“atypical melanocytic proliferation” pathology
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“atypical melanocytic proliferation” pathology

› Forums › General Melanoma Community › “atypical melanocytic proliferation” pathology

  • Post
    • May 9, 2015 at 7:13 pm
    looptwelve
    Participant

    Hey everyone,

    I have a quick question on my pathlogy report. I know these questions are fairly common on here, so please bear with me.

    My question is, I've commonly seen "atypical melanocytic cells" used to describe a dysplastic nevus not MIS. Is this truly a MIS nevus or is it dysplastic but trending toward melanoma? What's the distinction between the two?

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  • Replies
      • May 9, 2015 at 7:13 pm
      looptwelve
      Participant

      This post kept triggering the spam filter, so here is the actual pathlogy report:

      "DIAGNOSIS: (NOTE)

      A) UPPER BACK

      Melanoma in situ, peripheral tissue margin involved.



      MICROSCOPIC DESCRIPTION:

      (NOTE)

      A) Sections of skin show a proliferation a atypical melanocytic

      cells aligned along the dermal/epidermal junction and extending

      individually into the upper epidermal layers. Multiple additional

      sections have been examined.



      STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

      peripheral tissue margin.

      COMMENTS:

      Lesion grossly appears to cover the majority of the skin surface.

      Bisected and entirely submitted."

        • May 9, 2015 at 11:04 pm
        Janner
        Participant

        So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

        • May 9, 2015 at 11:04 pm
        Janner
        Participant

        So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

        • May 9, 2015 at 11:04 pm
        Janner
        Participant

        So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

      • May 9, 2015 at 7:13 pm
      looptwelve
      Participant

      This post kept triggering the spam filter, so here is the actual pathlogy report:

      "DIAGNOSIS: (NOTE)

      A) UPPER BACK

      Melanoma in situ, peripheral tissue margin involved.



      MICROSCOPIC DESCRIPTION:

      (NOTE)

      A) Sections of skin show a proliferation a atypical melanocytic

      cells aligned along the dermal/epidermal junction and extending

      individually into the upper epidermal layers. Multiple additional

      sections have been examined.



      STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

      peripheral tissue margin.

      COMMENTS:

      Lesion grossly appears to cover the majority of the skin surface.

      Bisected and entirely submitted."

      • May 9, 2015 at 7:13 pm
      looptwelve
      Participant

      This post kept triggering the spam filter, so here is the actual pathlogy report:

      "DIAGNOSIS: (NOTE)

      A) UPPER BACK

      Melanoma in situ, peripheral tissue margin involved.



      MICROSCOPIC DESCRIPTION:

      (NOTE)

      A) Sections of skin show a proliferation a atypical melanocytic

      cells aligned along the dermal/epidermal junction and extending

      individually into the upper epidermal layers. Multiple additional

      sections have been examined.



      STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

      peripheral tissue margin.

      COMMENTS:

      Lesion grossly appears to cover the majority of the skin surface.

      Bisected and entirely submitted."

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