MRF-Logo2019-Horizontal-RGB
mucosal melanoma wild type mutation
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

mucosal melanoma wild type mutation

› Forums › Mucosal Melanoma Community › mucosal melanoma wild type mutation

  • Post
    • April 7, 2014 at 8:26 pm
    mary1233
    Participant

      Can anyone answer this for me. I know that mucosal melanoma is rare. How rare is the BRAF wild type mutation?

       

      Thanks.

       

    Viewing 2 reply threads
    • Replies
        • April 7, 2014 at 10:03 pm
        Janner
        Participant

          "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

            • April 8, 2014 at 12:38 pm
            Phil S
            Participant

              Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

              • April 8, 2014 at 12:38 pm
              Phil S
              Participant

                Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

                • April 8, 2014 at 12:38 pm
                Phil S
                Participant

                  Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

                  • April 8, 2014 at 1:01 pm
                  mary1233
                  Participant

                    All cancers have mutations – wild type is mutations that have not been identified.

                    • April 8, 2014 at 1:01 pm
                    mary1233
                    Participant

                      All cancers have mutations – wild type is mutations that have not been identified.

                      • April 8, 2014 at 1:01 pm
                      mary1233
                      Participant

                        All cancers have mutations – wild type is mutations that have not been identified.

                      • April 7, 2014 at 10:03 pm
                      Janner
                      Participant

                        "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

                        • April 7, 2014 at 10:03 pm
                        Janner
                        Participant

                          "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

                      Viewing 2 reply threads

                      Tagged: 

                      • You must be logged in to reply to this topic.
                      About the MRF Patient Forum

                      The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                      The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                      Popular Topics