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“58% SR after vervoy + opvido regime after 5 years.” Years ago I saw a similar 5 year SR with Vervoy and opvido as the initial treatment for people with stage 4 melanoma. People with stage 3 should do better.
The numbers come from Checkmate 067, which started in 2014 and patients could not have had Ipilimumab prior which was approved in 2011 time frame. So (untreated) would mean new stage 4 and if you read checkmate 067 clinical trial it goes into more detail of who qualified. Today with adjuvant immunotherapy by the time they are stage 4 they have had either targeted therapy or pd-1 treatment already. Go to result section of following article and you will see where the 945 # comes from. I was one of the 315 in the Nivo arm of the trial. https://www.nejm.org/doi/full/10.1056/NEJMoa1910836https://clinicaltrials.gov/ct2/show/NCT01844505
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