I am curious just how many times nodular melanoma can keep coming back. I was diagnosed originally in February 2012 with stage IIIB. It quickly changed and to date I have had it come back in new locations, but all on the same side of my body, 9 times. I recently had another positive biopsy I am scheduled for a pet scan in 10 days. I have been on multiple chemo drugs which did not work out and the tafinlar and mekinist were to toxic for me. I have been on Keytruda for the last 2 years but they are considering trying something else since I keep getting positive recurrences. I am thankful I’m still doing pretty good but all these surgeries are leaving me with so much scar tissue that is uncomfortable. A small price to pay for keeping me alive I suppose. The doctors keep telling me that they hope this is the last time but I’m beginning to think that 9 years and 9 surgeries may just be my new normal. Has anyone else had this many positive recurrences? The doctors do believe the Keytruda is keeping it from spreading to my organs and slowing it down but it just doesn’t seem to go away. I am just curious if anyone else has gone through this so many times.