Mucosal melanoma – Yervoy response

I just took my 2nd dose of yervoy 7 days ago. They told me I would see no side affects on the 1st dose and I might start seeing them on the 2nd. They also said Yervoy takes quite awhile to work. Even months they said. They also said if I start seeing side affects that is a good thing because it means it is working. They also said they see the best results with people who have the most side affects. The dr/nurse telling me this have been doing yervoy way back when it was in trials so I believe them. I had no side affects with the 1st dose. So far all I've had was the night of the 2nd dose I was very dizzy. Also several short hour long stomach churnings that come and go. I have no idea about high dose IL-2. I know yervoy and nivolumab work in similar ways and are supposed to be good for the long term success but they take a long time to work.

I just took my 2nd dose of yervoy 7 days ago. They told me I would see no side affects on the 1st dose and I might start seeing them on the 2nd. They also said Yervoy takes quite awhile to work. Even months they said. They also said if I start seeing side affects that is a good thing because it means it is working. They also said they see the best results with people who have the most side affects. The dr/nurse telling me this have been doing yervoy way back when it was in trials so I believe them. I had no side affects with the 1st dose. So far all I've had was the night of the 2nd dose I was very dizzy. Also several short hour long stomach churnings that come and go. I have no idea about high dose IL-2. I know yervoy and nivolumab work in similar ways and are supposed to be good for the long term success but they take a long time to work.

I just took my 2nd dose of yervoy 7 days ago. They told me I would see no side affects on the 1st dose and I might start seeing them on the 2nd. They also said Yervoy takes quite awhile to work. Even months they said. They also said if I start seeing side affects that is a good thing because it means it is working. They also said they see the best results with people who have the most side affects. The dr/nurse telling me this have been doing yervoy way back when it was in trials so I believe them. I had no side affects with the 1st dose. So far all I've had was the night of the 2nd dose I was very dizzy. Also several short hour long stomach churnings that come and go. I have no idea about high dose IL-2. I know yervoy and nivolumab work in similar ways and are supposed to be good for the long term success but they take a long time to work.

If you are in good enough physical shape, Mentally, heart and lungs fair IL-2 should be an option.  If you go to it you want to do it at a location that is well experiencedd with hndling the side effects.  It can bae roug, but you know shortly if you area responding, and are unlikely to have any long term negative side effects.  I had 49 bags spread over 20 months of si,x 6 day administration periods in a special IL-2 ward.  The IL-2 extended my life with a good quality for those 20 months, before my stable mets once more became fast growing and innumerabale new mets arouse.  A new development had arisen and I have continued essentil stable on Gleevec  for another 5 years so far.

      There have been three follow-on targeted drugs test being used now on GIST, which is anothe cancer that is quite likely to have a C-kit mutation.

SUTENT:  SUTENT is used when the medicine Gleevec® (imatinib mesylate) did not stop the cancer from growing or when you cannot take Gleevec.

Tyrosine kinase inhibitors (TKI) are used for the treatment of various cancers. Case reports and clinical trials have reported abnormal thyroid function tests (TFT) after treatment with sunitinib, imatinib, sorafenib, dasatinib, and nilotinib. An increased requirement for levothyroxine was reported in thyroidectomized patients during TKI treatment.

Good luck.

If you are in good enough physical shape, Mentally, heart and lungs fair IL-2 should be an option.  If you go to it you want to do it at a location that is well experiencedd with hndling the side effects.  It can bae roug, but you know shortly if you area responding, and are unlikely to have any long term negative side effects.  I had 49 bags spread over 20 months of si,x 6 day administration periods in a special IL-2 ward.  The IL-2 extended my life with a good quality for those 20 months, before my stable mets once more became fast growing and innumerabale new mets arouse.  A new development had arisen and I have continued essentil stable on Gleevec  for another 5 years so far.

      There have been three follow-on targeted drugs test being used now on GIST, which is anothe cancer that is quite likely to have a C-kit mutation.

SUTENT:  SUTENT is used when the medicine Gleevec® (imatinib mesylate) did not stop the cancer from growing or when you cannot take Gleevec.

Tyrosine kinase inhibitors (TKI) are used for the treatment of various cancers. Case reports and clinical trials have reported abnormal thyroid function tests (TFT) after treatment with sunitinib, imatinib, sorafenib, dasatinib, and nilotinib. An increased requirement for levothyroxine was reported in thyroidectomized patients during TKI treatment.

Good luck.

If you are in good enough physical shape, Mentally, heart and lungs fair IL-2 should be an option.  If you go to it you want to do it at a location that is well experiencedd with hndling the side effects.  It can bae roug, but you know shortly if you area responding, and are unlikely to have any long term negative side effects.  I had 49 bags spread over 20 months of si,x 6 day administration periods in a special IL-2 ward.  The IL-2 extended my life with a good quality for those 20 months, before my stable mets once more became fast growing and innumerabale new mets arouse.  A new development had arisen and I have continued essentil stable on Gleevec  for another 5 years so far.

      There have been three follow-on targeted drugs test being used now on GIST, which is anothe cancer that is quite likely to have a C-kit mutation.

SUTENT:  SUTENT is used when the medicine Gleevec® (imatinib mesylate) did not stop the cancer from growing or when you cannot take Gleevec.

Tyrosine kinase inhibitors (TKI) are used for the treatment of various cancers. Case reports and clinical trials have reported abnormal thyroid function tests (TFT) after treatment with sunitinib, imatinib, sorafenib, dasatinib, and nilotinib. An increased requirement for levothyroxine was reported in thyroidectomized patients during TKI treatment.

Good luck.