MRF-Logo2019-Horizontal-RGB
“atypical melanocytic proliferation” pathology
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

“atypical melanocytic proliferation” pathology

› Forums › General Melanoma Community › “atypical melanocytic proliferation” pathology

  • Post
    • May 9, 2015 at 7:13 pm
    looptwelve
    Participant

      Hey everyone,

      I have a quick question on my pathlogy report. I know these questions are fairly common on here, so please bear with me.

      My question is, I've commonly seen "atypical melanocytic cells" used to describe a dysplastic nevus not MIS. Is this truly a MIS nevus or is it dysplastic but trending toward melanoma? What's the distinction between the two?

    Viewing 2 reply threads
    • Replies
        • May 9, 2015 at 7:13 pm
        looptwelve
        Participant

          This post kept triggering the spam filter, so here is the actual pathlogy report:

          "DIAGNOSIS: (NOTE)

          A) UPPER BACK

          Melanoma in situ, peripheral tissue margin involved.



          MICROSCOPIC DESCRIPTION:

          (NOTE)

          A) Sections of skin show a proliferation a atypical melanocytic

          cells aligned along the dermal/epidermal junction and extending

          individually into the upper epidermal layers. Multiple additional

          sections have been examined.



          STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

          peripheral tissue margin.

          COMMENTS:

          Lesion grossly appears to cover the majority of the skin surface.

          Bisected and entirely submitted."

            • May 9, 2015 at 11:04 pm
            Janner
            Participant

              So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

              • May 9, 2015 at 11:04 pm
              Janner
              Participant

                So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

                • May 9, 2015 at 11:04 pm
                Janner
                Participant

                  So, atypical melanocytic cells could describe both MIS or a dysplastic Nevis.  It's a matter of degrees along with analyzing the other factors.  they look at all the factors like architecture and cell atypical and other things to come up with a final diagnosis.  It's a matter of degrees and in some instances, there isn't a lot of difference between the two diagnoses.

                • May 9, 2015 at 7:13 pm
                looptwelve
                Participant

                  This post kept triggering the spam filter, so here is the actual pathlogy report:

                  "DIAGNOSIS: (NOTE)

                  A) UPPER BACK

                  Melanoma in situ, peripheral tissue margin involved.



                  MICROSCOPIC DESCRIPTION:

                  (NOTE)

                  A) Sections of skin show a proliferation a atypical melanocytic

                  cells aligned along the dermal/epidermal junction and extending

                  individually into the upper epidermal layers. Multiple additional

                  sections have been examined.



                  STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

                  peripheral tissue margin.

                  COMMENTS:

                  Lesion grossly appears to cover the majority of the skin surface.

                  Bisected and entirely submitted."

                  • May 9, 2015 at 7:13 pm
                  looptwelve
                  Participant

                    This post kept triggering the spam filter, so here is the actual pathlogy report:

                    "DIAGNOSIS: (NOTE)

                    A) UPPER BACK

                    Melanoma in situ, peripheral tissue margin involved.



                    MICROSCOPIC DESCRIPTION:

                    (NOTE)

                    A) Sections of skin show a proliferation a atypical melanocytic

                    cells aligned along the dermal/epidermal junction and extending

                    individually into the upper epidermal layers. Multiple additional

                    sections have been examined.



                    STAGE (AJCC, 7th Ed, 2010): pTis, pNX, pMX The lesion involves the

                    peripheral tissue margin.

                    COMMENTS:

                    Lesion grossly appears to cover the majority of the skin surface.

                    Bisected and entirely submitted."

                Viewing 2 reply threads
                • You must be logged in to reply to this topic.
                About the MRF Patient Forum

                The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                Popular Topics