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Lytic lesions on spine and pelvis after ipi

Forums General Melanoma Community Lytic lesions on spine and pelvis after ipi

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    justlittleoleme
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      My husbands scans on Feb. 24th have shown 2 lytic lesions on T8, T9 & T10 and 1 lytic lesion on his right pelvis.  He underwent a needle biopsy while in the hospital for ipi induced hepatoxicity.  It confirmed they were metastatic melanoma.

      My husbands scans on Feb. 24th have shown 2 lytic lesions on T8, T9 & T10 and 1 lytic lesion on his right pelvis.  He underwent a needle biopsy while in the hospital for ipi induced hepatoxicity.  It confirmed they were metastatic melanoma.

      He is currently on mega doses of methylprednisolone.  We are getting repeat scans on April 9th to see if we see evidence of shrinkage or growth.  At that time he will be 8 weeks post ipi induction phase.  He is currently off study due to his side effects.  His oncologist has ruled out any immunological treatments at this time due to the severity of the ipi side effects.

      She is currently talking about doing a bone strengthening treatment, Zometa at his appointment on the 9th.  She is looking at Temodar as his next treatment.  I am concerned about Temodar since it may have a limited life and he currently has no brain involvement.

      Any thoughts or suggestions?

      barb

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