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Suspicious for Melonma in Situ

Forums Cutaneous Melanoma Community Suspicious for Melonma in Situ

  • Post
    mbecker
    Participant

      Hi,

      I am new to this. I had a biopsy for a mole on my big toe about a month ago. I have a family history of melonoma and have always been careful to stay out of the sun and use sunscreen.The path report came back 

      FINAL PATHOLOGIC DIAGNOSIS
      SKIN, LEFT FIRST TOE, PUNCH BIOPSY: 
      -ATYPICAL JUNCTIONAL MELANOCYTIC PROLIFERATION, SUSPICIOUS FOR
      MELANOMA IN SITU, FOCALLY
      TRANSECTED LATERALLY (SEE COMMENT) 
      -REEXCISION IS ADVISED

      NUPOOR ANANT GAJJAR M.D.
      ** Report Electronically Signed by NAG **
      Comment
      The clinical images from 7/2017 are reviewed but recent clinical
      images are not available for evaluation. The lesion is atypical
      given the irregular distribution along the junction (despite the
      location being an acral site) and there is suspicion for melanoma
      in situ. Therefore, reexcision (with melanoma in situ-type margins)
      is advised to ensure complete removal of the entire lesion.
      Clinical correlation is advised.

      Consensus diagnosis: Dr. Jessica Chan

      Mic roscopic Description
      Sections demonstrate a thick stratum corneum consistent with acral
      skin overlying a lentiginous junctional proliferation of
      melanocytes. Immunoperoxidase stains Sox-10 and Melan A highlight
      melanocytes and show patchy irregular distribution along the
      junction with melanocytes focally transected at a peripheral edge of the biopsy

      What does focally transected laterally at the peripheral edge mean? was the 

      Does it mean there could be more atypical or melonoma cells past the peripheral edge?

      I am having surgery next week with the 1/2 cm margins.  I am very anxious. I know the success rate is very good if caught early enough.  I appreciate all the knowledge and support this bulletin board offers.

      I wish this had been around when my mom had melanoma.

      Thank you for your support

       

       

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    • Replies
        Treadlightly
        Participant

          It sounds to me as though the biospy report is saying that the lesion extended beyond the initial biopsy.  It is unusual that there is no mention in the biopsy report of the depth of the invasion of the lesion. However, there is mention of "suspicion of melanoma in situ." It is possible that they need the complete lesion to make the final Breslow's depth determination. 

          Best of luck for a successful treatment!

          Mark 2A

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