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Keytruda Side Effect
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Keytruda Side Effect

› Forums › General Melanoma Community › Keytruda Side Effect

  • Post
    • November 17, 2015 at 3:50 am
    Squash
    Participant

      I have had four infusions of keytruda without really any side effects.

      However in the last couple of days i have been having the urge to go to the toilet badly and only a bit comes out and my bottom or sphincer is really sore. I mean it is really sore after defecating.

      In fact it is dangerous for me to pass wind as i might soil myself a bit..

      I know i could use immodium but the thting is I am not really constipated in fact it seems i only get a bit out but i still have the urge to go to the toilet. I dont see my doctor for another week.

      Has anyone else had similar symptoms and what have you done? 

       

    Viewing 8 reply threads
    • Replies
        • November 17, 2015 at 12:54 pm
        arthurjedi007
        Participant

          Preparation h wipes and spraying with witch hazel might help the soreness. If you are able walk a couple miles a day to keep the plumbing good. Make sure you eat enough fiber like from bread. Even before melanoma I've had that issue but it usually only lasted a few days to a week and I could always trace it back to something I ate like Taco Bell or something. Might be keytruda who knows.

          Artie

          • November 17, 2015 at 12:54 pm
          arthurjedi007
          Participant

            Preparation h wipes and spraying with witch hazel might help the soreness. If you are able walk a couple miles a day to keep the plumbing good. Make sure you eat enough fiber like from bread. Even before melanoma I've had that issue but it usually only lasted a few days to a week and I could always trace it back to something I ate like Taco Bell or something. Might be keytruda who knows.

            Artie

            • November 17, 2015 at 12:54 pm
            arthurjedi007
            Participant

              Preparation h wipes and spraying with witch hazel might help the soreness. If you are able walk a couple miles a day to keep the plumbing good. Make sure you eat enough fiber like from bread. Even before melanoma I've had that issue but it usually only lasted a few days to a week and I could always trace it back to something I ate like Taco Bell or something. Might be keytruda who knows.

              Artie

                • November 17, 2015 at 2:03 pm
                Squash
                Participant

                  Thanks Artie

                  I didnt have this problem ever before.

                  I just seem to have a lot of gas but am not getting a bowel movement with it and all i get is a litte trickle and it is getting really sore.

                   

                  • November 17, 2015 at 4:11 pm
                  Julie in SoCal
                  Participant

                    Hi Anon,

                    I just finished my 10th infusion of Keytruda, and I usually have a bit of "urgency" and gas the first week after the infusion. But then it goes away.  My Dr has said that if I have further troubles to give him a call.  

                    I would definitely talk with your dr about it.  

                    Blessings,

                    Julie

                    • November 17, 2015 at 4:11 pm
                    Julie in SoCal
                    Participant

                      Hi Anon,

                      I just finished my 10th infusion of Keytruda, and I usually have a bit of "urgency" and gas the first week after the infusion. But then it goes away.  My Dr has said that if I have further troubles to give him a call.  

                      I would definitely talk with your dr about it.  

                      Blessings,

                      Julie

                      • November 17, 2015 at 4:11 pm
                      Julie in SoCal
                      Participant

                        Hi Anon,

                        I just finished my 10th infusion of Keytruda, and I usually have a bit of "urgency" and gas the first week after the infusion. But then it goes away.  My Dr has said that if I have further troubles to give him a call.  

                        I would definitely talk with your dr about it.  

                        Blessings,

                        Julie

                        • November 17, 2015 at 6:02 pm
                        arthurjedi007
                        Participant

                          Maybe try some mineral oil or mirilax to soften the bowels so you get more than a trickle.

                          I do the wipes and witch hazel all the time cause of my hemroids. Otherwise would be sore. Cause of the pain meds I now have to do the mirilax .

                          Artie

                          • November 17, 2015 at 6:02 pm
                          arthurjedi007
                          Participant

                            Maybe try some mineral oil or mirilax to soften the bowels so you get more than a trickle.

                            I do the wipes and witch hazel all the time cause of my hemroids. Otherwise would be sore. Cause of the pain meds I now have to do the mirilax .

