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Just a piece of advice…

Forums General Melanoma Community Just a piece of advice…

  • Post
    jualonso
    Participant

      Hi folks,

      Some of you know that few days ago i failed on BRAF inh. And now im on the decision way.  A new meat appeared in my lung, a very small one SUV 5.1 but all others, including my armpit nodule, are not in PET. As far as i know, a new met always means progression, so i have to change the treatment. My onc. Wanted to stop pills but finallywe decided to continue, at least till i decide what to do. IPI is the most clear option but new Trials are going to come out in a little time in Spain and i want to see if something more interesting could be on them. May be a Combo pembro and ipi or something like that. Now my Onc. Wants to wait 1.5 month to see everything with more perpective. But as you know after Fail Braf the tumor could become more agressive and everyday counts. I want to wait just 15 max for trials information and start IPI inmediatly. Well, thanks for your pieces of advice in this difficult moment.

       

      Juan

       

       

       

       

       

       

    Viewing 5 reply threads
    • Replies
        Tim–MRF
        Guest

          Juan:

          I am sorry to hear about the new tumor. I am not sure I have a lot of advice, and you clearly are well informed about the treatment landscape. I do have a couple of thoughts. The ipi/ nivolumab combination is very intriguing, though it has a lot of side effects. The response rates are very impressinve.

          If you do decide to take ipi as monotherapy it opens the door for future use of pembro (Merck's anti-PD!). In the United States pembro was just approved, but you  must have had ipi first before you can take it. I don't how this will be viewed in Spain.

          Tim–MRF

           

          Tim–MRF
          Guest

            Juan:

            I am sorry to hear about the new tumor. I am not sure I have a lot of advice, and you clearly are well informed about the treatment landscape. I do have a couple of thoughts. The ipi/ nivolumab combination is very intriguing, though it has a lot of side effects. The response rates are very impressinve.

            If you do decide to take ipi as monotherapy it opens the door for future use of pembro (Merck's anti-PD!). In the United States pembro was just approved, but you  must have had ipi first before you can take it. I don't how this will be viewed in Spain.

            Tim–MRF

             

            Tim–MRF
            Guest

              Juan:

              I am sorry to hear about the new tumor. I am not sure I have a lot of advice, and you clearly are well informed about the treatment landscape. I do have a couple of thoughts. The ipi/ nivolumab combination is very intriguing, though it has a lot of side effects. The response rates are very impressinve.

              If you do decide to take ipi as monotherapy it opens the door for future use of pembro (Merck's anti-PD!). In the United States pembro was just approved, but you  must have had ipi first before you can take it. I don't how this will be viewed in Spain.

              Tim–MRF

               

              BrianP
              Participant

                Juan,

                I don't have any advice for you either.  I think if I were in your shoes my line of thinking would be pretty similar to your's.  I wish you the best and hope you have a little luck on your side with the combo trials.

                Brian

                BrianP
                Participant

                  Juan,

                  I don't have any advice for you either.  I think if I were in your shoes my line of thinking would be pretty similar to your's.  I wish you the best and hope you have a little luck on your side with the combo trials.

                  Brian

                  BrianP
                  Participant

                    Juan,

                    I don't have any advice for you either.  I think if I were in your shoes my line of thinking would be pretty similar to your's.  I wish you the best and hope you have a little luck on your side with the combo trials.

                    Brian

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