› Forums › General Melanoma Community › Major rash.. Trial of Opdivo and epacadostat
- This topic has 6 replies, 2 voices, and was last updated 7 years, 9 months ago by jade1111.
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- July 20, 2016 at 5:34 pm
Hello.. My mom had her first infusion 11 days ago. She felt fine till around day 9.. had some severe cant move nausea (seems to have lifted as she is holding on pills) and bad fatigue and a very angry looking rash on her legs and arms. She is using a topical steroid and claritin. She is currently in a trial.. not sure if she will be able to get infusion tomorrow.. hard to think of her doing that with such a bad rash… and not sure what will happen if she does not get infusion..will she be out of trail.. the trial is good but its complicated feel this time pressure.. though I know they have her safety first.. just so much testing to get into trial.. Venting… Anyway any thoughts on rashes… how long they lasted and doing an infusion with one? Just read in previous post about taking anithistamine at time of infusion.. wonder if she takes consitently would help.
Thanks!!!
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- July 20, 2016 at 11:12 pm
Hi Jade, each trial is set up a little different than the next but one thing that should be similiar is how they assess the grade of the adverse reaction. The Oncologist will have a set of criteria to follow, some times they have to skip a treatment and wait for side effects from the drug to resolve. Each case is different but the guidelines are the same. They grade the side effects 1 to 4 and for each level there is a set of criteria to follow. If you look up the drug on the internet you can usuall find the guidelines. I hope things go well tomorrow, best wishes!!!Ed
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- July 20, 2016 at 11:12 pm
Hi Jade, each trial is set up a little different than the next but one thing that should be similiar is how they assess the grade of the adverse reaction. The Oncologist will have a set of criteria to follow, some times they have to skip a treatment and wait for side effects from the drug to resolve. Each case is different but the guidelines are the same. They grade the side effects 1 to 4 and for each level there is a set of criteria to follow. If you look up the drug on the internet you can usuall find the guidelines. I hope things go well tomorrow, best wishes!!!Ed
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- July 20, 2016 at 11:12 pm
Hi Jade, each trial is set up a little different than the next but one thing that should be similiar is how they assess the grade of the adverse reaction. The Oncologist will have a set of criteria to follow, some times they have to skip a treatment and wait for side effects from the drug to resolve. Each case is different but the guidelines are the same. They grade the side effects 1 to 4 and for each level there is a set of criteria to follow. If you look up the drug on the internet you can usuall find the guidelines. I hope things go well tomorrow, best wishes!!!Ed
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