ipi can swell for a while as the white cells arrive to fight the melanoma.  His results may actually be quite encouraging.

      Best of luck and wishes of success for him, and for you.

        • August 16, 2011 at 11:43 pm
        mclaus23
        Participant

        I thank everyone for your input and help!

        We greatly appreciate it.

        As of right now he feels much better than yesterday, though very tired. The abdominal pain has diminished greatly. He said he had never experienced pain like that in his life.

        I wish you all the best of luck, I'm praying for you all!
        Definitely keep me informed on your journey with ipi

         

        PS- You WILL make your anniversary!!! 

        • August 16, 2011 at 11:43 pm
        mclaus23
        Participant

        I thank everyone for your input and help!

        We greatly appreciate it.

        As of right now he feels much better than yesterday, though very tired. The abdominal pain has diminished greatly. He said he had never experienced pain like that in his life.

        I wish you all the best of luck, I'm praying for you all!
        Definitely keep me informed on your journey with ipi

         

        PS- You WILL make your anniversary!!! 

Viewing 5 reply threads
  • You must be logged in to reply to this topic.
About the MRF Patient Forum

The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

Popular Topics