So I think that some numbness and weakness in hands and feet is pretty common with both nivo and ipi. Wondering if anyone – other than myself – has had it go beyond that to significant pain? Up until a few weeks ago, my melanoma hadn’t had any substantial impact on my physical abilities. I started to notice a little numbness in the feet, and then almost overnight, it exploded into severe pain in the legs, mostly in the calf muscles on both legs, along with numbness in the feet. It was like having a charley horse in both calves, but it never went away. Especially bad at night, which caused me to go 4-5 nights with truly almost zero sleep. Finally had to call the doctor, and they initially gave me some pain killer that did nothing, and then a combo of oxycodone, gabapentin and steroids, which eventually got it under control. Eventually the pain in the muscles went away, but now it has moved just to the feet and toes. Still very painful, but not quite as bad. Only doing the gabapentin and over the counter to control the pain. Kind of shuffling around now. Anyway, still haven’t identified a cause, be it adverse reaction to treatments or spread of mel somewhere or something else. Just wondering if anyone else has had something similar.
By the way, I mentioned in another post that I had a gamma knife recently. They specifically said that they didn’t believe the two were related, because the area of the brain where I had the gamma knife has nothing to do with my legs. They said it was near and area involved in vision.
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