Jess58

Yes, my wife is treating at Sylvester Comprehensive Cancer Unit at the University of Miami. I checked out the closest NCI affiliate and it’s in Tampa -Moffit. I tried getting my wife in some trials there but the wouldn’t take her.

Thanks for the advice.

Thank you for the information. I will pass it on to my wife.

I hope the Abraxane actually reverses some of the progression but will take any positive effect also. So if it just slows it so we buy time for something else to come along then so be it.

This is such a hardcore illness to deal with and we pray daily to the Lord for help.

It’s helpful to know that the Abraxane may be easier to deal with side effects wise.

I wish you of the best of luck with your mother.

Warm regards

Jess

Jess

Thanks for all the information most kind of you.

Got a call from my wife’s doctor today and he said that the MRI showEd new metastasis to two vertebraes. So now he’s talking about radiation to ease the pain and he’s also talking in about adding some chemo. Perhaps a nab-paclitaxel. He also may keep the leukine in there but he’s waiting on insurance approvals for that. I spoke to him about bringing in a follicular lymphoma consultant and he said he had no problems with doing that.

So we will be Consulting with the head doctor that’s handling the melanoma treatment and then another physician for the radiation and then another for the follicular lymphoma and mixing and all sorts of drugs, keytruda, leukine, nab-paclitaxel and radiation.

I know that they say that you have to be very aggressive with concurrent diseases but this is a lot.

We are hanging tough. And positive. We believe you never know when it’s tweaked right and good things start happening.

Jess

Thanks for all the information most kind of you.

Got a call from my wife’s doctor today and he said that the MRI showEd new metastasis to two vertebraes. So now he’s talking about radiation to ease the pain and he’s also talking in about adding some chemo. Perhaps a nab-paclitaxel. He also may keep the leukine in there but he’s waiting on insurance approvals for that. I spoke to him about bringing in a follicular lymphoma consultant and he said he had no problems with doing that.

So we will be Consulting with the head doctor that’s handling the melanoma treatment and then another physician for the radiation and then another for the follicular lymphoma and mixing and all sorts of drugs, keytruda, leukine, nab-paclitaxel and radiation.

I know that they say that you have to be very aggressive with concurrent diseases but this is a lot.

We are hanging tough. And positive. We believe you never know when it’s tweaked right and good things start happening.

Jess

Please forgive me as I am getting my feet wet in this process and sorry that I’m posting as anonymous. I am on the site as Jess58.

Yes I meant leukine.

The doctor said she’d be receiving injections at home and the keytruda will be infused at the hospital facilities. Still don’t know how the injections will be given on her body. I guess the doctor will explain that on the 15th. My wife hopes that they don’t expect me to inject her although I’m willing and capable but she’s concerned with the situs of the injection and is not thrilled with me having to inject her visible tumors. She’s also concerned with the pain that would be involved with an injection at the tumor site but I tell her if that’s what it takes then that’s what it takes.

Do you know if they use topical anesthetics or do they do it cold turkey? This is all so new and I feel like we’re playing catch-up.

I don’t know if a nurse comes to the house and injects her. I don’t have a clue all I know is that the doctor said daily injections at home.

Yes I read the same article about the CD 10 expression and how it fights to keep the melanoma alive and progressing. I also read that researches indicate that that expression should serve as a Target and that perhaps a cleavable peptide prodrug is the way to go with those expressions. One such drug I believe it’s called doxorubicin.

She has follicular lymphoma too and I know that they use rituxan which is a prodrug but her doctor told us that that targets the cd20 expression which she does not have.

Hopefully this new combination will be a success but like to have a plan C&D in the works.

Another doctor indicated a good second line would be a abraxene which is a nab-paclitaxel chemo drug.

Let me just say this is one scary disease.

Her lymph nodes swell up then they go down. She has pain roving all over her back, on her neck under her arm and even in her groin. It just jumps around all the time and in no one fixed place.

She also had nausea which has gotten much better now, fevers which I’ve gotten better now ,chills which I’ve gotten better, and night sweats better now, and bloating. Some vomiting. But no diarrhea thank God. No skin rashes either.

We stay positive and have great faith that God will help our family.

I am so glad I found this site as it is so helpful and full of support and those that contribute do a wonderful thing to help others in need. To all those out there fight on.

I am trying to digestion comprehend the wonderful information that you supplied to me and again thank you for it.

Any information on the peptide prodrug and cd10 expression would be appreciated as well as any information on how addressing her follicular lymphoma,b cell might help with the melanoma.

Please forgive me as I am getting my feet wet in this process and sorry that I’m posting as anonymous. I am on the site as Jess58.

Yes I meant leukine.

The doctor said she’d be receiving injections at home and the keytruda will be infused at the hospital facilities. Still don’t know how the injections will be given on her body. I guess the doctor will explain that on the 15th. My wife hopes that they don’t expect me to inject her although I’m willing and capable but she’s concerned with the situs of the injection and is not thrilled with me having to inject her visible tumors. She’s also concerned with the pain that would be involved with an injection at the tumor site but I tell her if that’s what it takes then that’s what it takes.

Do you know if they use topical anesthetics or do they do it cold turkey? This is all so new and I feel like we’re playing catch-up.

I don’t know if a nurse comes to the house and injects her. I don’t have a clue all I know is that the doctor said daily injections at home.

Yes I read the same article about the CD 10 expression and how it fights to keep the melanoma alive and progressing. I also read that researches indicate that that expression should serve as a Target and that perhaps a cleavable peptide prodrug is the way to go with those expressions. One such drug I believe it’s called doxorubicin.

She has follicular lymphoma too and I know that they use rituxan which is a prodrug but her doctor told us that that targets the cd20 expression which she does not have.

Hopefully this new combination will be a success but like to have a plan C&D in the works.

Another doctor indicated a good second line would be a abraxene which is a nab-paclitaxel chemo drug.

Let me just say this is one scary disease.

Her lymph nodes swell up then they go down. She has pain roving all over her back, on her neck under her arm and even in her groin. It just jumps around all the time and in no one fixed place.

She also had nausea which has gotten much better now, fevers which I’ve gotten better now ,chills which I’ve gotten better, and night sweats better now, and bloating. Some vomiting. But no diarrhea thank God. No skin rashes either.

We stay positive and have great faith that God will help our family.

I am so glad I found this site as it is so helpful and full of support and those that contribute do a wonderful thing to help others in need. To all those out there fight on.

I am trying to digestion comprehend the wonderful information that you supplied to me and again thank you for it.

Any information on the peptide prodrug and cd10 expression would be appreciated as well as any information on how addressing her follicular lymphoma,b cell might help with the melanoma.