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mucosal melanoma wild type mutation

Forums Mucosal Melanoma Community mucosal melanoma wild type mutation

  • Post
    mary1233
    Participant

      Can anyone answer this for me. I know that mucosal melanoma is rare. How rare is the BRAF wild type mutation?

       

      Thanks.

       

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    • Replies
        Janner
        Participant

          "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

            Phil S
            Participant

              Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

              Phil S
              Participant

                Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

                Phil S
                Participant

                  Mucosal melanoma will not have the BRAF mutation, it may have the CKit mutation, so get tested!  My husband has mucosal melanoma and has neither Braf or CKit mutations.  So, he is considered wild type!    Valerie (Phil's wife)

                  mary1233
                  Participant

                    All cancers have mutations – wild type is mutations that have not been identified.

                    mary1233
                    Participant

                      All cancers have mutations – wild type is mutations that have not been identified.

                      mary1233
                      Participant

                        All cancers have mutations – wild type is mutations that have not been identified.

                      Janner
                      Participant

                        "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

                        Janner
                        Participant

                          "Wild Type" means normal – no mutation.  So wild type BRAF will not respond to any of the BRAF related drugs.  Last I heard, BRAF mutations occur in somewhere around 50% of melanomas so wild type is probably the other 50%.

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