mahdusia
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mahdusia

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      • June 4, 2011 at 6:35 pm
      mahdusia
      Participant

      Michelle,

      do you have any news about the compassionate use of plx4032?

      Did you also check the plx trials in Switzerland – they acccept people with advanced tumors and high liver disfunction  – so maybe it'd be worth trying?

      regards

      Magda

      • June 4, 2011 at 6:35 pm
      mahdusia
      Participant

      Michelle,

      do you have any news about the compassionate use of plx4032?

      Did you also check the plx trials in Switzerland – they acccept people with advanced tumors and high liver disfunction  – so maybe it'd be worth trying?

      regards

      Magda

      • June 6, 2011 at 3:55 am
      mahdusia
      Participant

      Michelle,

      this is the link for Switzerland trial:
       

      http://www.roche-trials.com/trialDetailsGet.action?studyNumber=MO25653&productGenericName=RO5185426&productType=Drug

       

      I have also the e-mail for coordinator, I can send you to your private e-mail – I got it from Shelly.

      Your husband is treated in Massachusets General, isn't he?

      regards

      Magda

      • June 6, 2011 at 3:55 am
      mahdusia
      Participant

      Michelle,

      this is the link for Switzerland trial:
       

      http://www.roche-trials.com/trialDetailsGet.action?studyNumber=MO25653&productGenericName=RO5185426&productType=Drug

       

      I have also the e-mail for coordinator, I can send you to your private e-mail – I got it from Shelly.

      Your husband is treated in Massachusets General, isn't he?

      regards

      Magda

      • May 31, 2011 at 11:51 pm
      mahdusia
      Participant

      Michelle,

      that is thrilling news! Would you be so kind to give me some direct contact/site where this trial is going to be organized?

      And also one, maybe silly question. I am not the native English-speaker and I am not familiar with the practical meaning of word "compassionate" in terms of clinical trials…

      Could you please explain me how it works?

      • May 31, 2011 at 11:51 pm
      mahdusia
      Participant

      Michelle,

      that is thrilling news! Would you be so kind to give me some direct contact/site where this trial is going to be organized?

      And also one, maybe silly question. I am not the native English-speaker and I am not familiar with the practical meaning of word "compassionate" in terms of clinical trials…

      Could you please explain me how it works?

      • May 31, 2011 at 11:45 pm
      mahdusia
      Participant

      Frank,

      we checked the liver functions almost day by day and it's not that bad (ALT, AST, LDH over the limit, but it's less than a week ago).

      the problem with Yervoy, in opinion of my doctor, was my father's brain surgery two weeks ago

      the doctor told us that after the craniotomy (one of tumors ulcerated, another, very small, still in there) there is a big risk of stroke while taking Yervoy and refused to give him that medicine 🙁

      • May 31, 2011 at 11:45 pm
      mahdusia
      Participant

      Frank,

      we checked the liver functions almost day by day and it's not that bad (ALT, AST, LDH over the limit, but it's less than a week ago).

      the problem with Yervoy, in opinion of my doctor, was my father's brain surgery two weeks ago

      the doctor told us that after the craniotomy (one of tumors ulcerated, another, very small, still in there) there is a big risk of stroke while taking Yervoy and refused to give him that medicine 🙁

      • May 31, 2011 at 12:08 pm
      mahdusia
      Participant

      Big thanks to all for sending me the additional info. I will go through all the sites and check whether sg is available for him.

      Answering all the questions I got:

      – my father was treated by the doctor, who is quite famous melanoma specialist and I am pretty disappointed in his approach. I just got the feeling that he sticks to the methods which are "officially accepted" and doesn't want to take the risk of trying something new. In the situation when you practically have nothing to lose, he should have been a little more flexible. As a result, I am searching all the databases for clinical trials without any professional support.

      – the mixed chemo we were proposed is: cisplastin, vinblastin, and temozolomide.

       

      • May 31, 2011 at 12:08 pm
      mahdusia
      Participant

      Big thanks to all for sending me the additional info. I will go through all the sites and check whether sg is available for him.

      Answering all the questions I got:

      – my father was treated by the doctor, who is quite famous melanoma specialist and I am pretty disappointed in his approach. I just got the feeling that he sticks to the methods which are "officially accepted" and doesn't want to take the risk of trying something new. In the situation when you practically have nothing to lose, he should have been a little more flexible. As a result, I am searching all the databases for clinical trials without any professional support.

      – the mixed chemo we were proposed is: cisplastin, vinblastin, and temozolomide.

       

      • May 24, 2011 at 5:41 pm
      mahdusia
      Participant

      Shelly

      My father has a MM, stage IV with brain lesions. I just found the information about the clinical trial on RO5185426 and I'd absolutely appreciate the details how to get to/be approved etc. He is B-Raf positive.

       

      Looking forward to hearing from you

      Magda

      • May 24, 2011 at 5:41 pm
      mahdusia
      Participant

      Shelly

      My father has a MM, stage IV with brain lesions. I just found the information about the clinical trial on RO5185426 and I'd absolutely appreciate the details how to get to/be approved etc. He is B-Raf positive.

       

      Looking forward to hearing from you

      Magda

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