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Has anyone heard of this trial?
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Has anyone heard of this trial?

› Forums › General Melanoma Community › Has anyone heard of this trial?

  • Post
    • December 30, 2016 at 2:39 pm
    cf91
    Participant

      Was diagnosed with Stage 4 Mel in 2014. Have tried interferon, IL-2, ipi & opdivo. I've had good responses with the opdivo, but have stopped responding now.   My dr wants to try a new clinical trial.  It's a combo of Glembatumumab Vedotin & Varlilumab.  Is anyone familiar with this?  Feel as if I'm running out of options.  Any info/advice is greatly appreciated!

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    • Replies
        • January 1, 2017 at 5:08 am
        debwray
        Participant

          Hi,

          Some positive .but limited responses posted for glembatumumab for heavily pretreated patients as single agent. New trial seems to be led by Patrick Ott of Dana Faber. Useless at posting links on tablet..there was a  poster presentation at Copenhagen conference this autumn.

          Both drugs are by the same company. Assume you are Braf negative ?

          Would also look at Celeste's blog as she is hot on the latest trials and treatments and has put together a list of ones to consider when when treatment possibilities are fewer due to progression on standard treatments. 

          Best wishes

          Deb

          • January 1, 2017 at 5:08 am
          debwray
          Participant

            Hi,

            Some positive .but limited responses posted for glembatumumab for heavily pretreated patients as single agent. New trial seems to be led by Patrick Ott of Dana Faber. Useless at posting links on tablet..there was a  poster presentation at Copenhagen conference this autumn.

            Both drugs are by the same company. Assume you are Braf negative ?

            Would also look at Celeste's blog as she is hot on the latest trials and treatments and has put together a list of ones to consider when when treatment possibilities are fewer due to progression on standard treatments. 

            Best wishes

            Deb

            • January 1, 2017 at 5:08 am
            debwray
            Participant

              Hi,

              Some positive .but limited responses posted for glembatumumab for heavily pretreated patients as single agent. New trial seems to be led by Patrick Ott of Dana Faber. Useless at posting links on tablet..there was a  poster presentation at Copenhagen conference this autumn.

              Both drugs are by the same company. Assume you are Braf negative ?

              Would also look at Celeste's blog as she is hot on the latest trials and treatments and has put together a list of ones to consider when when treatment possibilities are fewer due to progression on standard treatments. 

              Best wishes

              Deb

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