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Hoffman-La Roche BRAF inhibitor trial Participants

Forums Cutaneous Melanoma Community Hoffman-La Roche BRAF inhibitor trial Participants

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    MollyB
    Participant

      Hello,

      Hello,

      I am new to MRF and the Bulletin Board. I am a stage IV melanma patient with V600E mutation. For the last two years, I have had random subcutaneous lesions that have been removed by surgery but this June CT scans showed lesions in my lungs and back. Until now I have been very active and healthy. I applied for the La Roche study at Providence Cancer Center in Portland Oregon and was randomized to receive RO5185426. I started the drug August 9th and after 10 days on 960 mg/twice a day I had to stop the drug because of a raised rash over 95% of my body with swelling (especially in my face), joint pain and extreme fatigue. I waiting a deciision about whether to restart the drug and at what dosage

      I am wondering what others on the study are experiencing.  Molly B

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