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Yervoy / Ipi itching!
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Yervoy / Ipi itching!

› Forums › General Melanoma Community › Yervoy / Ipi itching!

  • Post
    • March 16, 2014 at 2:02 am
    heiditemple
    Participant

      I am in clinical trial E1609 and I am scheduled to receive my 3rd infusion on Tuesday.  I am getting 10mg/kg.  Almost immediately after the 2nd infusion, the itching began almost immediately!  I'm not worried about it because I know it's a common side effect, but I'm wondering if there is anything else anyone else has done other than just take Benadryl.  Benadryl definitely helps, but if I forget to take it every 3-4 hours, the itching starts like clockwork.  Thanks!

    Viewing 5 reply threads
    • Replies
        • March 16, 2014 at 2:45 am
        Marianne quinn
        Participant

          My hubby uses lotion frequently and rubs it in. He takes loratidine 10 mg during the day because it is non-sedating. Fleece and warm clothing  make it worse. Avoid grass and sawdust . The itching gets better. He had his 4 the infusion 10 days ago.

          He  had a lot of cramping after 3rd infusion. It stopped when he quit milk and ice cream. Doing very well now

            • March 16, 2014 at 11:16 am
            tschmith
            Participant

              I've read that a lotion called Sarna (might be spelled incorrectly) is very helpful.  I've seen it at CVS so you don't need a prescription.

              • March 16, 2014 at 11:16 am
              tschmith
              Participant

                I've read that a lotion called Sarna (might be spelled incorrectly) is very helpful.  I've seen it at CVS so you don't need a prescription.

                • March 16, 2014 at 11:16 am
                tschmith
                Participant

                  I've read that a lotion called Sarna (might be spelled incorrectly) is very helpful.  I've seen it at CVS so you don't need a prescription.

                • March 16, 2014 at 2:45 am
                Marianne quinn
                Participant

                  My hubby uses lotion frequently and rubs it in. He takes loratidine 10 mg during the day because it is non-sedating. Fleece and warm clothing  make it worse. Avoid grass and sawdust . The itching gets better. He had his 4 the infusion 10 days ago.

                  He  had a lot of cramping after 3rd infusion. It stopped when he quit milk and ice cream. Doing very well now

                  • March 16, 2014 at 2:45 am
                  Marianne quinn
                  Participant

                    My hubby uses lotion frequently and rubs it in. He takes loratidine 10 mg during the day because it is non-sedating. Fleece and warm clothing  make it worse. Avoid grass and sawdust . The itching gets better. He had his 4 the infusion 10 days ago.

                    He  had a lot of cramping after 3rd infusion. It stopped when he quit milk and ice cream. Doing very well now

                    • March 16, 2014 at 1:07 pm
                    katie1
                    Participant

                      My husband is in the same trial.  He too developed itching early on and 7 months since his last dose (3mg/kg) still has itching. He still uses Benadryl regularly. He also has rashes for which he uses hydrocortisone cream and that also seems to help the itching (in places where rash and itching overlap). He no longer seems to find Benadryl sedating (during the day he now only takes 25mg). I'll be curious to hear what others have found useful.  

                      Kate

                      • March 16, 2014 at 1:07 pm
                      katie1
                      Participant

                        My husband is in the same trial.  He too developed itching early on and 7 months since his last dose (3mg/kg) still has itching. He still uses Benadryl regularly. He also has rashes for which he uses hydrocortisone cream and that also seems to help the itching (in places where rash and itching overlap). He no longer seems to find Benadryl sedating (during the day he now only takes 25mg). I'll be curious to hear what others have found useful.  

                        Kate

                        • March 16, 2014 at 1:07 pm
                        katie1
                        Participant

                          My husband is in the same trial.  He too developed itching early on and 7 months since his last dose (3mg/kg) still has itching. He still uses Benadryl regularly. He also has rashes for which he uses hydrocortisone cream and that also seems to help the itching (in places where rash and itching overlap). He no longer seems to find Benadryl sedating (during the day he now only takes 25mg). I'll be curious to hear what others have found useful.  

                          Kate

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