HI maria, I have never posted anything on a chat room before … but having read your message I felt compelled to. I think your messagae is from a long time ago, but I wanted to share my husbands story with you as he has the same mutation. D has mucosal melanoma originating in the bowel and diagnosed in Nov 15 To cut a long story short within the space of a year it had spread to many places, despite having had extensive amounts of immuno (ipinivo combi) – from which the side effects were severe and he was hospitalised for much of last year. Anyway, now comes the most relevant bit – the immuno hadn't worked so our oncologist switched Dom to a targetted therapy called Gleevec (also called imitinab I think) due to his C-Kit mutation – its a drug usually used in Lukemia. Anyway, within 6 weeks the cancer had completely regressed (from around 6 different parts of his body) and 6 months later, the cancer hasn't learnt its way round the drug – it has felt like a total miracle. Our oncologiest also says there are a number of sister drugs we can then try if there is 'break through' against with this drug. Anyway, its not usually used in mm, so I wanted to share this success story in the hope it could help you if needed or someone else with a c-kit mutation.
