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Viagra linked to melanoma??

Forums General Melanoma Community Viagra linked to melanoma??

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      shanemcdonald99
      Participant

        you better stop taking it then Ginger !

        lol

         

        shane

         

        had some fatigue and weakness this week from Yervoy, but not too bad.

        Next week is infusion 2

        shanemcdonald99
        Participant

          you better stop taking it then Ginger !

          lol

           

          shane

           

          had some fatigue and weakness this week from Yervoy, but not too bad.

          Next week is infusion 2

            Ginger8888
            Participant

              Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

              Ginger8888
              Participant

                Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

                Ginger8888
                Participant

                  Haha!! I don't need it..lol..My first infusion of Yervoy was last week..Blood work tomorrow and next treatment is July 3..Good luck

                  JamesH
                  Participant

                    Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

                    Melanoma cancer may just be the start of what is to come for Vigra!!!  

                    JamesH
                    Participant

                      Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

                      Melanoma cancer may just be the start of what is to come for Vigra!!!  

                      JamesH
                      Participant

                        Melanoma is very nasty. Many of you know this much better than I do.  This really is not a joke!

                        Melanoma cancer may just be the start of what is to come for Vigra!!!  

                      shanemcdonald99
                      Participant

                        you better stop taking it then Ginger !

                        lol

                         

                        shane

                         

                        had some fatigue and weakness this week from Yervoy, but not too bad.

                        Next week is infusion 2

                        joelcairo
                        Participant

                          Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

                          Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

                          BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

                           

                            Ginger8888
                            Participant

                              Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

                              Ginger8888
                              Participant

                                Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

                                Ginger8888
                                Participant

                                  Something to think and ask about, not sure where they're going with it, i just seen this on one of my facebook pages and thought i'd share it..I hope it's helpful..

                                  JamesH
                                  Participant

                                    Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

                                    If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

                                    Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

                                    It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

                                    If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

                                    JamesH
                                    Participant

                                      Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

                                      If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

                                      Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

                                      It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

                                      If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

                                      JamesH
                                      Participant

                                        Joel. You would be surprised how much actually went into the study to analyze variables such as those you mention.  You can read more about the actual study here:  JAMA Harvard Viagra Melanoma Study

                                        If you would like a toned down version…  The study took into account many outside factors including family history, uv exposure and other variables. 

                                        Viagra, Levitra and Cialis are designed to block/ inhibit PDE5 which otherwise would restrict blood flow to the penis. Maybe what happens is that PDE5 also slows down blood flow to melanoma cells that would otherwise never spread?  It is possible…  The study shows an 84% increase in men's risk of melanoma. It was a study from Harvard… Not too shabby…  It included over 25,000 men… Certainly more than a handful… 

                                        It is told that sunburns can double your melanoma risks.  IT WAS NOT ON VIAGRA's LABEL!

                                        If you know anyone who this might apply to, check out this:  http://www.viagramelanomaattorney.com

                                      joelcairo
                                      Participant

                                        Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

                                        Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

                                        BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

                                         

                                        joelcairo
                                        Participant

                                          Not sure what to make of this study. Unfortunately I can only see the abstract. It seems sound, but I wonder if the researchers were really able to account for confounding factors, such as Viagra use being generally associated with increasing age and poor blood circulation.

                                          Also grouping patients into two categories of "ever used" and "never used" seems overly crude. It would be better to see a graph demonstrating a trend of increased use leading to increased risk. Perhaps that would require a larger study.

                                          BTW, I'm troubled mainly because Viagra has also been associated with some cancer protective activities such as reducing inflammation and reducing immunosuppression. It may be that the negatives outweigh the positives.

                                           

                                          Janner
                                          Participant

                                            Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

                                            Janner
                                            Participant

                                              Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

                                              Janner
                                              Participant

                                                Personally, I think it's a flawed study to start with.  THE most likely population to get melanoma is older men (even before Viagra).  The most likely population to use Viagra is older men.  Correlation is not cause.

                                                  Ginger8888
                                                  Participant

                                                    Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

                                                    Ginger8888
                                                    Participant

                                                      Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

                                                      Ginger8888
                                                      Participant

                                                        Good point.. I don't anything about Viagra and am new to the melanoma world so i'm still learning new things everyday..

