MRF-Logo2019-Horizontal-RGB
INTERLEUKIN-12
REGISTER
The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Content within the patient forum is user-generated and has not been reviewed by medical professionals. Other sections of the Melanoma Research Foundation website include information that has been reviewed by medical professionals as appropriate. All medical decisions should be made in consultation with your doctor or other qualified medical professional.

INTERLEUKIN-12

› Forums › General Melanoma Community › INTERLEUKIN-12

  • Post
    • October 6, 2015 at 12:11 pm
    Daisyduke
    Participant

      Hi,

       

      Has anyone used this drug and what have you heard about this treatment?  I am going to see a Doctor who has tried this vaccine on patients and I don't know much about it.  

      I believe this is an alternative option for Stage III Melanoma.

       

      Thanks for any input.

       

    Viewing 8 reply threads
    • Replies
        • October 6, 2015 at 4:24 pm
        geriakt
        Participant

          Interluken 2 is not a vaccine. It is an older drug to boost your immune functions. It is very similar to Interferon. 

          Do your research and read up about it as there will be many side effect when on it and you may feel like you have a bad case of the flu.

           

          I wish you the best

          Tom

            • October 6, 2015 at 4:42 pm
            BrianP
            Participant

              Tom,

              There actually is a IL-12.  Along the same line as IL-2 but not as toxic.  I don't know much about it but I think they are trying it in combination with vaccines and some other things like Ipi or anti-pd1.

               

               

              http://www.ncbi.nlm.nih.gov/pubmed/19519403

              • October 6, 2015 at 4:42 pm
              BrianP
              Participant

                Tom,

                There actually is a IL-12.  Along the same line as IL-2 but not as toxic.  I don't know much about it but I think they are trying it in combination with vaccines and some other things like Ipi or anti-pd1.

                 

                 

                http://www.ncbi.nlm.nih.gov/pubmed/19519403

                • October 6, 2015 at 4:42 pm
                BrianP
                Participant

                  Tom,

                  There actually is a IL-12.  Along the same line as IL-2 but not as toxic.  I don't know much about it but I think they are trying it in combination with vaccines and some other things like Ipi or anti-pd1.

                   

                   

                  http://www.ncbi.nlm.nih.gov/pubmed/19519403

                • October 6, 2015 at 4:24 pm
                geriakt
                Participant

                  Interluken 2 is not a vaccine. It is an older drug to boost your immune functions. It is very similar to Interferon. 

                  Do your research and read up about it as there will be many side effect when on it and you may feel like you have a bad case of the flu.

                   

                  I wish you the best

                  Tom

                  • October 6, 2015 at 4:24 pm
                  geriakt
                  Participant

                    Interluken 2 is not a vaccine. It is an older drug to boost your immune functions. It is very similar to Interferon. 

                    Do your research and read up about it as there will be many side effect when on it and you may feel like you have a bad case of the flu.

                     

                    I wish you the best

                    Tom

                    • October 7, 2015 at 4:23 am
                    Polymath
                    Participant

                      Hello Anon,

                      I am currently in a trial where IL-12 is injected directly into sub-cutaneous tumors.  I don't think its a vaccine. It is a naturally occurring compound found in the body.  But the intent is to illicit a systemic immune response. It is a form of immunotherapy (similar to the T-Vec trials).  This trial uses the IL-12 injected directly into tumor then immediately followed by electroporation (electric shock) directly at tumor site, and it supposed to make the tumor more absorbent.  It's a rather unpleasant procedure, but no particular lasting pain afterwards.

                      I get my first follow-up scans next week which will determine whether I am responding to the treatment.  I have my doubts, but perhaps its still too soon to say.

                      Aloha,  Gary

                       

                       

                      • October 7, 2015 at 4:23 am
                      Polymath
                      Participant

                        Hello Anon,

                        I am currently in a trial where IL-12 is injected directly into sub-cutaneous tumors.  I don't think its a vaccine. It is a naturally occurring compound found in the body.  But the intent is to illicit a systemic immune response. It is a form of immunotherapy (similar to the T-Vec trials).  This trial uses the IL-12 injected directly into tumor then immediately followed by electroporation (electric shock) directly at tumor site, and it supposed to make the tumor more absorbent.  It's a rather unpleasant procedure, but no particular lasting pain afterwards.

                        I get my first follow-up scans next week which will determine whether I am responding to the treatment.  I have my doubts, but perhaps its still too soon to say.

                        Aloha,  Gary

                         

                         

                        • October 7, 2015 at 4:23 am
                        Polymath
                        Participant

                          Hello Anon,

                          I am currently in a trial where IL-12 is injected directly into sub-cutaneous tumors.  I don't think its a vaccine. It is a naturally occurring compound found in the body.  But the intent is to illicit a systemic immune response. It is a form of immunotherapy (similar to the T-Vec trials).  This trial uses the IL-12 injected directly into tumor then immediately followed by electroporation (electric shock) directly at tumor site, and it supposed to make the tumor more absorbent.  It's a rather unpleasant procedure, but no particular lasting pain afterwards.

                          I get my first follow-up scans next week which will determine whether I am responding to the treatment.  I have my doubts, but perhaps its still too soon to say.

                          Aloha,  Gary

                           

                           

                          • October 7, 2015 at 1:20 pm
                          Bubbles
                          Participant

                            I thought I had an article about IL 12, but can't find it just yet. Brian is right about it. I do have this on intralesional therapy and IL 2….if it helps.

                            http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/05/asco-2015-intralesional-therapy-for.html

                            Wishing you all my best. C

                            • October 7, 2015 at 1:20 pm
                            Bubbles
                            Participant

                              I thought I had an article about IL 12, but can't find it just yet. Brian is right about it. I do have this on intralesional therapy and IL 2….if it helps.

                              http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/05/asco-2015-intralesional-therapy-for.html

                              Wishing you all my best. C

                              • October 7, 2015 at 1:20 pm
                              Bubbles
                              Participant

                                I thought I had an article about IL 12, but can't find it just yet. Brian is right about it. I do have this on intralesional therapy and IL 2….if it helps.

                                http://chaoticallypreciselifeloveandmelanoma.blogspot.com/2015/05/asco-2015-intralesional-therapy-for.html

                                Wishing you all my best. C

                            Viewing 8 reply threads
                            • You must be logged in to reply to this topic.
                            About the MRF Patient Forum

                            The MRF Patient Forum is the oldest and largest online community of people affected by melanoma. It is designed to provide peer support and information to caregivers, patients, family and friends. There is no better place to discuss different parts of your journey with this cancer and find the friends and support resources to make that journey more bearable.

                            The information on the forum is open and accessible to everyone. To add a new topic or to post a reply, you must be a registered user. Please note that you will be able to post both topics and replies anonymously even though you are logged in. All posts must abide by MRF posting policies.

                            Popular Topics