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Mixed results for TIL – Back to the drawing board
›Forums›Mixed results for TIL – Back to the drawing board
Rose got through her TIL trial at SCCA bravely, and saw complete and rapid reduction in her head, neck and lung tumors. Unfortunately, the 42 day scans showed major progression in the liver. Very puzzling for the trial team. We have been referred back to our on oncologist for next steps.
Anyone have similar mixed response with TIL? Thoughts on what next?. Pretty sure she will go back on braf/mek in short term.
We are scared and concerned about running out of options.
Glad to hear of rapid tumor reduction in some areas and that Rose is, unsurprisingly, one tough cookie! Unfortunately, melanoma liver lesions are known to be persistent and difficult. I’ve posted various reports to that effect. However, there are reports in the literature and anecdotally shared by melanoma patients that radiation can be very helpful.
Thank you Celeste. She has extensive lesions in the liver so don’t know if radiation is in order but will address in our consults with both SCCA and cc next week. She was responsive to a short dose of braf mek, hopeful that if she goes back on it the liver will respond…need to do more research on that. Needless to say we are disappointed and scared…the TIL trial was brutal and we were not prepared for bad news.
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