                                                        WOStavelot
                                                        Participant

                                                          Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

                                                          The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

                                                          When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

                                                          The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

                                                          Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

                                                          Does an attorney you know take Viagra? One could hope so …

                                                          WOStavelot
                                                          Participant

                                                            Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

                                                            The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

                                                            When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

                                                            The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

                                                            Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

                                                            Does an attorney you know take Viagra? One could hope so …

                                                            joelcairo
                                                            Participant

                                                              Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

                                                              Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

                                                               

                                                              joelcairo
                                                              Participant

                                                                Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

                                                                Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

                                                                 

                                                                joelcairo
                                                                Participant

                                                                  Thank you for linking to the full study under discussion. It's true that the health status of the participants was considered, but excluding major chonic diseases does not completely account for what must be a powerful correlation between Viagra use and generally poorer health by some measures.

                                                                  Also, in some studies Viagra has been shown to reduce inflammation and reduce inflammation-related immunosppression. So it's possible there could be two countervailing effects at work here.

                                                                   

                                                                  WOStavelot
                                                                  Participant

                                                                    Personally, I wonder if those wrting here have read the study. Not only does it address all the concerns voiced here, which are valid, but for me it fits perfectly into all the current evidence coming out of Molecular Biology that relates directly to melanoma. The legal aspects of this don't concern me, but I doubt that was an issue when these investigators formulated their hypothesis.

                                                                    The "numbers" are more than adequate when one reads the report. "Big numbers," which this study has, aren't the goal nor the final determinant of value in medical research : it's usually investigator insight.

                                                                    When Alexander Breslow, (I had the pleasure and true opportunity of being one of his students), reported in 1969 on the importance of thickness in cutaneous melanomas, he did so quite humbly, based on 98 patients at GW. Not a huge number when compared with meta-analyses commonly seen today. But his results remain one of the guiding lights of Staging and Prognosis in melanoma care. By comparison, many huge meta-analyses have come and gone with the wind. But the statistics in his "little study" were good and supported his claims that cutaneous melanomas less than 0.76 mm thick had neither recurrence nor metastases,and that one could use thickness to predict outcome.

                                                                    The numbers, and conclusions as stated in this study on Viagra and melanoma are good as well.

                                                                    Don't be scared away by all the biomolecular terms for how this medicine, and melanoma initiation "works." It doesn't explain, or try to explain, everything about these relationships. But it's a good study. It teaches more about making inroads into countering melanoma.

                                                                    Does an attorney you know take Viagra? One could hope so …

                                                                    JamesH
                                                                    Participant

                                                                      The same population…  84% increase in melanoma cancer from Viagra.  

                                                                      Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

                                                                      Do you also think the studies showing the suns harmful effects are also skewed? 

                                                                      JamesH
                                                                      Participant

                                                                        The same population…  84% increase in melanoma cancer from Viagra.  

                                                                        Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

                                                                        Do you also think the studies showing the suns harmful effects are also skewed? 

                                                                        JamesH
                                                                        Participant

                                                                          The same population…  84% increase in melanoma cancer from Viagra.  

                                                                          Harvard Medical School is not exactly the least among medical schools and institutions that study skin cancers.  Where did you graduate from?  84% is almost DOUBLE which is what many claim sunburn does to your risk for skin cancer.

                                                                          Do you also think the studies showing the suns harmful effects are also skewed? 

                                                                        JerryfromFauq
                                                                        Participant

                                                                          Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

                                                                          JerryfromFauq
                                                                          Participant

                                                                            Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

                                                                              Ginger8888
                                                                              Participant

                                                                                No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

                                                                                Ginger8888
                                                                                Participant

                                                                                  No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

                                                                                  Ginger8888
                                                                                  Participant

                                                                                    No i'm sorry , i did not read the other attached articles..I really hate when those class acton suits show up…Personally i think they're just out for money..Again i'm sorry i should have looked into it further….

                                                                                  JerryfromFauq
                                                                                  Participant

                                                                                    Also note that the article is for the purpose of trying to start a class action lawsuit for lawyers to collect millions of dollars!

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