› Forums › Cutaneous Melanoma Community › Suspicious for Melonma in Situ
- This topic has 1 reply, 1 voice, and was last updated 5 years, 9 months ago by Treadlightly.
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- July 13, 2018 at 3:10 am
Hi,
I am new to this. I had a biopsy for a mole on my big toe about a month ago. I have a family history of melonoma and have always been careful to stay out of the sun and use sunscreen.The path report came back
FINAL PATHOLOGIC DIAGNOSIS
SKIN, LEFT FIRST TOE, PUNCH BIOPSY:
-ATYPICAL JUNCTIONAL MELANOCYTIC PROLIFERATION, SUSPICIOUS FOR
MELANOMA IN SITU, FOCALLY
TRANSECTED LATERALLY (SEE COMMENT)
-REEXCISION IS ADVISEDNUPOOR ANANT GAJJAR M.D.
** Report Electronically Signed by NAG **
Comment
The clinical images from 7/2017 are reviewed but recent clinical
images are not available for evaluation. The lesion is atypical
given the irregular distribution along the junction (despite the
location being an acral site) and there is suspicion for melanoma
in situ. Therefore, reexcision (with melanoma in situ-type margins)
is advised to ensure complete removal of the entire lesion.
Clinical correlation is advised.Consensus diagnosis: Dr. Jessica Chan
Mic roscopic Description
Sections demonstrate a thick stratum corneum consistent with acral
skin overlying a lentiginous junctional proliferation of
melanocytes. Immunoperoxidase stains Sox-10 and Melan A highlight
melanocytes and show patchy irregular distribution along the
junction with melanocytes focally transected at a peripheral edge of the biopsyWhat does focally transected laterally at the peripheral edge mean? was the
Does it mean there could be more atypical or melonoma cells past the peripheral edge?
I am having surgery next week with the 1/2 cm margins. I am very anxious. I know the success rate is very good if caught early enough. I appreciate all the knowledge and support this bulletin board offers.
I wish this had been around when my mom had melanoma.
Thank you for your support
- Replies
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- July 13, 2018 at 1:30 pm
It sounds to me as though the biospy report is saying that the lesion extended beyond the initial biopsy. It is unusual that there is no mention in the biopsy report of the depth of the invasion of the lesion. However, there is mention of "suspicion of melanoma in situ." It is possible that they need the complete lesion to make the final Breslow's depth determination.
Best of luck for a successful treatment!
Mark 2A
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Tagged: acral, cutaneous melanoma
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