› Forums › General Melanoma Community › GI Inflammation – need advice – getting nervous
- This topic has 1 reply, 1 voice, and was last updated 2 years, 7 months ago by Christinad.
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- August 23, 2021 at 8:48 pm
Hi All –About a week after the 4th combo dose of ipi/nivo I started experiencing daily nausea, stomach upset and reflux/indigestion, which others said they’ve experienced too. It’s to the point now though where I have no appetite and the symptoms are getting worse despite taking anti nausea and antacids. Cycle 1-3 I’d have an occasional bout of nausea and decreased appetite but nothing like this which seemed to come on all of a sudden to the point where I’m miserable and have lost 30 pounds. I saw my oncologist last week who said I’m having greater than expected side effects and said what I’m experiencing is not that common, although having read this forum I’ve read several stories of patients with GI inflammation. He did give me a small dose of Dexamethasone “to perk me up”. Today I also had multiple small bowel movements which is also new. If these side effects are from the immunotherapy Im totally fine and will tough it out but I worry the symptoms are related to disease progression. Maybe Im worrying to much. I’ve had several side effects along the way and have overcome all of them until now. Im hoping this is just a bump in the road. Anyone have a similar situation that wasn’t a bad thing?
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- August 24, 2021 at 5:01 pm
I had a video visit with the NP at my oncologist office who added another antiemetic and reflux medicine to my medication regimen as well as something to help with sleep. She said the immunotherapy is likely causing inflammation of the GI tract which makes me feel much better. I was convinced I had a rapid onset of a progression which she said is probably not the case but can’t be certain without a scan which is scheduled 10/1. She told me signs and symptoms to watch for in the meantime.
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