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This is the ONLY warning on Amgen’s website – One patient had to have an amputation?????? I think more like hundreds of Patients! This is NOT adequate Amgen!!!!!!

5.3 Injection Site Complications
Necrosis or ulceration of tumor tissue may occur during IMLYGIC treatment. Cellulitis and systemic
bacterial infection have been reported in clinical studies. Careful wound care and infection precautions
are recommended, particularly if tissue necrosis results in open wounds.
In clinical studies, impaired healing at the injection site has been reported. IMLYGIC may increase the
risk of impaired healing in patients with underlying risk factors (e.g., previous radiation at the injection
site or lesions in poorly vascularized areas). One patient had an amputation of a lower extremity 6 months
after IMLYGIC injection due to an infected non-healing wound. This wound area had been treated with
surgery and radiation prior to IMLYGIC treatment and had previous wound complications.

Paul, thanks for your reply about the T-Vec.  Yes, it is working like it is supposed to but, as with all trial proceedures, we did not know what the outcome would be, which was the tumor breaking its way through the skin and making a huge open wound that leeks and will not heal.  I believe now, that  it works better on smaller tumors vs large, as the leg fluid has no where to go due to so many lymph nodes having been removed in his stomach area in previous surgeries. Praying our trip to Rochester Mayo will give us more options.     Kathy

Paul, thanks for your reply about the T-Vec.  Yes, it is working like it is supposed to but, as with all trial proceedures, we did not know what the outcome would be, which was the tumor breaking its way through the skin and making a huge open wound that leeks and will not heal.  I believe now, that  it works better on smaller tumors vs large, as the leg fluid has no where to go due to so many lymph nodes having been removed in his stomach area in previous surgeries. Praying our trip to Rochester Mayo will give us more options.     Kathy

Paul, thanks for your reply about the T-Vec.  Yes, it is working like it is supposed to but, as with all trial proceedures, we did not know what the outcome would be, which was the tumor breaking its way through the skin and making a huge open wound that leeks and will not heal.  I believe now, that  it works better on smaller tumors vs large, as the leg fluid has no where to go due to so many lymph nodes having been removed in his stomach area in previous surgeries. Praying our trip to Rochester Mayo will give us more options.     Kathy

thanks Maria for your input, we have an upcoming appointment at the Mayo which should give us more options.  -Blessings

thanks Maria for your input, we have an upcoming appointment at the Mayo which should give us more options.  -Blessings

thanks Maria for your input, we have an upcoming appointment at the Mayo which should give us more options.  -Blessings

Niki, thanks for your reply and the link to the sciencedirect article, this gives us hope that there is a way to get this done if we keep searching.  I will share the article with Dr Markovic at Mayo Clinic Rochester when we meet with him February 10th.  So grateful to find this forum with such wonderful caring people.  e-hugs right back at you!!!  Kathy

Niki, thanks for your reply and the link to the sciencedirect article, this gives us hope that there is a way to get this done if we keep searching.  I will share the article with Dr Markovic at Mayo Clinic Rochester when we meet with him February 10th.  So grateful to find this forum with such wonderful caring people.  e-hugs right back at you!!!  Kathy

Niki, thanks for your reply and the link to the sciencedirect article, this gives us hope that there is a way to get this done if we keep searching.  I will share the article with Dr Markovic at Mayo Clinic Rochester when we meet with him February 10th.  So grateful to find this forum with such wonderful caring people.  e-hugs right back at you!!!  Kathy

His stage was a I, but our GP family doctor didn't refer us to an Oncologist, had his friend, a woman surgeon do the first surgery.  THAT WAS A HUGE MISTAKE!!!

His stage was a I, but our GP family doctor didn't refer us to an Oncologist, had his friend, a woman surgeon do the first surgery.  THAT WAS A HUGE MISTAKE!!!

His stage was a I, but our GP family doctor didn't refer us to an Oncologist, had his friend, a woman surgeon do the first surgery.  THAT WAS A HUGE MISTAKE!!!