› Forums › General Melanoma Community › Pathology Report
- This topic has 15 replies, 5 voices, and was last updated 7 years, 12 months ago by BillMFl.
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- December 28, 2016 at 6:45 pm
Hi,
This is my pathology report for in situ: 6x5x1 mm specimen. There is a profilerat6ion of atypical melanocytes present in the epidermis with irregular nests of melanocytes aggregated at the dermoepidermal junction and solitary melanocytes present within the epidermis. The process is confiend to the epidermis. These changes represent primary malignatnt melanoma in situ. Is this pretty standart report for in situ? To me it looks like that there are abnormal melanocytes. Who make the decision if it's in situ or atypical mole? I had this mole slowly growing over 12 years.
It will not change my outcome.. but just wondering… Thanks and appreciate all your help on this forum so far.
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- December 28, 2016 at 7:07 pm
Wow, that is pretty much verbatim how my path report from a week ago read. Mine was in-Situ and I just had my WLE on my neck yesterday. Hopefully, that path report will come back with clear margins so I can get this open wound stitched up tomorrow and not have more taken out.
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- December 28, 2016 at 7:07 pm
Wow, that is pretty much verbatim how my path report from a week ago read. Mine was in-Situ and I just had my WLE on my neck yesterday. Hopefully, that path report will come back with clear margins so I can get this open wound stitched up tomorrow and not have more taken out.
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- December 28, 2016 at 7:07 pm
Wow, that is pretty much verbatim how my path report from a week ago read. Mine was in-Situ and I just had my WLE on my neck yesterday. Hopefully, that path report will come back with clear margins so I can get this open wound stitched up tomorrow and not have more taken out.
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- December 28, 2016 at 7:21 pm
It's a matter of degrees. The is just more cellular atypia or architectural atypia in melanoma in situ than a dysplastic mole. They look at a lot of factors and at some point, it crosses the line to a lesion that has the potential to do more harm. However, it is still a judgement and it is possible that some pathologists might still label your lesion severely atypical. It has been thought that pathologists might over-diagnose melanoma just to be on the safe side (CYA).
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- December 28, 2016 at 7:21 pm
It's a matter of degrees. The is just more cellular atypia or architectural atypia in melanoma in situ than a dysplastic mole. They look at a lot of factors and at some point, it crosses the line to a lesion that has the potential to do more harm. However, it is still a judgement and it is possible that some pathologists might still label your lesion severely atypical. It has been thought that pathologists might over-diagnose melanoma just to be on the safe side (CYA).
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- December 28, 2016 at 7:21 pm
It's a matter of degrees. The is just more cellular atypia or architectural atypia in melanoma in situ than a dysplastic mole. They look at a lot of factors and at some point, it crosses the line to a lesion that has the potential to do more harm. However, it is still a judgement and it is possible that some pathologists might still label your lesion severely atypical. It has been thought that pathologists might over-diagnose melanoma just to be on the safe side (CYA).
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- January 1, 2017 at 12:41 am
The difference between an atypical mole vs melanoma is based on the observed degree of change. The atypical mole will show cells that are not exactly normal but still resemble normal mature melanocytes. The cells of an insitu will look much more primitive and often contain large and irregular nuclei. The process of becoming malignant is called anaplasia- the transformation to a more primitive malignant state. You can look up the terms differentation, anaplasia, and mitosis if you want some technical information on how a pathologist determines whether a lesion is atypical or malignant. There are other factors but these will give you the basics. You may also want to learn more about the epidermis and dermis and the junction between the two. The main thing to know is that if you were to have a melonoma you are fortunate that it was insitu. Your pathologist saw enough abnormality in those cells to warrant the dx. Be happy it was caught early and don't doubt his judgement. He or she looks and many many tissue samples and knows exactly what they are looking for.
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- January 1, 2017 at 12:41 am
The difference between an atypical mole vs melanoma is based on the observed degree of change. The atypical mole will show cells that are not exactly normal but still resemble normal mature melanocytes. The cells of an insitu will look much more primitive and often contain large and irregular nuclei. The process of becoming malignant is called anaplasia- the transformation to a more primitive malignant state. You can look up the terms differentation, anaplasia, and mitosis if you want some technical information on how a pathologist determines whether a lesion is atypical or malignant. There are other factors but these will give you the basics. You may also want to learn more about the epidermis and dermis and the junction between the two. The main thing to know is that if you were to have a melonoma you are fortunate that it was insitu. Your pathologist saw enough abnormality in those cells to warrant the dx. Be happy it was caught early and don't doubt his judgement. He or she looks and many many tissue samples and knows exactly what they are looking for.
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- January 1, 2017 at 12:41 am
The difference between an atypical mole vs melanoma is based on the observed degree of change. The atypical mole will show cells that are not exactly normal but still resemble normal mature melanocytes. The cells of an insitu will look much more primitive and often contain large and irregular nuclei. The process of becoming malignant is called anaplasia- the transformation to a more primitive malignant state. You can look up the terms differentation, anaplasia, and mitosis if you want some technical information on how a pathologist determines whether a lesion is atypical or malignant. There are other factors but these will give you the basics. You may also want to learn more about the epidermis and dermis and the junction between the two. The main thing to know is that if you were to have a melonoma you are fortunate that it was insitu. Your pathologist saw enough abnormality in those cells to warrant the dx. Be happy it was caught early and don't doubt his judgement. He or she looks and many many tissue samples and knows exactly what they are looking for.
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Tagged: cutaneous melanoma
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