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Question to MEK responders

Forums General Melanoma Community Question to MEK responders

  • Post
    emilypen
    Participant

    Hi All,

    I'm just wondering if anyone on a MEK inhibitor (spefically the GSK MEK if possible) has/had bone mets? and if so did the bone mets respond to the MEK inhibitor any differently than soft tissue tumours?

    My husband has only been on the trial for 7 weeks and the soft tissue tumours are causing no pain whatsever ( and they were pressing on nerves before) but the a few of the areas where we know there are bone mets are causing some pain… so we were thinking maybe they take longer to respond?

    Just interested in anyone else's experiences.

     

    Hi All,

    I'm just wondering if anyone on a MEK inhibitor (spefically the GSK MEK if possible) has/had bone mets? and if so did the bone mets respond to the MEK inhibitor any differently than soft tissue tumours?

    My husband has only been on the trial for 7 weeks and the soft tissue tumours are causing no pain whatsever ( and they were pressing on nerves before) but the a few of the areas where we know there are bone mets are causing some pain… so we were thinking maybe they take longer to respond?

    Just interested in anyone else's experiences.

     

    thanks,

    Em

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  • Replies
      killmel
      Participant

      Hi Em,

      I cannot answer your question but I would be interested in knowing if he has any side effects taking the MEK drug. I am thinking about going on this trial. Thanks for your reply

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      killmel
      Participant

      Hi Em,

      I cannot answer your question but I would be interested in knowing if he has any side effects taking the MEK drug. I am thinking about going on this trial. Thanks for your reply

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      mrsmarilyn
      Participant

      Hi Em-Even though my brother is on the GSK Braf inhibitor – he always hears how great the GSK MEK is working -to the point his Dr's have even asked him if he wanted to switch to MEK?!  Since he is having great success with the GSK Braf- he, of course, does not want to.  But at Sara Cannon– MEK is extremely effective with the group currently enrolled there.

      Hope that helps – keep us posted! Best of luck!

      MrsMarilyn

      sister of Gary (stage IV)

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      mrsmarilyn
      Participant

      Hi Em-Even though my brother is on the GSK Braf inhibitor – he always hears how great the GSK MEK is working -to the point his Dr's have even asked him if he wanted to switch to MEK?!  Since he is having great success with the GSK Braf- he, of course, does not want to.  But at Sara Cannon– MEK is extremely effective with the group currently enrolled there.

      Hope that helps – keep us posted! Best of luck!

      MrsMarilyn

      sister of Gary (stage IV)

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