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MK-3475 Approval?
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MK-3475 Approval?

› Forums › General Melanoma Community › MK-3475 Approval?

  • Post
    • June 23, 2014 at 1:05 pm
    Scuba Doc
    Participant

      Rumor from a reliable source says MK-3475 (pembrolizumab) could be approved as early as mid summer. 

    Viewing 2 reply threads
    • Replies
        • June 23, 2014 at 2:01 pm
        rosa1
        Participant

          Does this source also mention any restrictions, such as prior IPI fail and/or BRAF therapies if BRAF positive?

          • June 23, 2014 at 2:01 pm
          rosa1
          Participant

            Does this source also mention any restrictions, such as prior IPI fail and/or BRAF therapies if BRAF positive?

              • June 23, 2014 at 2:27 pm
              Scuba Doc
              Participant

                He did not give any more info. — but I research those  questions daily — I hope the individual oncologist can make that decision.

                • June 23, 2014 at 2:27 pm
                Scuba Doc
                Participant

                  He did not give any more info. — but I research those  questions daily — I hope the individual oncologist can make that decision.

                  • June 23, 2014 at 2:27 pm
                  Scuba Doc
                  Participant

                    He did not give any more info. — but I research those  questions daily — I hope the individual oncologist can make that decision.

                    • June 23, 2014 at 2:49 pm
                    RJoeyB
                    Participant

                      Catherine Poole at MIF has been trying to gather information from her contacts about this and put up a post this morning with some information here:

                      http://forum.melanomainternational.org/mif/viewtopic.php?f=54&t=35124

                       

                      • June 23, 2014 at 4:20 pm
                      Scuba Doc
                      Participant

                        On a more favorable note — When looking at this report, it looks like patients who are  IPI untreated do better that IPI treated patients when given pembrolizumab —– 

                        http://www.businesswire.com/news/home/20140602005550/en/Data-Merck%E2%80%99s-Pembrolizumab-Largest-Study-Date-Investigational#.U6hSSZt15w5

                        • June 23, 2014 at 5:50 pm
                        KatB
                        Participant

                          Favorable for some, I suppose…

                          • June 23, 2014 at 5:50 pm
                          KatB
                          Participant

                            Favorable for some, I suppose…

                            • June 23, 2014 at 5:50 pm
                            KatB
                            Participant

                              Favorable for some, I suppose…

                              • June 24, 2014 at 8:50 pm
                              Cooper
                              Participant

                                How is that favorable if they require you to have IPI before you can get PD1!

                                • June 24, 2014 at 8:50 pm
                                Cooper
                                Participant

                                  How is that favorable if they require you to have IPI before you can get PD1!

                                  • June 25, 2014 at 11:26 am
                                  Scuba Doc
                                  Participant

                                    Perhaps with all the new test results Merck will allow melanoma patients to take pembrolizumab regardless of having been previously treated with IPI. I know that some patients opted not to take the IPI for other health reasons. Allowing those patients access to pembrolizumab seem like a no brainer based on the current data.

                                    • June 25, 2014 at 11:26 am
                                    Scuba Doc
                                    Participant

                                      Perhaps with all the new test results Merck will allow melanoma patients to take pembrolizumab regardless of having been previously treated with IPI. I know that some patients opted not to take the IPI for other health reasons. Allowing those patients access to pembrolizumab seem like a no brainer based on the current data.

                                      • June 25, 2014 at 5:36 pm
                                      Cooper
                                      Participant

                                        It is up to the FDA to decide, be sure to write or call them or your congressman

                                        • June 25, 2014 at 5:36 pm
                                        Cooper
                                        Participant

                                          It is up to the FDA to decide, be sure to write or call them or your congressman

                                          • June 25, 2014 at 5:36 pm
                                          Cooper
                                          Participant

                                            It is up to the FDA to decide, be sure to write or call them or your congressman

                                            • June 25, 2014 at 11:26 am
                                            Scuba Doc
                                            Participant

                                              Perhaps with all the new test results Merck will allow melanoma patients to take pembrolizumab regardless of having been previously treated with IPI. I know that some patients opted not to take the IPI for other health reasons. Allowing those patients access to pembrolizumab seem like a no brainer based on the current data.

                                              • June 24, 2014 at 8:50 pm
                                              Cooper
                                              Participant

                                                How is that favorable if they require you to have IPI before you can get PD1!

                                                • June 23, 2014 at 4:20 pm
                                                Scuba Doc
                                                Participant

                                                  On a more favorable note — When looking at this report, it looks like patients who are  IPI untreated do better that IPI treated patients when given pembrolizumab —– 

                                                  http://www.businesswire.com/news/home/20140602005550/en/Data-Merck%E2%80%99s-Pembrolizumab-Largest-Study-Date-Investigational#.U6hSSZt15w5

                                                  • June 23, 2014 at 4:20 pm
                                                  Scuba Doc
                                                  Participant

                                                    On a more favorable note — When looking at this report, it looks like patients who are  IPI untreated do better that IPI treated patients when given pembrolizumab —– 

                                                    http://www.businesswire.com/news/home/20140602005550/en/Data-Merck%E2%80%99s-Pembrolizumab-Largest-Study-Date-Investigational#.U6hSSZt15w5

                                                    • June 23, 2014 at 2:49 pm
                                                    RJoeyB
                                                    Participant

                                                      Catherine Poole at MIF has been trying to gather information from her contacts about this and put up a post this morning with some information here:

                                                      http://forum.melanomainternational.org/mif/viewtopic.php?f=54&t=35124

                                                       

                                                      • June 23, 2014 at 2:49 pm
                                                      RJoeyB
                                                      Participant

                                                        Catherine Poole at MIF has been trying to gather information from her contacts about this and put up a post this morning with some information here:

                                                        http://forum.melanomainternational.org/mif/viewtopic.php?f=54&t=35124

                                                         

                                                      • June 23, 2014 at 2:01 pm
                                                      rosa1
                                                      Participant

                                                        Does this source also mention any restrictions, such as prior IPI fail and/or BRAF therapies if BRAF positive?

                                                    Viewing 2 reply threads
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