                            Artie

                            • November 17, 2015 at 6:02 pm
                            arthurjedi007
                            Participant

                              Maybe try some mineral oil or mirilax to soften the bowels so you get more than a trickle.

                              I do the wipes and witch hazel all the time cause of my hemroids. Otherwise would be sore. Cause of the pain meds I now have to do the mirilax .

                              Artie

                              • November 17, 2015 at 2:03 pm
                              Squash
                              Participant

                                Thanks Artie

                                I didnt have this problem ever before.

                                I just seem to have a lot of gas but am not getting a bowel movement with it and all i get is a litte trickle and it is getting really sore.

                                 

                                • November 17, 2015 at 2:03 pm
                                Squash
                                Participant

                                  Thanks Artie

                                  I didnt have this problem ever before.

                                  I just seem to have a lot of gas but am not getting a bowel movement with it and all i get is a litte trickle and it is getting really sore.

                                   

                                • November 18, 2015 at 6:47 am
                                MattF
                                Participant

                                  hey

                                  19th Keytruda here and I have no rectum soreness,,,,but gas since day one….

                                   

                                  sometimes its a gas day and sometimes a poop day. 

                                  i started full dose of laxitives and a full dose of stool softners everyday….and tried to eat normal healthy

                                  i regulated out to 1 or 2 trips to bathroom pewr day for bowel movement

                                  • November 18, 2015 at 6:47 am
                                  MattF
                                  Participant

                                    hey

                                    19th Keytruda here and I have no rectum soreness,,,,but gas since day one….

                                     

                                    sometimes its a gas day and sometimes a poop day. 

                                    i started full dose of laxitives and a full dose of stool softners everyday….and tried to eat normal healthy

                                    i regulated out to 1 or 2 trips to bathroom pewr day for bowel movement

                                    • November 18, 2015 at 6:47 am
                                    MattF
                                    Participant

                                      hey

                                      19th Keytruda here and I have no rectum soreness,,,,but gas since day one….

                                       

                                      sometimes its a gas day and sometimes a poop day. 

                                      i started full dose of laxitives and a full dose of stool softners everyday….and tried to eat normal healthy

                                      i regulated out to 1 or 2 trips to bathroom pewr day for bowel movement

                                      • November 20, 2015 at 4:37 am
                                      Beehappy
                                      Participant

                                        My husband is on the ipi vs. nivo study.  We are not sure which of the drugs he has been given, but he started having this problem as well a month into treatment.  He tried over the counter pads and cream for relief but found coconut oil to be the best topical relief. 

                                        Rebecca

                                        • November 20, 2015 at 4:37 am
                                        Beehappy
                                        Participant

                                          My husband is on the ipi vs. nivo study.  We are not sure which of the drugs he has been given, but he started having this problem as well a month into treatment.  He tried over the counter pads and cream for relief but found coconut oil to be the best topical relief. 

                                          Rebecca

                                            • November 22, 2015 at 1:38 am
                                            Squash
                                            Participant

                                              I am using coconut oil too.

                                              I wonder thou how long this problem is going to go on.

                                              I am taking gastro stop every four hours for a week now with no end in sight.

                                              How can i get some resolution?

                                               

                                              • November 22, 2015 at 1:38 am
                                              Squash
                                              Participant

                                                I am using coconut oil too.

                                                I wonder thou how long this problem is going to go on.

                                                I am taking gastro stop every four hours for a week now with no end in sight.

                                                How can i get some resolution?

                                                 

                                                • November 22, 2015 at 1:38 am
                                                Squash
                                                Participant

                                                  I am using coconut oil too.

                                                  I wonder thou how long this problem is going to go on.

                                                  I am taking gastro stop every four hours for a week now with no end in sight.

                                                  How can i get some resolution?

                                                   

                                                • November 20, 2015 at 4:37 am
                                                Beehappy
                                                Participant

                                                  My husband is on the ipi vs. nivo study.  We are not sure which of the drugs he has been given, but he started having this problem as well a month into treatment.  He tried over the counter pads and cream for relief but found coconut oil to be the best topical relief. 

                                                  Rebecca

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