› Forums › General Melanoma Community › Seeking input on Yervoy introduction vs maintenance
- This topic has 3 replies, 1 voice, and was last updated 11 years, 12 months ago by Gene_S.
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- May 9, 2012 at 9:16 pm
My husband had four infusions of 5mg of Yervoy Dec 2011 and Jan 2012. His scans in March showed tumors in brain, lungs, pancreas were either gone or inactive. His also has had gamma knife twice in past 8 months which may have contributed to shrinking of bain nets. His doctor was very excited and said he believed my husband was a very positive responder.
My husband had four infusions of 5mg of Yervoy Dec 2011 and Jan 2012. His scans in March showed tumors in brain, lungs, pancreas were either gone or inactive. His also has had gamma knife twice in past 8 months which may have contributed to shrinking of bain nets. His doctor was very excited and said he believed my husband was a very positive responder.
He has developed a large tumor on one lower leg in an area where he had wounds in the past. His onc. is concidering re-introduction. My husband is the only patient on yervoy and has relied on me to keep him updated him and current on yervoy from my research. When I asked why not maintenance rather than a full introduction which might be less destructive on a 72 year old man which heart problems, the doctor stated he was not familiar with maintenance. I have seen several posts about this and wondered how others have done on maintenance vs a complete re-introduction.
It is less than six months from starting the yervoy and considering the onc said he was a good responder I wonder if the yervoy may still be working and maintenance would be less aggressive.
Any thoughts……
Thanking you in advance for your input….
Linda
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- May 10, 2012 at 7:19 pm
Hello Linda,
My husband is on Yervoy (Ipi) Clinical Trial. After he did the 4 doses then every 12 weeks he gets another infusion of Yervoy. This is the way his clinical trial was set up. He is on the 10 mg/kg and he started March 3, 2011. Don't know about your situation as far as introduction or maintenance but was he on a clinical trial? This might be why the difference.
Gene is down to 1 small lesion in the liver that is almost unmeasurable from one that was 5 x 6. All of the others are gone and the one that was pushing on the C1-C2 spine shows new tissue growing replacing the melanoma.
Hope things work out for your husband. I will keep you both in my prayers.
Judy (loving wife and caregiver to Gene)
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- May 10, 2012 at 7:19 pm
Hello Linda,
My husband is on Yervoy (Ipi) Clinical Trial. After he did the 4 doses then every 12 weeks he gets another infusion of Yervoy. This is the way his clinical trial was set up. He is on the 10 mg/kg and he started March 3, 2011. Don't know about your situation as far as introduction or maintenance but was he on a clinical trial? This might be why the difference.
Gene is down to 1 small lesion in the liver that is almost unmeasurable from one that was 5 x 6. All of the others are gone and the one that was pushing on the C1-C2 spine shows new tissue growing replacing the melanoma.
Hope things work out for your husband. I will keep you both in my prayers.
Judy (loving wife and caregiver to Gene)
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- May 10, 2012 at 7:19 pm
Hello Linda,
My husband is on Yervoy (Ipi) Clinical Trial. After he did the 4 doses then every 12 weeks he gets another infusion of Yervoy. This is the way his clinical trial was set up. He is on the 10 mg/kg and he started March 3, 2011. Don't know about your situation as far as introduction or maintenance but was he on a clinical trial? This might be why the difference.
Gene is down to 1 small lesion in the liver that is almost unmeasurable from one that was 5 x 6. All of the others are gone and the one that was pushing on the C1-C2 spine shows new tissue growing replacing the melanoma.
Hope things work out for your husband. I will keep you both in my prayers.
Judy (loving wife and caregiver to Gene)
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