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Keytruda/fatigue and Provigil (modafinil) tweak
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Keytruda/fatigue and Provigil (modafinil) tweak

› Forums › General Melanoma Community › Keytruda/fatigue and Provigil (modafinil) tweak

  • Post
    • September 23, 2015 at 11:19 pm
    AnitaLoree
    Participant

      Thx Paul for posting yesterday re your Keytruda fatigue, taking a break, now trying modafinil with good results.  Fatigue from Keytruda bugs my husband too so spoke w our oncologist @ today's exam/infusion. He says the latest is a tweaked form: Nuvigil (armadafinil), apparently less SE's/interactions.  Is being used in several glioblastoma trials bcs fatigue such a big problem for glioblastoma folks. (Didn't get into if Kaiser is involved in any). We will pursue this next month. Husband's celebrating 1 yr anniversary on Keytruda and continues PFS. So grateful for this extra time and don't want to mess anything up! Will tread carefully but would be great to have some energy again. Peace, perseverence and +++++mindset to all you tough mel warriors. A.L.

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        • September 24, 2015 at 3:10 pm
        _Paul_
        Participant

          You are very welcome Anita Loree!

          I have been on it for a week now, and I am tolerating it well. Adjusting the dosage was important for me. Too much and I would feel anxious. Too little and I would feel tired. Right now taking 100mg when I wake up seems to do the trick, but about 12 hours later I am back to sleepy. But that's ok, since my day is pretty much over by then.

          I hope he finds the best solution to his fatigue. And congratulations on one year! I just had mine and it was a big deal to me, it meant I had made it past my expiration date. Very happy for you two!

          – Paul

          • September 24, 2015 at 3:10 pm
          _Paul_
          Participant

            You are very welcome Anita Loree!

            I have been on it for a week now, and I am tolerating it well. Adjusting the dosage was important for me. Too much and I would feel anxious. Too little and I would feel tired. Right now taking 100mg when I wake up seems to do the trick, but about 12 hours later I am back to sleepy. But that's ok, since my day is pretty much over by then.

            I hope he finds the best solution to his fatigue. And congratulations on one year! I just had mine and it was a big deal to me, it meant I had made it past my expiration date. Very happy for you two!

            – Paul

            • September 24, 2015 at 3:10 pm
            _Paul_
            Participant

              You are very welcome Anita Loree!

              I have been on it for a week now, and I am tolerating it well. Adjusting the dosage was important for me. Too much and I would feel anxious. Too little and I would feel tired. Right now taking 100mg when I wake up seems to do the trick, but about 12 hours later I am back to sleepy. But that's ok, since my day is pretty much over by then.

              I hope he finds the best solution to his fatigue. And congratulations on one year! I just had mine and it was a big deal to me, it meant I had made it past my expiration date. Very happy for you two!

              – Paul

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