MRF-Logo2019-Horizontal-RGB
Oncologists want PD-1 as first line treatment
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

Oncologists want PD-1 as first line treatment

› Forums › General Melanoma Community › Oncologists want PD-1 as first line treatment

  • This topic is empty.
  • Post
    • August 7, 2014 at 9:44 pm
    Scuba Doc
    Participant

       

      Insight, Analysis & Opinion

      Discerning the importance of Merck's pembrolizumab likely becoming the first PD-1 therapy to reach the market in the US is challenging. From a sentiment perspective, a confirmed PDUFA date for October 28 has helped to drive conviction among Merck's investors that the company has gained ground on Bristol-Myers Squibb, which 12 months ago appeared to have a more discernible lead in this particular race.

      From a commercial perspective, the data generated for pembrolizumab suggests that once approval for Yervoy-refractory (i.e. second-line) melanoma occurs, there will be earlier usage of the product in the treatment paradigm. Indeed, when FirstWord polled 70 US-based oncologists after the ASCO annual meeting in May, they suggested that based on currently-available data they would prescribe pembrolizumab to around a third of first-line patients in an off-label capacity – a trend that could be enhanced if Merck's drug also receives NCCN guideline support.

    • You must be logged in to reply to this topic.
    About the MRF Patient Forum

    The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

    The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

    Popular Topics